| Full name: family with sequence similarity 185 member A | Alias Symbol: MGC35361 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 222234 | HGNC ID: HGNC:22412 | Ensembl Gene: ENSG00000222011 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of FAM185A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM185A | 222234 | 1556373_a_at | 0.3691 | 0.5148 | |
| GSE26886 | FAM185A | 222234 | 1556373_a_at | 0.6990 | 0.0557 | |
| GSE45670 | FAM185A | 222234 | 1556373_a_at | 0.0913 | 0.7607 | |
| GSE53622 | FAM185A | 222234 | 76089 | 0.0419 | 0.7406 | |
| GSE53624 | FAM185A | 222234 | 76089 | 0.0369 | 0.6591 | |
| GSE63941 | FAM185A | 222234 | 1556373_a_at | 0.2948 | 0.7223 | |
| GSE77861 | FAM185A | 222234 | 1556373_a_at | 0.5571 | 0.4232 | |
| GSE97050 | FAM185A | 222234 | A_24_P272548 | -0.3526 | 0.2807 | |
| SRP007169 | FAM185A | 222234 | RNAseq | -0.2938 | 0.4944 | |
| SRP008496 | FAM185A | 222234 | RNAseq | 0.4423 | 0.2865 | |
| SRP064894 | FAM185A | 222234 | RNAseq | -0.2088 | 0.0958 | |
| SRP133303 | FAM185A | 222234 | RNAseq | 0.0510 | 0.7406 | |
| SRP159526 | FAM185A | 222234 | RNAseq | -0.2838 | 0.2494 | |
| SRP193095 | FAM185A | 222234 | RNAseq | 0.0354 | 0.7849 | |
| SRP219564 | FAM185A | 222234 | RNAseq | 0.1468 | 0.7206 | |
| TCGA | FAM185A | 222234 | RNAseq | -0.1045 | 0.1680 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM185A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM185A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM185A | 222234 | 13 | 0 | 17 | |
| GSE20123 | FAM185A | 222234 | 12 | 0 | 18 | |
| GSE43470 | FAM185A | 222234 | 6 | 3 | 34 | |
| GSE46452 | FAM185A | 222234 | 10 | 1 | 48 | |
| GSE47630 | FAM185A | 222234 | 7 | 3 | 30 | |
| GSE54993 | FAM185A | 222234 | 1 | 10 | 59 | |
| GSE54994 | FAM185A | 222234 | 15 | 3 | 35 | |
| GSE60625 | FAM185A | 222234 | 0 | 0 | 11 | |
| GSE74703 | FAM185A | 222234 | 6 | 2 | 28 | |
| GSE74704 | FAM185A | 222234 | 9 | 0 | 11 | |
| TCGA | FAM185A | 222234 | 53 | 6 | 37 |
Total number of gains: 132; Total number of losses: 28; Total Number of normals: 328.
Somatic mutations of FAM185A:
Generating mutation plots.
Highly correlated genes for FAM185A:
Showing top 20/266 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM185A | PRKCI | 0.771964 | 3 | 0 | 3 |
| FAM185A | ZNF121 | 0.760911 | 3 | 0 | 3 |
| FAM185A | TAP2 | 0.745962 | 3 | 0 | 3 |
| FAM185A | ZNF623 | 0.744316 | 3 | 0 | 3 |
| FAM185A | HYLS1 | 0.725625 | 3 | 0 | 3 |
| FAM185A | RBM26 | 0.722569 | 3 | 0 | 3 |
| FAM185A | NAA25 | 0.722015 | 3 | 0 | 3 |
| FAM185A | ACBD5 | 0.721201 | 3 | 0 | 3 |
| FAM185A | INTS7 | 0.719901 | 4 | 0 | 3 |
| FAM185A | TTC30B | 0.719407 | 3 | 0 | 3 |
| FAM185A | SMYD2 | 0.70824 | 3 | 0 | 3 |
| FAM185A | PPAT | 0.705545 | 3 | 0 | 3 |
| FAM185A | SRPK1 | 0.703435 | 3 | 0 | 3 |
| FAM185A | TSEN2 | 0.700878 | 3 | 0 | 3 |
| FAM185A | RPL22L1 | 0.69681 | 3 | 0 | 3 |
| FAM185A | CCDC15 | 0.693325 | 3 | 0 | 3 |
| FAM185A | ZNF7 | 0.693308 | 3 | 0 | 3 |
| FAM185A | SURF6 | 0.690626 | 3 | 0 | 3 |
| FAM185A | NAT10 | 0.689297 | 3 | 0 | 3 |
| FAM185A | C12orf73 | 0.685557 | 4 | 0 | 4 |
For details and further investigation, click here
