SLC35B1

 

Full name: solute carrier family 35 member B1 Alias Symbol: UGTREL1
Type: protein-coding gene Cytoband: 17q21.33
Entrez ID: 10237 HGNC ID: HGNC:20798 Ensembl Gene: ENSG00000121073 OMIM ID: 610790
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of SLC35B1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLC35B1 10237 202433_at 0.2505 0.6292
GSE20347 SLC35B1 10237 202433_at 0.0140 0.9381
GSE23400 SLC35B1 10237 202433_at 0.3234 0.0000
GSE26886 SLC35B1 10237 202433_at -0.1103 0.5952
GSE29001 SLC35B1 10237 202433_at 0.1099 0.6814
GSE38129 SLC35B1 10237 202433_at 0.5205 0.0012
GSE45670 SLC35B1 10237 202433_at 0.4396 0.0047
GSE53622 SLC35B1 10237 81537 0.4961 0.0000
GSE53624 SLC35B1 10237 81537 0.4273 0.0000
GSE63941 SLC35B1 10237 202433_at -0.2932 0.4382
GSE77861 SLC35B1 10237 202433_at 0.2245 0.2309
GSE97050 SLC35B1 10237 A_23_P89455 0.8486 0.1642
SRP007169 SLC35B1 10237 RNAseq -0.3257 0.2908
SRP008496 SLC35B1 10237 RNAseq -0.3364 0.0920
SRP064894 SLC35B1 10237 RNAseq 0.3906 0.0360
SRP133303 SLC35B1 10237 RNAseq 0.5016 0.0016
SRP159526 SLC35B1 10237 RNAseq 0.5741 0.0041
SRP193095 SLC35B1 10237 RNAseq -0.1510 0.2879
SRP219564 SLC35B1 10237 RNAseq 0.5195 0.1964
TCGA SLC35B1 10237 RNAseq 0.0766 0.1510

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by SLC35B1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLC35B1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLC35B1 10237 6 2 22
GSE20123 SLC35B1 10237 6 2 22
GSE43470 SLC35B1 10237 3 2 38
GSE46452 SLC35B1 10237 32 0 27
GSE47630 SLC35B1 10237 9 0 31
GSE54993 SLC35B1 10237 2 4 64
GSE54994 SLC35B1 10237 10 5 38
GSE60625 SLC35B1 10237 4 0 7
GSE74703 SLC35B1 10237 3 2 31
GSE74704 SLC35B1 10237 4 1 15
TCGA SLC35B1 10237 27 7 62

Total number of gains: 106; Total number of losses: 25; Total Number of normals: 357.  

 

Somatic mutations of SLC35B1:

 

Generating mutation plots.

 

Highly correlated genes for SLC35B1:

 

Showing top 20/1059 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLC35B1CD530.729872303
SLC35B1KTI120.723947303
SLC35B1MTHFD1L0.710413303
SLC35B1FAM110A0.709034303
SLC35B1SMG80.70812111011
SLC35B1ERLIN10.705262505
SLC35B1SHMT20.693924707
SLC35B1HAS20.693485303
SLC35B1MELK0.691534707
SLC35B1NUP500.684449605
SLC35B1HDGF0.683135606
SLC35B1ESCO20.681254504
SLC35B1EBNA1BP20.681086303
SLC35B1RECQL0.677436404
SLC35B1NOSIP0.674281303
SLC35B1CEP550.672769706
SLC35B1MRPS230.672487705
SLC35B1DHX80.6721071008
SLC35B1TCF190.671692403
SLC35B1EFTUD20.669391604

For details and further investigation, click here