| Full name: ubiquitin conjugating enzyme E2 J1 | Alias Symbol: HSPC153|CGI-76|NCUBE1|UBC6 | ||
| Type: protein-coding gene | Cytoband: 6q15 | ||
| Entrez ID: 51465 | HGNC ID: HGNC:17598 | Ensembl Gene: ENSG00000198833 | OMIM ID: 616175 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of UBE2J1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBE2J1 | 51465 | 222435_s_at | -0.8156 | 0.1621 | |
| GSE20347 | UBE2J1 | 51465 | 217823_s_at | -0.7835 | 0.0000 | |
| GSE23400 | UBE2J1 | 51465 | 217825_s_at | -0.1749 | 0.0020 | |
| GSE26886 | UBE2J1 | 51465 | 217823_s_at | -1.8036 | 0.0000 | |
| GSE29001 | UBE2J1 | 51465 | 217823_s_at | -0.5791 | 0.0686 | |
| GSE38129 | UBE2J1 | 51465 | 217823_s_at | -0.5458 | 0.0000 | |
| GSE45670 | UBE2J1 | 51465 | 217823_s_at | -0.2100 | 0.1304 | |
| GSE53622 | UBE2J1 | 51465 | 159168 | -0.5511 | 0.0000 | |
| GSE53624 | UBE2J1 | 51465 | 159168 | -0.6399 | 0.0000 | |
| GSE63941 | UBE2J1 | 51465 | 222435_s_at | -0.1204 | 0.8506 | |
| GSE77861 | UBE2J1 | 51465 | 222435_s_at | -0.6273 | 0.0857 | |
| GSE97050 | UBE2J1 | 51465 | A_33_P3274332 | -0.2151 | 0.5089 | |
| SRP007169 | UBE2J1 | 51465 | RNAseq | -1.1085 | 0.0001 | |
| SRP008496 | UBE2J1 | 51465 | RNAseq | -0.9668 | 0.0000 | |
| SRP064894 | UBE2J1 | 51465 | RNAseq | -0.4580 | 0.0068 | |
| SRP133303 | UBE2J1 | 51465 | RNAseq | -0.1196 | 0.4821 | |
| SRP159526 | UBE2J1 | 51465 | RNAseq | -0.5903 | 0.1312 | |
| SRP193095 | UBE2J1 | 51465 | RNAseq | -0.9426 | 0.0000 | |
| SRP219564 | UBE2J1 | 51465 | RNAseq | -0.4175 | 0.0925 | |
| TCGA | UBE2J1 | 51465 | RNAseq | -0.2228 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UBE2J1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBE2J1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBE2J1 | 51465 | 1 | 4 | 25 | |
| GSE20123 | UBE2J1 | 51465 | 1 | 3 | 26 | |
| GSE43470 | UBE2J1 | 51465 | 3 | 1 | 39 | |
| GSE46452 | UBE2J1 | 51465 | 2 | 11 | 46 | |
| GSE47630 | UBE2J1 | 51465 | 8 | 6 | 26 | |
| GSE54993 | UBE2J1 | 51465 | 3 | 2 | 65 | |
| GSE54994 | UBE2J1 | 51465 | 8 | 8 | 37 | |
| GSE60625 | UBE2J1 | 51465 | 0 | 1 | 10 | |
| GSE74703 | UBE2J1 | 51465 | 3 | 1 | 32 | |
| GSE74704 | UBE2J1 | 51465 | 0 | 2 | 18 | |
| TCGA | UBE2J1 | 51465 | 6 | 21 | 69 |
Total number of gains: 35; Total number of losses: 60; Total Number of normals: 393.
Somatic mutations of UBE2J1:
Generating mutation plots.
Highly correlated genes for UBE2J1:
Showing top 20/1370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBE2J1 | MRPS18C | 0.867966 | 3 | 0 | 3 |
| UBE2J1 | FAM83D | 0.846347 | 3 | 0 | 3 |
| UBE2J1 | TBC1D20 | 0.815892 | 3 | 0 | 3 |
| UBE2J1 | IMPACT | 0.788929 | 3 | 0 | 3 |
| UBE2J1 | SYTL4 | 0.78489 | 3 | 0 | 3 |
| UBE2J1 | PRPF38A | 0.774223 | 3 | 0 | 3 |
| UBE2J1 | RWDD2B | 0.770775 | 3 | 0 | 3 |
| UBE2J1 | MAL2 | 0.760034 | 3 | 0 | 3 |
| UBE2J1 | C2CD2 | 0.743386 | 3 | 0 | 3 |
| UBE2J1 | ARPC1A | 0.74171 | 3 | 0 | 3 |
| UBE2J1 | SH3PXD2A-AS1 | 0.741064 | 3 | 0 | 3 |
| UBE2J1 | TUBB2A | 0.739312 | 3 | 0 | 3 |
| UBE2J1 | DNAJB7 | 0.737054 | 3 | 0 | 3 |
| UBE2J1 | OPHN1 | 0.73657 | 4 | 0 | 4 |
| UBE2J1 | SS18 | 0.732911 | 4 | 0 | 4 |
| UBE2J1 | PSMD8 | 0.732775 | 4 | 0 | 4 |
| UBE2J1 | BRK1 | 0.729922 | 6 | 0 | 5 |
| UBE2J1 | VPS29 | 0.729345 | 5 | 0 | 4 |
| UBE2J1 | GPD2 | 0.728587 | 4 | 0 | 4 |
| UBE2J1 | FAM126B | 0.727539 | 3 | 0 | 3 |
For details and further investigation, click here
