| Full name: RAB1A, member RAS oncogene family | Alias Symbol: YPT1 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 5861 | HGNC ID: HGNC:9758 | Ensembl Gene: ENSG00000138069 | OMIM ID: 179508 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RAB1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB1A | 5861 | 208724_s_at | -0.1371 | 0.7321 | |
| GSE20347 | RAB1A | 5861 | 208724_s_at | -0.0195 | 0.8483 | |
| GSE23400 | RAB1A | 5861 | 208724_s_at | 0.0172 | 0.7763 | |
| GSE26886 | RAB1A | 5861 | 208724_s_at | -0.5479 | 0.0000 | |
| GSE29001 | RAB1A | 5861 | 208724_s_at | -0.0191 | 0.9292 | |
| GSE38129 | RAB1A | 5861 | 208724_s_at | 0.1241 | 0.1485 | |
| GSE45670 | RAB1A | 5861 | 208724_s_at | 0.0950 | 0.2420 | |
| GSE53622 | RAB1A | 5861 | 21169 | -0.1390 | 0.0151 | |
| GSE53624 | RAB1A | 5861 | 21169 | -0.2460 | 0.0000 | |
| GSE63941 | RAB1A | 5861 | 208724_s_at | -0.1440 | 0.5112 | |
| GSE77861 | RAB1A | 5861 | 208724_s_at | -0.0032 | 0.9883 | |
| GSE97050 | RAB1A | 5861 | A_33_P3371055 | 0.2554 | 0.3134 | |
| SRP007169 | RAB1A | 5861 | RNAseq | -0.6981 | 0.0418 | |
| SRP008496 | RAB1A | 5861 | RNAseq | -0.6429 | 0.0004 | |
| SRP064894 | RAB1A | 5861 | RNAseq | -0.2554 | 0.0868 | |
| SRP133303 | RAB1A | 5861 | RNAseq | 0.3550 | 0.0347 | |
| SRP159526 | RAB1A | 5861 | RNAseq | -0.1269 | 0.6164 | |
| SRP193095 | RAB1A | 5861 | RNAseq | -0.3638 | 0.0014 | |
| SRP219564 | RAB1A | 5861 | RNAseq | -0.2062 | 0.4443 | |
| TCGA | RAB1A | 5861 | RNAseq | -0.0304 | 0.4610 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RAB1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB1A | 5861 | 12 | 0 | 18 | |
| GSE20123 | RAB1A | 5861 | 12 | 0 | 18 | |
| GSE43470 | RAB1A | 5861 | 6 | 1 | 36 | |
| GSE46452 | RAB1A | 5861 | 2 | 3 | 54 | |
| GSE47630 | RAB1A | 5861 | 8 | 0 | 32 | |
| GSE54993 | RAB1A | 5861 | 0 | 6 | 64 | |
| GSE54994 | RAB1A | 5861 | 12 | 0 | 41 | |
| GSE60625 | RAB1A | 5861 | 0 | 3 | 8 | |
| GSE74703 | RAB1A | 5861 | 6 | 1 | 29 | |
| GSE74704 | RAB1A | 5861 | 10 | 0 | 10 | |
| TCGA | RAB1A | 5861 | 36 | 2 | 58 |
Total number of gains: 104; Total number of losses: 16; Total Number of normals: 368.
Somatic mutations of RAB1A:
Generating mutation plots.
Highly correlated genes for RAB1A:
Showing top 20/677 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB1A | FAHD1 | 0.800121 | 3 | 0 | 3 |
| RAB1A | SLC35A4 | 0.768641 | 3 | 0 | 3 |
| RAB1A | CCNYL1 | 0.756206 | 3 | 0 | 3 |
| RAB1A | SLC25A43 | 0.755447 | 3 | 0 | 3 |
| RAB1A | SERPINB9 | 0.753236 | 3 | 0 | 3 |
| RAB1A | CAMKMT | 0.747991 | 3 | 0 | 3 |
| RAB1A | PPCS | 0.746308 | 3 | 0 | 3 |
| RAB1A | SURF4 | 0.733287 | 3 | 0 | 3 |
| RAB1A | GNG12 | 0.731495 | 4 | 0 | 4 |
| RAB1A | ELMO2 | 0.729919 | 3 | 0 | 3 |
| RAB1A | MARK3 | 0.723009 | 3 | 0 | 3 |
| RAB1A | DDX52 | 0.722642 | 3 | 0 | 3 |
| RAB1A | TTC23 | 0.718891 | 3 | 0 | 3 |
| RAB1A | YME1L1 | 0.718795 | 4 | 0 | 4 |
| RAB1A | APEH | 0.718332 | 3 | 0 | 3 |
| RAB1A | RHBDF1 | 0.71399 | 4 | 0 | 3 |
| RAB1A | PAIP2 | 0.713868 | 3 | 0 | 3 |
| RAB1A | CHMP4B | 0.712566 | 3 | 0 | 3 |
| RAB1A | ABLIM2 | 0.710996 | 3 | 0 | 3 |
| RAB1A | PPIC | 0.708109 | 4 | 0 | 3 |
For details and further investigation, click here
