| Full name: ribosomal protein L22 like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q26.2 | ||
| Entrez ID: 200916 | HGNC ID: HGNC:27610 | Ensembl Gene: ENSG00000163584 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RPL22L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL22L1 | 200916 | 225541_at | 0.1085 | 0.8064 | |
| GSE26886 | RPL22L1 | 200916 | 225541_at | 0.8760 | 0.0002 | |
| GSE45670 | RPL22L1 | 200916 | 225541_at | 0.3992 | 0.1385 | |
| GSE53622 | RPL22L1 | 200916 | 31914 | 0.2572 | 0.0213 | |
| GSE53624 | RPL22L1 | 200916 | 31914 | 0.3908 | 0.0000 | |
| GSE63941 | RPL22L1 | 200916 | 225541_at | 0.3899 | 0.7052 | |
| GSE77861 | RPL22L1 | 200916 | 225541_at | 0.6357 | 0.1527 | |
| GSE97050 | RPL22L1 | 200916 | A_23_P143958 | 0.4092 | 0.3997 | |
| SRP007169 | RPL22L1 | 200916 | RNAseq | 0.1003 | 0.8525 | |
| SRP008496 | RPL22L1 | 200916 | RNAseq | 0.2891 | 0.4496 | |
| SRP064894 | RPL22L1 | 200916 | RNAseq | 0.4018 | 0.1322 | |
| SRP133303 | RPL22L1 | 200916 | RNAseq | 0.3715 | 0.1046 | |
| SRP159526 | RPL22L1 | 200916 | RNAseq | 0.0267 | 0.9585 | |
| SRP193095 | RPL22L1 | 200916 | RNAseq | -0.4527 | 0.0290 | |
| SRP219564 | RPL22L1 | 200916 | RNAseq | 0.4725 | 0.3402 | |
| TCGA | RPL22L1 | 200916 | RNAseq | 0.3903 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPL22L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL22L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL22L1 | 200916 | 24 | 0 | 6 | |
| GSE20123 | RPL22L1 | 200916 | 24 | 0 | 6 | |
| GSE43470 | RPL22L1 | 200916 | 24 | 0 | 19 | |
| GSE46452 | RPL22L1 | 200916 | 19 | 1 | 39 | |
| GSE47630 | RPL22L1 | 200916 | 27 | 2 | 11 | |
| GSE54993 | RPL22L1 | 200916 | 1 | 15 | 54 | |
| GSE54994 | RPL22L1 | 200916 | 41 | 0 | 12 | |
| GSE60625 | RPL22L1 | 200916 | 0 | 6 | 5 | |
| GSE74703 | RPL22L1 | 200916 | 20 | 0 | 16 | |
| GSE74704 | RPL22L1 | 200916 | 16 | 0 | 4 | |
| TCGA | RPL22L1 | 200916 | 80 | 0 | 16 |
Total number of gains: 276; Total number of losses: 24; Total Number of normals: 188.
Somatic mutations of RPL22L1:
Generating mutation plots.
Highly correlated genes for RPL22L1:
Showing top 20/424 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL22L1 | FIP1L1 | 0.761229 | 3 | 0 | 3 |
| RPL22L1 | DUT | 0.757594 | 3 | 0 | 3 |
| RPL22L1 | CNOT2 | 0.750438 | 3 | 0 | 3 |
| RPL22L1 | DCLRE1C | 0.74717 | 3 | 0 | 3 |
| RPL22L1 | BRD4 | 0.740628 | 3 | 0 | 3 |
| RPL22L1 | PLEKHH1 | 0.737893 | 3 | 0 | 3 |
| RPL22L1 | STAT2 | 0.736229 | 3 | 0 | 3 |
| RPL22L1 | MAGOHB | 0.730841 | 3 | 0 | 3 |
| RPL22L1 | PANX1 | 0.726758 | 3 | 0 | 3 |
| RPL22L1 | KRTCAP2 | 0.726623 | 3 | 0 | 3 |
| RPL22L1 | ZAP70 | 0.726232 | 3 | 0 | 3 |
| RPL22L1 | NCAPG | 0.718634 | 3 | 0 | 3 |
| RPL22L1 | SUGP1 | 0.716372 | 3 | 0 | 3 |
| RPL22L1 | POMP | 0.705614 | 3 | 0 | 3 |
| RPL22L1 | ALKBH6 | 0.701016 | 4 | 0 | 4 |
| RPL22L1 | TIFAB | 0.699088 | 3 | 0 | 3 |
| RPL22L1 | MRPL9 | 0.698334 | 4 | 0 | 3 |
| RPL22L1 | GBP1 | 0.698053 | 3 | 0 | 3 |
| RPL22L1 | GGCX | 0.697541 | 4 | 0 | 4 |
| RPL22L1 | AP3D1 | 0.697093 | 3 | 0 | 3 |
For details and further investigation, click here
