| Full name: coiled-coil and C2 domain containing 2A | Alias Symbol: KIAA1345|MKS6|JBTS9 | ||
| Type: protein-coding gene | Cytoband: 4p15.32 | ||
| Entrez ID: 57545 | HGNC ID: HGNC:29253 | Ensembl Gene: ENSG00000048342 | OMIM ID: 612013 |
| Drug and gene relationship at DGIdb | |||
Expression of CC2D2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CC2D2A | 57545 | 234936_s_at | -0.1432 | 0.8197 | |
| GSE26886 | CC2D2A | 57545 | 234936_s_at | 0.4068 | 0.2731 | |
| GSE45670 | CC2D2A | 57545 | 234936_s_at | -0.9635 | 0.0004 | |
| GSE53622 | CC2D2A | 57545 | 11426 | -0.3009 | 0.0341 | |
| GSE53624 | CC2D2A | 57545 | 11426 | -0.0464 | 0.6929 | |
| GSE63941 | CC2D2A | 57545 | 234936_s_at | -1.8207 | 0.0008 | |
| GSE77861 | CC2D2A | 57545 | 234936_s_at | 0.3784 | 0.1261 | |
| GSE97050 | CC2D2A | 57545 | A_23_P413285 | -0.8028 | 0.1455 | |
| SRP007169 | CC2D2A | 57545 | RNAseq | 1.0911 | 0.0401 | |
| SRP008496 | CC2D2A | 57545 | RNAseq | 1.5909 | 0.0005 | |
| SRP064894 | CC2D2A | 57545 | RNAseq | 0.0121 | 0.9606 | |
| SRP133303 | CC2D2A | 57545 | RNAseq | 0.0032 | 0.9836 | |
| SRP159526 | CC2D2A | 57545 | RNAseq | -0.2647 | 0.2274 | |
| SRP193095 | CC2D2A | 57545 | RNAseq | 0.0522 | 0.6391 | |
| SRP219564 | CC2D2A | 57545 | RNAseq | -0.5034 | 0.5409 | |
| TCGA | CC2D2A | 57545 | RNAseq | -0.2860 | 0.0204 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by CC2D2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CC2D2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CC2D2A | 57545 | 0 | 18 | 12 | |
| GSE20123 | CC2D2A | 57545 | 0 | 18 | 12 | |
| GSE43470 | CC2D2A | 57545 | 1 | 15 | 27 | |
| GSE46452 | CC2D2A | 57545 | 1 | 36 | 22 | |
| GSE47630 | CC2D2A | 57545 | 1 | 19 | 20 | |
| GSE54993 | CC2D2A | 57545 | 10 | 0 | 60 | |
| GSE54994 | CC2D2A | 57545 | 4 | 12 | 37 | |
| GSE60625 | CC2D2A | 57545 | 0 | 0 | 11 | |
| GSE74703 | CC2D2A | 57545 | 1 | 13 | 22 | |
| GSE74704 | CC2D2A | 57545 | 0 | 11 | 9 | |
| TCGA | CC2D2A | 57545 | 9 | 48 | 39 |
Total number of gains: 27; Total number of losses: 190; Total Number of normals: 271.
Somatic mutations of CC2D2A:
Generating mutation plots.
Highly correlated genes for CC2D2A:
Showing top 20/723 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CC2D2A | ESRRG | 0.773231 | 3 | 0 | 3 |
| CC2D2A | AFF3 | 0.769794 | 3 | 0 | 3 |
| CC2D2A | C5orf24 | 0.758583 | 3 | 0 | 3 |
| CC2D2A | HOXA4 | 0.755144 | 3 | 0 | 3 |
| CC2D2A | COPZ2 | 0.754303 | 3 | 0 | 3 |
| CC2D2A | JPH2 | 0.749304 | 3 | 0 | 3 |
| CC2D2A | CACNA2D2 | 0.743128 | 3 | 0 | 3 |
| CC2D2A | INMT | 0.739452 | 5 | 0 | 5 |
| CC2D2A | SGCA | 0.734086 | 4 | 0 | 4 |
| CC2D2A | PPP1R14A | 0.72695 | 4 | 0 | 4 |
| CC2D2A | CNTN3 | 0.726621 | 3 | 0 | 3 |
| CC2D2A | PEG3 | 0.726062 | 4 | 0 | 4 |
| CC2D2A | SOBP | 0.71766 | 6 | 0 | 6 |
| CC2D2A | ANGPTL7 | 0.714919 | 4 | 0 | 3 |
| CC2D2A | DAG1 | 0.711353 | 3 | 0 | 3 |
| CC2D2A | PDE3A | 0.710655 | 5 | 0 | 5 |
| CC2D2A | ITGA7 | 0.710347 | 4 | 0 | 4 |
| CC2D2A | PBXIP1 | 0.70831 | 5 | 0 | 5 |
| CC2D2A | IGFBP6 | 0.707214 | 4 | 0 | 4 |
| CC2D2A | CACNA1C | 0.705728 | 5 | 0 | 5 |
For details and further investigation, click here
