| Full name: family with sequence similarity 181 member B | Alias Symbol: LOC220382|MGC33846 | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 220382 | HGNC ID: HGNC:28512 | Ensembl Gene: ENSG00000182103 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM181B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM181B | 220382 | 231430_at | 0.2368 | 0.8075 | |
| GSE26886 | FAM181B | 220382 | 230994_at | 0.3414 | 0.0429 | |
| GSE45670 | FAM181B | 220382 | 230994_at | -0.0238 | 0.8606 | |
| GSE53622 | FAM181B | 220382 | 98022 | -0.2091 | 0.0276 | |
| GSE53624 | FAM181B | 220382 | 98022 | 0.0106 | 0.9059 | |
| GSE63941 | FAM181B | 220382 | 231430_at | 0.9537 | 0.1857 | |
| GSE77861 | FAM181B | 220382 | 231430_at | 0.1260 | 0.4534 | |
| GSE97050 | FAM181B | 220382 | A_33_P3270623 | -0.1625 | 0.4985 | |
| SRP133303 | FAM181B | 220382 | RNAseq | -0.1117 | 0.4899 | |
| SRP159526 | FAM181B | 220382 | RNAseq | 1.5829 | 0.0102 | |
| SRP193095 | FAM181B | 220382 | RNAseq | 0.3390 | 0.0608 | |
| SRP219564 | FAM181B | 220382 | RNAseq | -0.5388 | 0.2835 | |
| TCGA | FAM181B | 220382 | RNAseq | 0.9027 | 0.0419 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FAM181B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM181B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM181B | 220382 | 2 | 9 | 19 | |
| GSE20123 | FAM181B | 220382 | 2 | 9 | 19 | |
| GSE43470 | FAM181B | 220382 | 2 | 5 | 36 | |
| GSE46452 | FAM181B | 220382 | 5 | 23 | 31 | |
| GSE47630 | FAM181B | 220382 | 3 | 18 | 19 | |
| GSE54993 | FAM181B | 220382 | 8 | 2 | 60 | |
| GSE54994 | FAM181B | 220382 | 6 | 18 | 29 | |
| GSE60625 | FAM181B | 220382 | 0 | 3 | 8 | |
| GSE74703 | FAM181B | 220382 | 1 | 4 | 31 | |
| GSE74704 | FAM181B | 220382 | 2 | 6 | 12 | |
| TCGA | FAM181B | 220382 | 18 | 35 | 43 |
Total number of gains: 49; Total number of losses: 132; Total Number of normals: 307.
Somatic mutations of FAM181B:
Generating mutation plots.
Highly correlated genes for FAM181B:
Showing top 20/154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM181B | TMEM59L | 0.75744 | 3 | 0 | 3 |
| FAM181B | SHISA4 | 0.748949 | 3 | 0 | 3 |
| FAM181B | C1QTNF6 | 0.740615 | 3 | 0 | 3 |
| FAM181B | IGFALS | 0.733316 | 3 | 0 | 3 |
| FAM181B | BPIFB4 | 0.728203 | 3 | 0 | 3 |
| FAM181B | CDR2L | 0.724309 | 3 | 0 | 3 |
| FAM181B | MAPK8IP2 | 0.72387 | 3 | 0 | 3 |
| FAM181B | YY2 | 0.71983 | 3 | 0 | 3 |
| FAM181B | ZIC1 | 0.717903 | 3 | 0 | 3 |
| FAM181B | ST8SIA1 | 0.717234 | 3 | 0 | 3 |
| FAM181B | GNAL | 0.711057 | 4 | 0 | 3 |
| FAM181B | PHOSPHO1 | 0.703686 | 3 | 0 | 3 |
| FAM181B | CEMP1 | 0.700173 | 3 | 0 | 3 |
| FAM181B | FAM171A2 | 0.700153 | 3 | 0 | 3 |
| FAM181B | TP73 | 0.696876 | 3 | 0 | 3 |
| FAM181B | NPEPL1 | 0.696379 | 4 | 0 | 4 |
| FAM181B | KRT25 | 0.688921 | 3 | 0 | 3 |
| FAM181B | ESR1 | 0.682296 | 3 | 0 | 3 |
| FAM181B | KRTAP10-12 | 0.682097 | 3 | 0 | 3 |
| FAM181B | NKX6-3 | 0.679621 | 3 | 0 | 3 |
For details and further investigation, click here
