| Full name: LIM domain 7 | Alias Symbol: FBX20|KIAA0858 | ||
| Type: protein-coding gene | Cytoband: 13q22.2 | ||
| Entrez ID: 4008 | HGNC ID: HGNC:6646 | Ensembl Gene: ENSG00000136153 | OMIM ID: 604362 |
| Drug and gene relationship at DGIdb | |||
LMO7 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04520 | Adherens junction |
Expression of LMO7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMO7 | 4008 | 242722_at | -1.9477 | 0.0828 | |
| GSE20347 | LMO7 | 4008 | 202674_s_at | -0.5088 | 0.0001 | |
| GSE23400 | LMO7 | 4008 | 202674_s_at | -0.3581 | 0.0000 | |
| GSE26886 | LMO7 | 4008 | 242722_at | -3.8640 | 0.0000 | |
| GSE29001 | LMO7 | 4008 | 202674_s_at | -1.0187 | 0.0074 | |
| GSE38129 | LMO7 | 4008 | 202674_s_at | -0.4875 | 0.0000 | |
| GSE45670 | LMO7 | 4008 | 242722_at | -0.7456 | 0.1072 | |
| GSE53622 | LMO7 | 4008 | 5818 | -2.4514 | 0.0000 | |
| GSE53624 | LMO7 | 4008 | 89885 | -3.0642 | 0.0000 | |
| GSE63941 | LMO7 | 4008 | 242722_at | -2.5878 | 0.0563 | |
| GSE77861 | LMO7 | 4008 | 242722_at | -1.6675 | 0.0038 | |
| GSE97050 | LMO7 | 4008 | A_33_P3280805 | -0.5976 | 0.3997 | |
| SRP007169 | LMO7 | 4008 | RNAseq | -2.8117 | 0.0000 | |
| SRP008496 | LMO7 | 4008 | RNAseq | -3.1544 | 0.0000 | |
| SRP064894 | LMO7 | 4008 | RNAseq | -4.0976 | 0.0000 | |
| SRP133303 | LMO7 | 4008 | RNAseq | -2.0598 | 0.0000 | |
| SRP159526 | LMO7 | 4008 | RNAseq | -3.3307 | 0.0000 | |
| SRP193095 | LMO7 | 4008 | RNAseq | -3.3781 | 0.0000 | |
| SRP219564 | LMO7 | 4008 | RNAseq | -3.3746 | 0.0001 | |
| TCGA | LMO7 | 4008 | RNAseq | -0.2828 | 0.0053 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by LMO7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMO7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMO7 | 4008 | 3 | 11 | 16 | |
| GSE20123 | LMO7 | 4008 | 3 | 10 | 17 | |
| GSE43470 | LMO7 | 4008 | 4 | 10 | 29 | |
| GSE46452 | LMO7 | 4008 | 1 | 32 | 26 | |
| GSE47630 | LMO7 | 4008 | 3 | 27 | 10 | |
| GSE54993 | LMO7 | 4008 | 11 | 3 | 56 | |
| GSE54994 | LMO7 | 4008 | 3 | 14 | 36 | |
| GSE60625 | LMO7 | 4008 | 0 | 3 | 8 | |
| GSE74703 | LMO7 | 4008 | 3 | 8 | 25 | |
| GSE74704 | LMO7 | 4008 | 1 | 9 | 10 | |
| TCGA | LMO7 | 4008 | 12 | 33 | 51 |
Total number of gains: 44; Total number of losses: 160; Total Number of normals: 284.
Somatic mutations of LMO7:
Generating mutation plots.
Highly correlated genes for LMO7:
Showing top 20/1346 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMO7 | NCCRP1 | 0.903534 | 3 | 0 | 3 |
| LMO7 | FAM3D | 0.878337 | 7 | 0 | 7 |
| LMO7 | UPK3B | 0.872533 | 3 | 0 | 3 |
| LMO7 | PRSS27 | 0.869625 | 7 | 0 | 7 |
| LMO7 | EPS8L1 | 0.84887 | 11 | 0 | 11 |
| LMO7 | TMPRSS11B | 0.847729 | 7 | 0 | 7 |
| LMO7 | SMIM5 | 0.847599 | 6 | 0 | 6 |
| LMO7 | TMPRSS11A | 0.843702 | 3 | 0 | 3 |
| LMO7 | CYSRT1 | 0.842064 | 6 | 0 | 6 |
| LMO7 | SPINK7 | 0.840909 | 7 | 0 | 7 |
| LMO7 | C6orf132 | 0.838655 | 7 | 0 | 7 |
| LMO7 | LIPH | 0.830022 | 7 | 0 | 7 |
| LMO7 | FAM214A | 0.829211 | 7 | 0 | 7 |
| LMO7 | VSIG2 | 0.827922 | 7 | 0 | 7 |
| LMO7 | FAM3B | 0.827448 | 6 | 0 | 6 |
| LMO7 | RAET1E | 0.824879 | 7 | 0 | 7 |
| LMO7 | KLB | 0.824429 | 6 | 0 | 6 |
| LMO7 | PLEKHA7 | 0.821579 | 6 | 0 | 6 |
| LMO7 | OTOP3 | 0.820807 | 3 | 0 | 3 |
| LMO7 | BNIPL | 0.82019 | 7 | 0 | 7 |
For details and further investigation, click here
