| Full name: dynein cytoplasmic 1 light intermediate chain 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 1783 | HGNC ID: HGNC:2966 | Ensembl Gene: ENSG00000135720 | OMIM ID: 611406 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DYNC1LI2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DYNC1LI2 | 1783 | 224616_at | -0.2776 | 0.4977 | |
| GSE20347 | DYNC1LI2 | 1783 | 203590_at | 0.0916 | 0.3910 | |
| GSE23400 | DYNC1LI2 | 1783 | 203590_at | -0.0968 | 0.3468 | |
| GSE26886 | DYNC1LI2 | 1783 | 224616_at | 0.0910 | 0.6511 | |
| GSE29001 | DYNC1LI2 | 1783 | 203590_at | -0.0196 | 0.9311 | |
| GSE38129 | DYNC1LI2 | 1783 | 203590_at | -0.1507 | 0.2711 | |
| GSE45670 | DYNC1LI2 | 1783 | 224616_at | -0.1743 | 0.0200 | |
| GSE53622 | DYNC1LI2 | 1783 | 8218 | -0.0343 | 0.6268 | |
| GSE53624 | DYNC1LI2 | 1783 | 8218 | -0.2422 | 0.0036 | |
| GSE63941 | DYNC1LI2 | 1783 | 224616_at | -0.8253 | 0.0391 | |
| GSE77861 | DYNC1LI2 | 1783 | 224616_at | 0.3493 | 0.0769 | |
| GSE97050 | DYNC1LI2 | 1783 | A_33_P3374758 | -0.0555 | 0.8048 | |
| SRP007169 | DYNC1LI2 | 1783 | RNAseq | 0.2967 | 0.4158 | |
| SRP008496 | DYNC1LI2 | 1783 | RNAseq | 0.2911 | 0.1282 | |
| SRP064894 | DYNC1LI2 | 1783 | RNAseq | -0.1651 | 0.2978 | |
| SRP133303 | DYNC1LI2 | 1783 | RNAseq | 0.2200 | 0.0570 | |
| SRP159526 | DYNC1LI2 | 1783 | RNAseq | -0.0122 | 0.9674 | |
| SRP193095 | DYNC1LI2 | 1783 | RNAseq | -0.0744 | 0.3649 | |
| SRP219564 | DYNC1LI2 | 1783 | RNAseq | -0.4334 | 0.1305 | |
| TCGA | DYNC1LI2 | 1783 | RNAseq | -0.1695 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DYNC1LI2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DYNC1LI2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DYNC1LI2 | 1783 | 8 | 2 | 20 | |
| GSE20123 | DYNC1LI2 | 1783 | 8 | 2 | 20 | |
| GSE43470 | DYNC1LI2 | 1783 | 1 | 8 | 34 | |
| GSE46452 | DYNC1LI2 | 1783 | 38 | 1 | 20 | |
| GSE47630 | DYNC1LI2 | 1783 | 10 | 8 | 22 | |
| GSE54993 | DYNC1LI2 | 1783 | 2 | 4 | 64 | |
| GSE54994 | DYNC1LI2 | 1783 | 8 | 10 | 35 | |
| GSE60625 | DYNC1LI2 | 1783 | 4 | 0 | 7 | |
| GSE74703 | DYNC1LI2 | 1783 | 1 | 5 | 30 | |
| GSE74704 | DYNC1LI2 | 1783 | 5 | 1 | 14 | |
| TCGA | DYNC1LI2 | 1783 | 31 | 11 | 54 |
Total number of gains: 116; Total number of losses: 52; Total Number of normals: 320.
Somatic mutations of DYNC1LI2:
Generating mutation plots.
Highly correlated genes for DYNC1LI2:
Showing top 20/503 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DYNC1LI2 | FAHD1 | 0.806194 | 3 | 0 | 3 |
| DYNC1LI2 | CHM | 0.804003 | 3 | 0 | 3 |
| DYNC1LI2 | BCAS2 | 0.758172 | 3 | 0 | 3 |
| DYNC1LI2 | TRIB1 | 0.751765 | 3 | 0 | 3 |
| DYNC1LI2 | ZNF830 | 0.745221 | 3 | 0 | 3 |
| DYNC1LI2 | EDC4 | 0.734898 | 3 | 0 | 3 |
| DYNC1LI2 | MSL1 | 0.731722 | 3 | 0 | 3 |
| DYNC1LI2 | HSPA4 | 0.722709 | 3 | 0 | 3 |
| DYNC1LI2 | RNF145 | 0.716955 | 4 | 0 | 3 |
| DYNC1LI2 | GIMAP1 | 0.711962 | 3 | 0 | 3 |
| DYNC1LI2 | TUBG2 | 0.702368 | 3 | 0 | 3 |
| DYNC1LI2 | DDIT3 | 0.701344 | 4 | 0 | 3 |
| DYNC1LI2 | FUNDC2 | 0.700484 | 4 | 0 | 3 |
| DYNC1LI2 | COG1 | 0.696631 | 3 | 0 | 3 |
| DYNC1LI2 | JMY | 0.696228 | 5 | 0 | 4 |
| DYNC1LI2 | KLF10 | 0.696175 | 4 | 0 | 3 |
| DYNC1LI2 | CD44 | 0.696122 | 3 | 0 | 3 |
| DYNC1LI2 | TRIP12 | 0.695184 | 3 | 0 | 3 |
| DYNC1LI2 | RGS7BP | 0.694735 | 3 | 0 | 3 |
| DYNC1LI2 | DPM1 | 0.694242 | 3 | 0 | 3 |
For details and further investigation, click here
