| Full name: homeobox A10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7p15.2 | ||
| Entrez ID: 3206 | HGNC ID: HGNC:5100 | Ensembl Gene: ENSG00000253293 | OMIM ID: 142957 |
| Drug and gene relationship at DGIdb | |||
Expression of HOXA10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HOXA10 | 3206 | 213147_at | 1.1579 | 0.0283 | |
| GSE20347 | HOXA10 | 3206 | 213147_at | 0.9455 | 0.0000 | |
| GSE23400 | HOXA10 | 3206 | 213147_at | 0.3552 | 0.0000 | |
| GSE26886 | HOXA10 | 3206 | 213147_at | 1.0443 | 0.0000 | |
| GSE29001 | HOXA10 | 3206 | 213147_at | 1.5538 | 0.0000 | |
| GSE38129 | HOXA10 | 3206 | 213147_at | 1.0695 | 0.0000 | |
| GSE45670 | HOXA10 | 3206 | 213150_at | 2.8903 | 0.0000 | |
| GSE63941 | HOXA10 | 3206 | 213150_at | 3.9804 | 0.0145 | |
| GSE77861 | HOXA10 | 3206 | 213147_at | 0.1386 | 0.2404 | |
| GSE97050 | HOXA10 | 3206 | A_33_P3288649 | 0.1876 | 0.4059 | |
| SRP007169 | HOXA10 | 3206 | RNAseq | 2.2083 | 0.0093 | |
| SRP133303 | HOXA10 | 3206 | RNAseq | 2.5754 | 0.0000 | |
| SRP159526 | HOXA10 | 3206 | RNAseq | 4.2491 | 0.0000 | |
| SRP219564 | HOXA10 | 3206 | RNAseq | 4.2605 | 0.0000 | |
| TCGA | HOXA10 | 3206 | RNAseq | 1.9299 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by HOXA10 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of HOXA10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HOXA10 | 3206 | 16 | 1 | 13 | |
| GSE20123 | HOXA10 | 3206 | 16 | 1 | 13 | |
| GSE43470 | HOXA10 | 3206 | 4 | 0 | 39 | |
| GSE46452 | HOXA10 | 3206 | 10 | 2 | 47 | |
| GSE47630 | HOXA10 | 3206 | 8 | 1 | 31 | |
| GSE54993 | HOXA10 | 3206 | 0 | 6 | 64 | |
| GSE54994 | HOXA10 | 3206 | 21 | 2 | 30 | |
| GSE60625 | HOXA10 | 3206 | 0 | 0 | 11 | |
| GSE74703 | HOXA10 | 3206 | 4 | 0 | 32 | |
| GSE74704 | HOXA10 | 3206 | 10 | 1 | 9 | |
| TCGA | HOXA10 | 3206 | 55 | 6 | 35 |
Total number of gains: 144; Total number of losses: 20; Total Number of normals: 324.
Somatic mutations of HOXA10:
Generating mutation plots.
Highly correlated genes for HOXA10:
Showing top 20/1205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HOXA10 | NTPCR | 0.76351 | 3 | 0 | 3 |
| HOXA10 | ACVR1C | 0.730196 | 5 | 0 | 5 |
| HOXA10 | DEPDC1B | 0.72983 | 3 | 0 | 3 |
| HOXA10 | ZGRF1 | 0.72463 | 3 | 0 | 3 |
| HOXA10 | HOXC10 | 0.707396 | 9 | 0 | 9 |
| HOXA10 | COLEC11 | 0.705475 | 3 | 0 | 3 |
| HOXA10 | MBOAT7 | 0.692421 | 3 | 0 | 3 |
| HOXA10 | PLXNA1 | 0.691105 | 9 | 0 | 8 |
| HOXA10 | POU6F2-AS2 | 0.689396 | 4 | 0 | 4 |
| HOXA10 | MCM4 | 0.688692 | 9 | 0 | 7 |
| HOXA10 | SIX4 | 0.684999 | 5 | 0 | 5 |
| HOXA10 | FAM91A1 | 0.682502 | 4 | 0 | 3 |
| HOXA10 | DNAJB11 | 0.682005 | 4 | 0 | 3 |
| HOXA10 | MTFR2 | 0.679593 | 4 | 0 | 3 |
| HOXA10 | BEND3 | 0.679334 | 4 | 0 | 3 |
| HOXA10 | ZNF598 | 0.67761 | 3 | 0 | 3 |
| HOXA10 | CKAP2L | 0.677063 | 4 | 0 | 4 |
| HOXA10 | CMSS1 | 0.675863 | 4 | 0 | 3 |
| HOXA10 | MTERF3 | 0.675464 | 7 | 0 | 7 |
| HOXA10 | OCIAD2 | 0.675115 | 6 | 0 | 5 |
For details and further investigation, click here
