| Full name: heterogeneous nuclear ribonucleoprotein C | Alias Symbol: hnRNPC | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 3183 | HGNC ID: HGNC:5035 | Ensembl Gene: ENSG00000092199 | OMIM ID: 164020 |
| Drug and gene relationship at DGIdb | |||
Expression of HNRNPC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HNRNPC | 3183 | 214737_x_at | 0.3214 | 0.1072 | |
| GSE20347 | HNRNPC | 3183 | 214737_x_at | 0.4228 | 0.0001 | |
| GSE23400 | HNRNPC | 3183 | 214737_x_at | 0.5212 | 0.0000 | |
| GSE26886 | HNRNPC | 3183 | 214737_x_at | 0.1404 | 0.3306 | |
| GSE29001 | HNRNPC | 3183 | 214737_x_at | 0.2859 | 0.1638 | |
| GSE38129 | HNRNPC | 3183 | 214737_x_at | 0.5100 | 0.0000 | |
| GSE45670 | HNRNPC | 3183 | 214737_x_at | 0.4403 | 0.0004 | |
| GSE53622 | HNRNPC | 3183 | 77468 | 0.1430 | 0.0005 | |
| GSE53624 | HNRNPC | 3183 | 77468 | 0.3714 | 0.0000 | |
| GSE63941 | HNRNPC | 3183 | 214737_x_at | 1.1229 | 0.0000 | |
| GSE77861 | HNRNPC | 3183 | 214737_x_at | 0.3254 | 0.0571 | |
| GSE97050 | HNRNPC | 3183 | A_24_P178423 | 0.1812 | 0.3384 | |
| SRP007169 | HNRNPC | 3183 | RNAseq | -0.0364 | 0.8949 | |
| SRP008496 | HNRNPC | 3183 | RNAseq | -0.1508 | 0.3137 | |
| SRP064894 | HNRNPC | 3183 | RNAseq | 0.1924 | 0.1196 | |
| SRP133303 | HNRNPC | 3183 | RNAseq | 0.4313 | 0.0000 | |
| SRP159526 | HNRNPC | 3183 | RNAseq | 0.3149 | 0.0737 | |
| SRP193095 | HNRNPC | 3183 | RNAseq | 0.0876 | 0.4551 | |
| SRP219564 | HNRNPC | 3183 | RNAseq | 0.2759 | 0.2406 | |
| TCGA | HNRNPC | 3183 | RNAseq | 0.1750 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by HNRNPC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HNRNPC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HNRNPC | 3183 | 9 | 3 | 18 | |
| GSE20123 | HNRNPC | 3183 | 9 | 3 | 18 | |
| GSE43470 | HNRNPC | 3183 | 7 | 2 | 34 | |
| GSE46452 | HNRNPC | 3183 | 19 | 2 | 38 | |
| GSE47630 | HNRNPC | 3183 | 10 | 10 | 20 | |
| GSE54993 | HNRNPC | 3183 | 3 | 11 | 56 | |
| GSE54994 | HNRNPC | 3183 | 18 | 5 | 30 | |
| GSE60625 | HNRNPC | 3183 | 0 | 2 | 9 | |
| GSE74703 | HNRNPC | 3183 | 6 | 2 | 28 | |
| GSE74704 | HNRNPC | 3183 | 4 | 2 | 14 | |
| TCGA | HNRNPC | 3183 | 26 | 17 | 53 |
Total number of gains: 111; Total number of losses: 59; Total Number of normals: 318.
Somatic mutations of HNRNPC:
Generating mutation plots.
Highly correlated genes for HNRNPC:
Showing top 20/1693 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HNRNPC | ELOF1 | 0.818996 | 3 | 0 | 3 |
| HNRNPC | ZNF317 | 0.796643 | 3 | 0 | 3 |
| HNRNPC | IRF2BPL | 0.755732 | 4 | 0 | 3 |
| HNRNPC | UBE2C | 0.753307 | 10 | 0 | 9 |
| HNRNPC | SPATA5 | 0.743095 | 3 | 0 | 3 |
| HNRNPC | BORA | 0.742658 | 8 | 0 | 8 |
| HNRNPC | GIGYF1 | 0.741768 | 3 | 0 | 3 |
| HNRNPC | ATXN1L | 0.733177 | 3 | 0 | 3 |
| HNRNPC | CDCA2 | 0.73026 | 5 | 0 | 5 |
| HNRNPC | ERCC3 | 0.729868 | 9 | 0 | 8 |
| HNRNPC | MAP3K13 | 0.727065 | 4 | 0 | 4 |
| HNRNPC | TPX2 | 0.726578 | 10 | 0 | 10 |
| HNRNPC | LSM4 | 0.722377 | 9 | 0 | 9 |
| HNRNPC | ILF3 | 0.720398 | 9 | 0 | 8 |
| HNRNPC | HNRNPU | 0.719022 | 10 | 0 | 9 |
| HNRNPC | PACSIN3 | 0.718877 | 3 | 0 | 3 |
| HNRNPC | RACGAP1 | 0.718476 | 8 | 0 | 8 |
| HNRNPC | CCT5 | 0.718459 | 9 | 0 | 8 |
| HNRNPC | TRAPPC1 | 0.717554 | 3 | 0 | 3 |
| HNRNPC | NASP | 0.716789 | 12 | 0 | 11 |
For details and further investigation, click here
