| Full name: torsin 1A interacting protein 1 | Alias Symbol: LAP1B|FLJ13142 | ||
| Type: protein-coding gene | Cytoband: 1q25.2 | ||
| Entrez ID: 26092 | HGNC ID: HGNC:29456 | Ensembl Gene: ENSG00000143337 | OMIM ID: 614512 |
| Drug and gene relationship at DGIdb | |||
Expression of TOR1AIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TOR1AIP1 | 26092 | 212408_at | -0.3451 | 0.4717 | |
| GSE20347 | TOR1AIP1 | 26092 | 212408_at | -0.2211 | 0.1524 | |
| GSE23400 | TOR1AIP1 | 26092 | 212408_at | -0.1980 | 0.0501 | |
| GSE26886 | TOR1AIP1 | 26092 | 212408_at | -0.4301 | 0.0022 | |
| GSE29001 | TOR1AIP1 | 26092 | 212408_at | 0.0824 | 0.7115 | |
| GSE38129 | TOR1AIP1 | 26092 | 212408_at | -0.4145 | 0.0251 | |
| GSE45670 | TOR1AIP1 | 26092 | 212408_at | -0.6604 | 0.0000 | |
| GSE53622 | TOR1AIP1 | 26092 | 81180 | -0.3103 | 0.0000 | |
| GSE53624 | TOR1AIP1 | 26092 | 81180 | -0.0725 | 0.3945 | |
| GSE63941 | TOR1AIP1 | 26092 | 212408_at | -1.1617 | 0.0010 | |
| GSE77861 | TOR1AIP1 | 26092 | 212408_at | 0.2799 | 0.3179 | |
| GSE97050 | TOR1AIP1 | 26092 | A_24_P267997 | -0.3256 | 0.2628 | |
| SRP007169 | TOR1AIP1 | 26092 | RNAseq | -0.3853 | 0.2200 | |
| SRP008496 | TOR1AIP1 | 26092 | RNAseq | 0.0351 | 0.8741 | |
| SRP064894 | TOR1AIP1 | 26092 | RNAseq | -0.4525 | 0.0220 | |
| SRP133303 | TOR1AIP1 | 26092 | RNAseq | -0.2278 | 0.1140 | |
| SRP159526 | TOR1AIP1 | 26092 | RNAseq | -0.3501 | 0.3028 | |
| SRP193095 | TOR1AIP1 | 26092 | RNAseq | -0.1849 | 0.0350 | |
| SRP219564 | TOR1AIP1 | 26092 | RNAseq | -0.5735 | 0.1768 | |
| TCGA | TOR1AIP1 | 26092 | RNAseq | -0.2335 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TOR1AIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TOR1AIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TOR1AIP1 | 26092 | 12 | 0 | 18 | |
| GSE20123 | TOR1AIP1 | 26092 | 12 | 0 | 18 | |
| GSE43470 | TOR1AIP1 | 26092 | 6 | 1 | 36 | |
| GSE46452 | TOR1AIP1 | 26092 | 3 | 1 | 55 | |
| GSE47630 | TOR1AIP1 | 26092 | 14 | 0 | 26 | |
| GSE54993 | TOR1AIP1 | 26092 | 0 | 6 | 64 | |
| GSE54994 | TOR1AIP1 | 26092 | 15 | 0 | 38 | |
| GSE60625 | TOR1AIP1 | 26092 | 0 | 0 | 11 | |
| GSE74703 | TOR1AIP1 | 26092 | 6 | 1 | 29 | |
| GSE74704 | TOR1AIP1 | 26092 | 5 | 0 | 15 | |
| TCGA | TOR1AIP1 | 26092 | 40 | 3 | 53 |
Total number of gains: 113; Total number of losses: 12; Total Number of normals: 363.
Somatic mutations of TOR1AIP1:
Generating mutation plots.
Highly correlated genes for TOR1AIP1:
Showing top 20/789 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TOR1AIP1 | RGMB | 0.765724 | 4 | 0 | 4 |
| TOR1AIP1 | CACNA1C | 0.763487 | 5 | 0 | 5 |
| TOR1AIP1 | MRGPRF | 0.759474 | 5 | 0 | 5 |
| TOR1AIP1 | PPP1R14A | 0.759363 | 4 | 0 | 4 |
| TOR1AIP1 | FNDC5 | 0.759009 | 3 | 0 | 3 |
| TOR1AIP1 | ANGPTL1 | 0.742066 | 5 | 0 | 5 |
| TOR1AIP1 | CADM2 | 0.736628 | 3 | 0 | 3 |
| TOR1AIP1 | DACT3 | 0.736278 | 4 | 0 | 4 |
| TOR1AIP1 | XKR4 | 0.733249 | 4 | 0 | 4 |
| TOR1AIP1 | NEGR1 | 0.731038 | 5 | 0 | 5 |
| TOR1AIP1 | ITPKB | 0.730049 | 5 | 0 | 4 |
| TOR1AIP1 | CASQ2 | 0.728208 | 6 | 0 | 6 |
| TOR1AIP1 | FIBIN | 0.72327 | 4 | 0 | 4 |
| TOR1AIP1 | INMT | 0.722163 | 5 | 0 | 4 |
| TOR1AIP1 | CFL2 | 0.721129 | 5 | 0 | 4 |
| TOR1AIP1 | ITGA1 | 0.719152 | 8 | 0 | 7 |
| TOR1AIP1 | RBPMS2 | 0.717549 | 4 | 0 | 4 |
| TOR1AIP1 | FILIP1 | 0.712462 | 5 | 0 | 5 |
| TOR1AIP1 | ADD1 | 0.712094 | 7 | 0 | 6 |
| TOR1AIP1 | LSM11 | 0.711834 | 4 | 0 | 3 |
For details and further investigation, click here
