| Full name: rhophilin Rho GTPase binding protein 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 85415 | HGNC ID: HGNC:19974 | Ensembl Gene: ENSG00000131941 | OMIM ID: 617932 |
| Drug and gene relationship at DGIdb | |||
Expression of RHPN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHPN2 | 85415 | 227196_at | 0.7023 | 0.2250 | |
| GSE26886 | RHPN2 | 85415 | 227196_at | 2.8651 | 0.0000 | |
| GSE45670 | RHPN2 | 85415 | 227196_at | 0.8299 | 0.0501 | |
| GSE53622 | RHPN2 | 85415 | 1468 | -0.1523 | 0.4246 | |
| GSE53624 | RHPN2 | 85415 | 1468 | -0.5122 | 0.0000 | |
| GSE63941 | RHPN2 | 85415 | 227196_at | 2.7729 | 0.0006 | |
| GSE77861 | RHPN2 | 85415 | 227196_at | 0.6718 | 0.0219 | |
| GSE97050 | RHPN2 | A_21_P0011435 | 0.1988 | 0.5350 | ||
| SRP007169 | RHPN2 | 85415 | RNAseq | 2.6527 | 0.0006 | |
| SRP064894 | RHPN2 | 85415 | RNAseq | 0.5441 | 0.1211 | |
| SRP133303 | RHPN2 | 85415 | RNAseq | 0.9070 | 0.0497 | |
| SRP159526 | RHPN2 | 85415 | RNAseq | 1.4310 | 0.0066 | |
| SRP193095 | RHPN2 | 85415 | RNAseq | 0.1003 | 0.8420 | |
| SRP219564 | RHPN2 | 85415 | RNAseq | 1.1199 | 0.0220 | |
| TCGA | RHPN2 | 85415 | RNAseq | -0.6166 | 0.0001 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by RHPN2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHPN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHPN2 | 85415 | 7 | 6 | 17 | |
| GSE20123 | RHPN2 | 85415 | 7 | 5 | 18 | |
| GSE43470 | RHPN2 | 85415 | 4 | 6 | 33 | |
| GSE46452 | RHPN2 | 85415 | 47 | 1 | 11 | |
| GSE47630 | RHPN2 | 85415 | 8 | 6 | 26 | |
| GSE54993 | RHPN2 | 85415 | 17 | 3 | 50 | |
| GSE54994 | RHPN2 | 85415 | 7 | 9 | 37 | |
| GSE60625 | RHPN2 | 85415 | 9 | 0 | 2 | |
| GSE74703 | RHPN2 | 85415 | 4 | 4 | 28 | |
| GSE74704 | RHPN2 | 85415 | 6 | 3 | 11 | |
| TCGA | RHPN2 | 85415 | 18 | 12 | 66 |
Total number of gains: 134; Total number of losses: 55; Total Number of normals: 299.
Somatic mutations of RHPN2:
Generating mutation plots.
Highly correlated genes for RHPN2:
Showing top 20/497 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHPN2 | SIX4 | 0.768942 | 4 | 0 | 4 |
| RHPN2 | LONP1 | 0.760592 | 5 | 0 | 5 |
| RHPN2 | SART3 | 0.758753 | 3 | 0 | 3 |
| RHPN2 | KRT18 | 0.741116 | 4 | 0 | 3 |
| RHPN2 | CDCA7 | 0.722425 | 4 | 0 | 4 |
| RHPN2 | PUS1 | 0.715035 | 5 | 0 | 5 |
| RHPN2 | RECQL4 | 0.714557 | 5 | 0 | 4 |
| RHPN2 | FRMD6-AS1 | 0.70998 | 3 | 0 | 3 |
| RHPN2 | NUP210 | 0.708708 | 4 | 0 | 4 |
| RHPN2 | POP7 | 0.708208 | 3 | 0 | 3 |
| RHPN2 | LSR | 0.706901 | 5 | 0 | 5 |
| RHPN2 | ITGB3BP | 0.706816 | 4 | 0 | 4 |
| RHPN2 | DUSP12 | 0.703072 | 3 | 0 | 3 |
| RHPN2 | FBRSL1 | 0.70266 | 5 | 0 | 5 |
| RHPN2 | MCM4 | 0.700139 | 5 | 0 | 5 |
| RHPN2 | C4orf48 | 0.696655 | 4 | 0 | 3 |
| RHPN2 | GINS2 | 0.693121 | 4 | 0 | 4 |
| RHPN2 | NUF2 | 0.691688 | 5 | 0 | 4 |
| RHPN2 | MARVELD3 | 0.690891 | 5 | 0 | 5 |
| RHPN2 | MTERF3 | 0.690353 | 4 | 0 | 4 |
For details and further investigation, click here
