| Full name: transporter 2, ATP binding cassette subfamily B member | Alias Symbol: PSF2|RING11|D6S217E | ||
| Type: protein-coding gene | Cytoband: 6p21.32 | ||
| Entrez ID: 6891 | HGNC ID: HGNC:44 | Ensembl Gene: ENSG00000204267 | OMIM ID: 170261 |
| Drug and gene relationship at DGIdb | |||
Expression of TAP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAP2 | 6891 | 225973_at | 0.5936 | 0.4419 | |
| GSE20347 | TAP2 | 6891 | 204769_s_at | 0.1240 | 0.6297 | |
| GSE23400 | TAP2 | 6891 | 204769_s_at | 0.3060 | 0.0082 | |
| GSE26886 | TAP2 | 6891 | 225973_at | 0.0248 | 0.9413 | |
| GSE29001 | TAP2 | 6891 | 204769_s_at | 0.2835 | 0.2167 | |
| GSE38129 | TAP2 | 6891 | 204769_s_at | 0.3659 | 0.0996 | |
| GSE45670 | TAP2 | 6891 | 225973_at | 0.7979 | 0.0143 | |
| GSE53622 | TAP2 | 6891 | 160385 | 0.3461 | 0.0168 | |
| GSE53624 | TAP2 | 6891 | 160385 | 0.2980 | 0.0025 | |
| GSE63941 | TAP2 | 6891 | 225973_at | -0.4364 | 0.6919 | |
| GSE77861 | TAP2 | 6891 | 225973_at | -0.2820 | 0.6898 | |
| GSE97050 | TAP2 | 6891 | A_33_P3214650 | 0.2909 | 0.5546 | |
| SRP007169 | TAP2 | 6891 | RNAseq | -0.1983 | 0.6081 | |
| SRP008496 | TAP2 | 6891 | RNAseq | -0.2180 | 0.3634 | |
| SRP064894 | TAP2 | 6891 | RNAseq | 0.6931 | 0.0010 | |
| SRP133303 | TAP2 | 6891 | RNAseq | 0.5291 | 0.0049 | |
| SRP159526 | TAP2 | 6891 | RNAseq | 0.0639 | 0.8773 | |
| SRP193095 | TAP2 | 6891 | RNAseq | 0.4550 | 0.0010 | |
| SRP219564 | TAP2 | 6891 | RNAseq | 1.2701 | 0.0582 | |
| TCGA | TAP2 | 6891 | RNAseq | 0.3985 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAP2 | 6891 | 7 | 0 | 23 | |
| GSE20123 | TAP2 | 6891 | 7 | 0 | 23 | |
| GSE43470 | TAP2 | 6891 | 6 | 3 | 34 | |
| GSE46452 | TAP2 | 6891 | 2 | 10 | 47 | |
| GSE47630 | TAP2 | 6891 | 8 | 4 | 28 | |
| GSE54993 | TAP2 | 6891 | 3 | 1 | 66 | |
| GSE54994 | TAP2 | 6891 | 11 | 4 | 38 | |
| GSE60625 | TAP2 | 6891 | 1 | 0 | 10 | |
| GSE74703 | TAP2 | 6891 | 5 | 2 | 29 | |
| GSE74704 | TAP2 | 6891 | 3 | 0 | 17 | |
| TCGA | TAP2 | 6891 | 16 | 16 | 64 |
Total number of gains: 69; Total number of losses: 40; Total Number of normals: 379.
Somatic mutations of TAP2:
Generating mutation plots.
Highly correlated genes for TAP2:
Showing top 20/238 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAP2 | EI24 | 0.798402 | 3 | 0 | 3 |
| TAP2 | CXCL5 | 0.75293 | 3 | 0 | 3 |
| TAP2 | NUDT19 | 0.75288 | 3 | 0 | 3 |
| TAP2 | FAM185A | 0.745962 | 3 | 0 | 3 |
| TAP2 | E2F3 | 0.744012 | 3 | 0 | 3 |
| TAP2 | POLG | 0.742964 | 3 | 0 | 3 |
| TAP2 | C12orf73 | 0.726468 | 3 | 0 | 3 |
| TAP2 | LRRC39 | 0.711048 | 3 | 0 | 3 |
| TAP2 | ZBTB9 | 0.708318 | 3 | 0 | 3 |
| TAP2 | HYLS1 | 0.697425 | 3 | 0 | 3 |
| TAP2 | RNASET2 | 0.696766 | 3 | 0 | 3 |
| TAP2 | PIGM | 0.696008 | 3 | 0 | 3 |
| TAP2 | PARP9 | 0.690244 | 7 | 0 | 7 |
| TAP2 | BPNT1 | 0.687553 | 3 | 0 | 3 |
| TAP2 | PPP2R1B | 0.686444 | 4 | 0 | 3 |
| TAP2 | AGTRAP | 0.68585 | 3 | 0 | 3 |
| TAP2 | SPIN4 | 0.685618 | 3 | 0 | 3 |
| TAP2 | EIF3C | 0.671873 | 3 | 0 | 3 |
| TAP2 | CASP8 | 0.671871 | 4 | 0 | 3 |
| TAP2 | TAP1 | 0.666445 | 11 | 0 | 8 |
For details and further investigation, click here
