| Full name: WD repeat domain 27 | Alias Symbol: MGC43690 | ||
| Type: protein-coding gene | Cytoband: 6q27 | ||
| Entrez ID: 253769 | HGNC ID: HGNC:21248 | Ensembl Gene: ENSG00000184465 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDR27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR27 | 253769 | 228326_at | -0.1011 | 0.8715 | |
| GSE26886 | WDR27 | 253769 | 228326_at | 0.3021 | 0.2109 | |
| GSE45670 | WDR27 | 253769 | 228326_at | 0.0519 | 0.8339 | |
| GSE53622 | WDR27 | 253769 | 12759 | 0.2346 | 0.0159 | |
| GSE53624 | WDR27 | 253769 | 12759 | 0.1244 | 0.1733 | |
| GSE63941 | WDR27 | 253769 | 228326_at | -0.0580 | 0.8634 | |
| GSE77861 | WDR27 | 253769 | 235298_at | -0.2367 | 0.0325 | |
| GSE97050 | WDR27 | 253769 | A_32_P415151 | 0.2022 | 0.3632 | |
| SRP007169 | WDR27 | 253769 | RNAseq | 0.2575 | 0.6334 | |
| SRP008496 | WDR27 | 253769 | RNAseq | 0.0711 | 0.8426 | |
| SRP064894 | WDR27 | 253769 | RNAseq | 0.4560 | 0.0411 | |
| SRP133303 | WDR27 | 253769 | RNAseq | 0.1208 | 0.4818 | |
| SRP159526 | WDR27 | 253769 | RNAseq | 0.0986 | 0.7736 | |
| SRP193095 | WDR27 | 253769 | RNAseq | 0.3005 | 0.0272 | |
| SRP219564 | WDR27 | 253769 | RNAseq | 0.1653 | 0.6281 | |
| TCGA | WDR27 | 253769 | RNAseq | 0.0565 | 0.4517 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR27 | 253769 | 4 | 6 | 20 | |
| GSE20123 | WDR27 | 253769 | 4 | 6 | 20 | |
| GSE43470 | WDR27 | 253769 | 3 | 0 | 40 | |
| GSE46452 | WDR27 | 253769 | 3 | 10 | 46 | |
| GSE47630 | WDR27 | 253769 | 7 | 7 | 26 | |
| GSE54993 | WDR27 | 253769 | 4 | 3 | 63 | |
| GSE54994 | WDR27 | 253769 | 10 | 8 | 35 | |
| GSE60625 | WDR27 | 253769 | 1 | 1 | 9 | |
| GSE74703 | WDR27 | 253769 | 3 | 0 | 33 | |
| GSE74704 | WDR27 | 253769 | 2 | 3 | 15 | |
| TCGA | WDR27 | 253769 | 14 | 20 | 62 |
Total number of gains: 55; Total number of losses: 64; Total Number of normals: 369.
Somatic mutations of WDR27:
Generating mutation plots.
Highly correlated genes for WDR27:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR27 | SAMD4B | 0.827343 | 3 | 0 | 3 |
| WDR27 | FBXW7 | 0.804749 | 3 | 0 | 3 |
| WDR27 | ACHE | 0.801623 | 3 | 0 | 3 |
| WDR27 | EXOC3L4 | 0.734824 | 3 | 0 | 3 |
| WDR27 | CDC16 | 0.725681 | 3 | 0 | 3 |
| WDR27 | TRNAU1AP | 0.725617 | 3 | 0 | 3 |
| WDR27 | KRTAP1-3 | 0.72391 | 3 | 0 | 3 |
| WDR27 | MAML2 | 0.711016 | 3 | 0 | 3 |
| WDR27 | EDF1 | 0.700032 | 3 | 0 | 3 |
| WDR27 | CHRNE | 0.699013 | 3 | 0 | 3 |
| WDR27 | F7 | 0.692597 | 3 | 0 | 3 |
| WDR27 | SRSF11 | 0.691372 | 4 | 0 | 3 |
| WDR27 | NFATC4 | 0.681788 | 4 | 0 | 3 |
| WDR27 | OPTN | 0.677696 | 3 | 0 | 3 |
| WDR27 | CCDC84 | 0.675766 | 4 | 0 | 3 |
| WDR27 | LDB1 | 0.672107 | 3 | 0 | 3 |
| WDR27 | DMWD | 0.670009 | 3 | 0 | 3 |
| WDR27 | DCAF8 | 0.668666 | 3 | 0 | 3 |
| WDR27 | LCAT | 0.66248 | 4 | 0 | 3 |
| WDR27 | C6orf163 | 0.662271 | 4 | 0 | 3 |
For details and further investigation, click here
