| Full name: family with sequence similarity 227 member B | Alias Symbol: FLJ32800 | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 196951 | HGNC ID: HGNC:26543 | Ensembl Gene: ENSG00000166262 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM227B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM227B | 196951 | 1557429_s_at | 0.1385 | 0.4899 | |
| GSE26886 | FAM227B | 196951 | 1557429_s_at | 0.2399 | 0.0277 | |
| GSE45670 | FAM227B | 196951 | 1557429_s_at | 0.1926 | 0.2193 | |
| GSE53622 | FAM227B | 196951 | 37759 | -0.5542 | 0.0141 | |
| GSE53624 | FAM227B | 196951 | 37759 | -0.3855 | 0.0002 | |
| GSE63941 | FAM227B | 196951 | 1557429_s_at | 0.5754 | 0.0902 | |
| GSE77861 | FAM227B | 196951 | 1557429_s_at | 0.1167 | 0.4061 | |
| SRP064894 | FAM227B | 196951 | RNAseq | 0.2762 | 0.2436 | |
| SRP133303 | FAM227B | 196951 | RNAseq | 0.0823 | 0.7224 | |
| SRP159526 | FAM227B | 196951 | RNAseq | 0.9078 | 0.1536 | |
| SRP193095 | FAM227B | 196951 | RNAseq | -0.0066 | 0.9651 | |
| SRP219564 | FAM227B | 196951 | RNAseq | -0.6644 | 0.1901 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM227B expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of FAM227B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM227B | 196951 | 5 | 3 | 22 | |
| GSE20123 | FAM227B | 196951 | 5 | 3 | 22 | |
| GSE43470 | FAM227B | 196951 | 5 | 4 | 34 | |
| GSE46452 | FAM227B | 196951 | 3 | 7 | 49 | |
| GSE47630 | FAM227B | 196951 | 8 | 10 | 22 | |
| GSE54993 | FAM227B | 196951 | 4 | 6 | 60 | |
| GSE54994 | FAM227B | 196951 | 5 | 7 | 41 | |
| GSE60625 | FAM227B | 196951 | 4 | 0 | 7 | |
| GSE74703 | FAM227B | 196951 | 5 | 3 | 28 | |
| GSE74704 | FAM227B | 196951 | 2 | 3 | 15 | |
| TCGA | FAM227B | 196951 | 9 | 16 | 71 |
Total number of gains: 55; Total number of losses: 62; Total Number of normals: 371.
Somatic mutations of FAM227B:
Generating mutation plots.
Highly correlated genes for FAM227B:
Showing top 20/40 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM227B | GLS2 | 0.671216 | 3 | 0 | 3 |
| FAM227B | MAPKAPK5-AS1 | 0.659258 | 3 | 0 | 3 |
| FAM227B | IL31RA | 0.657889 | 3 | 0 | 3 |
| FAM227B | SIX4 | 0.642049 | 4 | 0 | 3 |
| FAM227B | C17orf100 | 0.636473 | 3 | 0 | 3 |
| FAM227B | KCNMB3 | 0.633325 | 3 | 0 | 3 |
| FAM227B | RHPN2 | 0.620163 | 4 | 0 | 4 |
| FAM227B | XXYLT1 | 0.612181 | 3 | 0 | 3 |
| FAM227B | HNRNPC | 0.603425 | 3 | 0 | 3 |
| FAM227B | SCCPDH | 0.601691 | 3 | 0 | 3 |
| FAM227B | MSLN | 0.600324 | 3 | 0 | 3 |
| FAM227B | KIAA1324L | 0.599767 | 3 | 0 | 3 |
| FAM227B | HOXD13 | 0.588534 | 4 | 0 | 3 |
| FAM227B | RAB6B | 0.585367 | 3 | 0 | 3 |
| FAM227B | DLX4 | 0.582919 | 3 | 0 | 3 |
| FAM227B | HOXA10 | 0.578712 | 4 | 0 | 3 |
| FAM227B | ACVR2B | 0.578677 | 4 | 0 | 3 |
| FAM227B | AMDHD1 | 0.573692 | 4 | 0 | 3 |
| FAM227B | PKNOX1 | 0.572655 | 3 | 0 | 3 |
| FAM227B | FZD3 | 0.568762 | 4 | 0 | 3 |
For details and further investigation, click here
