| Full name: CXXC finger protein 5 | Alias Symbol: HSPC195|RINF|WID | ||
| Type: protein-coding gene | Cytoband: 5q31.2 | ||
| Entrez ID: 51523 | HGNC ID: HGNC:26943 | Ensembl Gene: ENSG00000171604 | OMIM ID: 612752 |
| Drug and gene relationship at DGIdb | |||
Expression of CXXC5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CXXC5 | 51523 | 233955_x_at | -0.6356 | 0.4825 | |
| GSE26886 | CXXC5 | 51523 | 224516_s_at | -1.7948 | 0.0003 | |
| GSE45670 | CXXC5 | 51523 | 233955_x_at | -0.5640 | 0.0929 | |
| GSE53622 | CXXC5 | 51523 | 94836 | -0.7661 | 0.0000 | |
| GSE53624 | CXXC5 | 51523 | 94836 | -1.0239 | 0.0000 | |
| GSE63941 | CXXC5 | 51523 | 233955_x_at | -1.0118 | 0.4053 | |
| GSE77861 | CXXC5 | 51523 | 233955_x_at | -1.0043 | 0.0607 | |
| GSE97050 | CXXC5 | 51523 | A_23_P399001 | 0.0720 | 0.8160 | |
| SRP007169 | CXXC5 | 51523 | RNAseq | -2.6772 | 0.0000 | |
| SRP008496 | CXXC5 | 51523 | RNAseq | -2.5716 | 0.0000 | |
| SRP064894 | CXXC5 | 51523 | RNAseq | -0.6162 | 0.0077 | |
| SRP133303 | CXXC5 | 51523 | RNAseq | -0.5443 | 0.0132 | |
| SRP159526 | CXXC5 | 51523 | RNAseq | -1.9633 | 0.0000 | |
| SRP193095 | CXXC5 | 51523 | RNAseq | -1.0267 | 0.0000 | |
| SRP219564 | CXXC5 | 51523 | RNAseq | -0.6018 | 0.2623 | |
| TCGA | CXXC5 | 51523 | RNAseq | -0.3479 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by CXXC5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CXXC5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CXXC5 | 51523 | 3 | 11 | 16 | |
| GSE20123 | CXXC5 | 51523 | 4 | 11 | 15 | |
| GSE43470 | CXXC5 | 51523 | 4 | 8 | 31 | |
| GSE46452 | CXXC5 | 51523 | 0 | 27 | 32 | |
| GSE47630 | CXXC5 | 51523 | 0 | 20 | 20 | |
| GSE54993 | CXXC5 | 51523 | 9 | 1 | 60 | |
| GSE54994 | CXXC5 | 51523 | 2 | 14 | 37 | |
| GSE60625 | CXXC5 | 51523 | 0 | 0 | 11 | |
| GSE74703 | CXXC5 | 51523 | 3 | 6 | 27 | |
| GSE74704 | CXXC5 | 51523 | 3 | 5 | 12 | |
| TCGA | CXXC5 | 51523 | 4 | 37 | 55 |
Total number of gains: 32; Total number of losses: 140; Total Number of normals: 316.
Somatic mutations of CXXC5:
Generating mutation plots.
Highly correlated genes for CXXC5:
Showing top 20/1036 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CXXC5 | ARHGEF10L | 0.754515 | 7 | 0 | 7 |
| CXXC5 | GFPT1 | 0.751211 | 3 | 0 | 3 |
| CXXC5 | PDZD11 | 0.743694 | 3 | 0 | 3 |
| CXXC5 | COPZ1 | 0.73846 | 3 | 0 | 3 |
| CXXC5 | GTF3C6 | 0.732944 | 3 | 0 | 3 |
| CXXC5 | YPEL3 | 0.732424 | 6 | 0 | 6 |
| CXXC5 | MVP | 0.732149 | 3 | 0 | 3 |
| CXXC5 | F7 | 0.722422 | 3 | 0 | 3 |
| CXXC5 | TBC1D20 | 0.717252 | 5 | 0 | 3 |
| CXXC5 | PINK1 | 0.714287 | 4 | 0 | 3 |
| CXXC5 | C5orf66-AS1 | 0.706855 | 5 | 0 | 5 |
| CXXC5 | TPCN1 | 0.706565 | 8 | 0 | 8 |
| CXXC5 | FBXO42 | 0.704087 | 5 | 0 | 4 |
| CXXC5 | EPG5 | 0.702529 | 3 | 0 | 3 |
| CXXC5 | RAB5A | 0.7022 | 7 | 0 | 7 |
| CXXC5 | SLC16A6 | 0.697152 | 7 | 0 | 7 |
| CXXC5 | TMEM38A | 0.696608 | 3 | 0 | 3 |
| CXXC5 | SNORA68 | 0.69657 | 3 | 0 | 3 |
| CXXC5 | TBC1D23 | 0.695691 | 3 | 0 | 3 |
| CXXC5 | NCOA1 | 0.695661 | 5 | 0 | 4 |
For details and further investigation, click here
