| Full name: neuromedin U | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 10874 | HGNC ID: HGNC:7859 | Ensembl Gene: ENSG00000109255 | OMIM ID: 605103 |
| Drug and gene relationship at DGIdb | |||
Expression of NMU:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NMU | 10874 | 206023_at | -1.3828 | 0.1511 | |
| GSE20347 | NMU | 10874 | 206023_at | -2.4271 | 0.0000 | |
| GSE23400 | NMU | 10874 | 206023_at | -2.2561 | 0.0000 | |
| GSE26886 | NMU | 10874 | 206023_at | -2.4825 | 0.0000 | |
| GSE29001 | NMU | 10874 | 206023_at | -2.1040 | 0.0000 | |
| GSE38129 | NMU | 10874 | 206023_at | -1.2148 | 0.0415 | |
| GSE45670 | NMU | 10874 | 206023_at | -0.9715 | 0.0176 | |
| GSE53622 | NMU | 10874 | 22243 | -2.1581 | 0.0000 | |
| GSE53624 | NMU | 10874 | 22243 | -2.5565 | 0.0000 | |
| GSE63941 | NMU | 10874 | 206023_at | 4.6276 | 0.0051 | |
| GSE77861 | NMU | 10874 | 206023_at | -2.0951 | 0.0004 | |
| GSE97050 | NMU | 10874 | A_23_P69537 | -0.2553 | 0.5859 | |
| SRP007169 | NMU | 10874 | RNAseq | -2.5368 | 0.0006 | |
| SRP008496 | NMU | 10874 | RNAseq | -2.9081 | 0.0000 | |
| SRP064894 | NMU | 10874 | RNAseq | -1.9604 | 0.0000 | |
| SRP133303 | NMU | 10874 | RNAseq | -2.0750 | 0.0000 | |
| SRP159526 | NMU | 10874 | RNAseq | -2.7935 | 0.0000 | |
| SRP193095 | NMU | 10874 | RNAseq | -2.4686 | 0.0000 | |
| SRP219564 | NMU | 10874 | RNAseq | -3.3264 | 0.0021 | |
| TCGA | NMU | 10874 | RNAseq | 0.6441 | 0.0414 |
Upregulated datasets: 1; Downregulated datasets: 15.
Survival by NMU expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NMU:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NMU | 10874 | 3 | 11 | 16 | |
| GSE20123 | NMU | 10874 | 2 | 11 | 17 | |
| GSE43470 | NMU | 10874 | 0 | 14 | 29 | |
| GSE46452 | NMU | 10874 | 1 | 36 | 22 | |
| GSE47630 | NMU | 10874 | 1 | 18 | 21 | |
| GSE54993 | NMU | 10874 | 7 | 0 | 63 | |
| GSE54994 | NMU | 10874 | 2 | 10 | 41 | |
| GSE60625 | NMU | 10874 | 0 | 0 | 11 | |
| GSE74703 | NMU | 10874 | 0 | 12 | 24 | |
| GSE74704 | NMU | 10874 | 1 | 6 | 13 | |
| TCGA | NMU | 10874 | 20 | 26 | 50 |
Total number of gains: 37; Total number of losses: 144; Total Number of normals: 307.
Somatic mutations of NMU:
Generating mutation plots.
Highly correlated genes for NMU:
Showing top 20/1427 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NMU | ACPP | 0.840911 | 11 | 0 | 11 |
| NMU | NIPAL1 | 0.836241 | 3 | 0 | 3 |
| NMU | UPK3B | 0.82665 | 3 | 0 | 3 |
| NMU | EPS8L2 | 0.81927 | 10 | 0 | 10 |
| NMU | SFTA2 | 0.81545 | 4 | 0 | 4 |
| NMU | CLIC3 | 0.814461 | 9 | 0 | 9 |
| NMU | SNORA68 | 0.813426 | 4 | 0 | 4 |
| NMU | CYSRT1 | 0.812521 | 6 | 0 | 6 |
| NMU | EPGN | 0.811445 | 3 | 0 | 3 |
| NMU | NT5C2 | 0.807908 | 11 | 0 | 11 |
| NMU | KRT78 | 0.806963 | 7 | 0 | 7 |
| NMU | GDPD3 | 0.805697 | 11 | 0 | 11 |
| NMU | FAM3B | 0.803431 | 6 | 0 | 6 |
| NMU | TTC9 | 0.803243 | 12 | 0 | 11 |
| NMU | FAM3D | 0.802307 | 8 | 0 | 7 |
| NMU | FUT3 | 0.801972 | 12 | 0 | 11 |
| NMU | ZDHHC13 | 0.796785 | 11 | 0 | 11 |
| NMU | RAB25 | 0.796244 | 12 | 0 | 12 |
| NMU | BLNK | 0.794096 | 11 | 0 | 11 |
| NMU | PITX1 | 0.791099 | 12 | 0 | 11 |
For details and further investigation, click here
