| Full name: exophilin 5 | Alias Symbol: SLAC2-B | ||
| Type: protein-coding gene | Cytoband: 11q22.3 | ||
| Entrez ID: 23086 | HGNC ID: HGNC:30578 | Ensembl Gene: ENSG00000110723 | OMIM ID: 612878 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of EXPH5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EXPH5 | 23086 | 214734_at | -1.1469 | 0.1835 | |
| GSE20347 | EXPH5 | 23086 | 214734_at | -2.1811 | 0.0000 | |
| GSE23400 | EXPH5 | 23086 | 214734_at | -1.3877 | 0.0000 | |
| GSE26886 | EXPH5 | 23086 | 213929_at | -2.2866 | 0.0000 | |
| GSE29001 | EXPH5 | 23086 | 214734_at | -2.2418 | 0.0001 | |
| GSE38129 | EXPH5 | 23086 | 213929_at | -1.8384 | 0.0002 | |
| GSE45670 | EXPH5 | 23086 | 213929_at | -1.1228 | 0.0061 | |
| GSE53622 | EXPH5 | 23086 | 45040 | -2.0790 | 0.0000 | |
| GSE53624 | EXPH5 | 23086 | 45040 | -2.3199 | 0.0000 | |
| GSE63941 | EXPH5 | 23086 | 214734_at | 2.8863 | 0.0027 | |
| GSE77861 | EXPH5 | 23086 | 214734_at | -0.8584 | 0.0563 | |
| GSE97050 | EXPH5 | 23086 | A_23_P403335 | -1.1040 | 0.2414 | |
| SRP007169 | EXPH5 | 23086 | RNAseq | -3.9722 | 0.0000 | |
| SRP008496 | EXPH5 | 23086 | RNAseq | -3.1418 | 0.0000 | |
| SRP064894 | EXPH5 | 23086 | RNAseq | -3.1824 | 0.0000 | |
| SRP133303 | EXPH5 | 23086 | RNAseq | -2.2905 | 0.0000 | |
| SRP159526 | EXPH5 | 23086 | RNAseq | -2.4063 | 0.0000 | |
| SRP193095 | EXPH5 | 23086 | RNAseq | -2.5999 | 0.0000 | |
| SRP219564 | EXPH5 | 23086 | RNAseq | -2.6417 | 0.0021 | |
| TCGA | EXPH5 | 23086 | RNAseq | -0.0614 | 0.6133 |
Upregulated datasets: 1; Downregulated datasets: 15.
Survival by EXPH5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EXPH5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EXPH5 | 23086 | 0 | 13 | 17 | |
| GSE20123 | EXPH5 | 23086 | 0 | 13 | 17 | |
| GSE43470 | EXPH5 | 23086 | 2 | 6 | 35 | |
| GSE46452 | EXPH5 | 23086 | 3 | 26 | 30 | |
| GSE47630 | EXPH5 | 23086 | 2 | 19 | 19 | |
| GSE54993 | EXPH5 | 23086 | 9 | 1 | 60 | |
| GSE54994 | EXPH5 | 23086 | 5 | 19 | 29 | |
| GSE60625 | EXPH5 | 23086 | 0 | 3 | 8 | |
| GSE74703 | EXPH5 | 23086 | 1 | 4 | 31 | |
| GSE74704 | EXPH5 | 23086 | 0 | 9 | 11 | |
| TCGA | EXPH5 | 23086 | 6 | 48 | 42 |
Total number of gains: 28; Total number of losses: 161; Total Number of normals: 299.
Somatic mutations of EXPH5:
Generating mutation plots.
Highly correlated genes for EXPH5:
Showing top 20/1385 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EXPH5 | UPK3B | 0.868823 | 3 | 0 | 3 |
| EXPH5 | NCCRP1 | 0.851213 | 3 | 0 | 3 |
| EXPH5 | KRT78 | 0.824984 | 7 | 0 | 7 |
| EXPH5 | EVPL | 0.824574 | 12 | 0 | 12 |
| EXPH5 | IQCF1 | 0.820771 | 3 | 0 | 3 |
| EXPH5 | EPGN | 0.817604 | 3 | 0 | 3 |
| EXPH5 | PITX1 | 0.810839 | 11 | 0 | 11 |
| EXPH5 | CLIC3 | 0.81041 | 9 | 0 | 9 |
| EXPH5 | EPS8L1 | 0.809478 | 12 | 0 | 11 |
| EXPH5 | GYS2 | 0.80904 | 10 | 0 | 10 |
| EXPH5 | ENDOU | 0.808879 | 12 | 0 | 12 |
| EXPH5 | NIPAL1 | 0.80869 | 3 | 0 | 3 |
| EXPH5 | EPS8L2 | 0.806895 | 11 | 0 | 10 |
| EXPH5 | HOPX | 0.805687 | 11 | 0 | 11 |
| EXPH5 | SLURP1 | 0.803705 | 11 | 0 | 11 |
| EXPH5 | SCNN1B | 0.803202 | 11 | 0 | 11 |
| EXPH5 | FUT3 | 0.800098 | 11 | 0 | 11 |
| EXPH5 | C1orf116 | 0.798319 | 12 | 0 | 12 |
| EXPH5 | ARHGAP32 | 0.796209 | 11 | 0 | 10 |
| EXPH5 | MAL | 0.795018 | 11 | 0 | 11 |
For details and further investigation, click here
