| Full name: coagulation factor VII | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 13q34 | ||
| Entrez ID: 2155 | HGNC ID: HGNC:3544 | Ensembl Gene: ENSG00000057593 | OMIM ID: 613878 |
| Drug and gene relationship at DGIdb | |||
F7 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04610 | Complement and coagulation cascades |
Expression of F7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | F7 | 2155 | 207300_s_at | -0.1455 | 0.5394 | |
| GSE20347 | F7 | 2155 | 207300_s_at | -0.0086 | 0.9289 | |
| GSE23400 | F7 | 2155 | 207300_s_at | -0.1811 | 0.0000 | |
| GSE26886 | F7 | 2155 | 237414_at | 0.0620 | 0.5981 | |
| GSE29001 | F7 | 2155 | 207300_s_at | -0.0500 | 0.7793 | |
| GSE38129 | F7 | 2155 | 207300_s_at | -0.1414 | 0.1286 | |
| GSE45670 | F7 | 2155 | 237414_at | 0.0091 | 0.9365 | |
| GSE63941 | F7 | 2155 | 237414_at | 0.1020 | 0.5299 | |
| GSE77861 | F7 | 2155 | 237414_at | -0.1307 | 0.1794 | |
| GSE97050 | F7 | 2155 | A_23_P117298 | -0.0702 | 0.8979 | |
| TCGA | F7 | 2155 | RNAseq | -0.2011 | 0.7046 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by F7 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of F7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | F7 | 2155 | 7 | 12 | 11 | |
| GSE20123 | F7 | 2155 | 7 | 11 | 12 | |
| GSE43470 | F7 | 2155 | 4 | 14 | 25 | |
| GSE46452 | F7 | 2155 | 3 | 31 | 25 | |
| GSE47630 | F7 | 2155 | 3 | 26 | 11 | |
| GSE54993 | F7 | 2155 | 11 | 4 | 55 | |
| GSE54994 | F7 | 2155 | 10 | 9 | 34 | |
| GSE60625 | F7 | 2155 | 0 | 3 | 8 | |
| GSE74703 | F7 | 2155 | 3 | 10 | 23 | |
| GSE74704 | F7 | 2155 | 4 | 9 | 7 | |
| TCGA | F7 | 2155 | 20 | 32 | 44 |
Total number of gains: 72; Total number of losses: 161; Total Number of normals: 255.
Somatic mutations of F7:
Generating mutation plots.
Highly correlated genes for F7:
Showing top 20/786 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| F7 | ATP6V1G2 | 0.739127 | 4 | 0 | 4 |
| F7 | XKR6 | 0.737127 | 3 | 0 | 3 |
| F7 | SYN3 | 0.723581 | 3 | 0 | 3 |
| F7 | NDUFB3 | 0.722589 | 3 | 0 | 3 |
| F7 | CXXC5 | 0.722422 | 3 | 0 | 3 |
| F7 | SELPLG | 0.704331 | 3 | 0 | 3 |
| F7 | TMEM38A | 0.704047 | 3 | 0 | 3 |
| F7 | FGFR1 | 0.702057 | 3 | 0 | 3 |
| F7 | CSN3 | 0.700188 | 3 | 0 | 3 |
| F7 | AMOTL2 | 0.696488 | 3 | 0 | 3 |
| F7 | WDR27 | 0.692597 | 3 | 0 | 3 |
| F7 | IFNA10 | 0.691428 | 5 | 0 | 5 |
| F7 | RORB | 0.691175 | 5 | 0 | 5 |
| F7 | EIF1AY | 0.688007 | 3 | 0 | 3 |
| F7 | CAPZB | 0.687719 | 3 | 0 | 3 |
| F7 | GATA1 | 0.687554 | 6 | 0 | 6 |
| F7 | ATF7 | 0.682676 | 4 | 0 | 4 |
| F7 | ART1 | 0.682559 | 4 | 0 | 4 |
| F7 | S100G | 0.679938 | 4 | 0 | 4 |
| F7 | MAPK8IP3 | 0.675724 | 3 | 0 | 3 |
For details and further investigation, click here
