| Full name: POM121 transmembrane nucleoporin | Alias Symbol: KIAA0618|DKFZP586G1822|DKFZP586P2220|POM121A | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 9883 | HGNC ID: HGNC:19702 | Ensembl Gene: ENSG00000196313 | OMIM ID: 615753 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of POM121:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | POM121 | 9883 | 205096_at | 0.6535 | 0.1039 | |
| GSE20347 | POM121 | 9883 | 205096_at | 0.0603 | 0.5998 | |
| GSE23400 | POM121 | 9883 | 205096_at | 0.0900 | 0.0868 | |
| GSE26886 | POM121 | 9883 | 205096_at | 0.0446 | 0.8012 | |
| GSE29001 | POM121 | 9883 | 205096_at | 0.1626 | 0.3740 | |
| GSE38129 | POM121 | 9883 | 205096_at | 0.1317 | 0.2323 | |
| GSE45670 | POM121 | 9883 | 205096_at | 0.2134 | 0.1066 | |
| GSE53622 | POM121 | 9883 | 17011 | 0.2579 | 0.0071 | |
| GSE53624 | POM121 | 9883 | 22726 | 0.3255 | 0.0001 | |
| GSE63941 | POM121 | 9883 | 205096_at | 0.8142 | 0.0326 | |
| GSE77861 | POM121 | 9883 | 205096_at | 0.0609 | 0.5693 | |
| GSE97050 | POM121 | 9883 | A_23_P215435 | 0.0032 | 0.9933 | |
| SRP007169 | POM121 | 9883 | RNAseq | 1.0144 | 0.0028 | |
| SRP008496 | POM121 | 9883 | RNAseq | 0.8991 | 0.0001 | |
| SRP064894 | POM121 | 9883 | RNAseq | 0.1790 | 0.2928 | |
| SRP133303 | POM121 | 9883 | RNAseq | 0.2309 | 0.0768 | |
| SRP159526 | POM121 | 9883 | RNAseq | 0.4925 | 0.0117 | |
| SRP193095 | POM121 | 9883 | RNAseq | 0.4476 | 0.0008 | |
| SRP219564 | POM121 | 9883 | RNAseq | 0.3307 | 0.2089 | |
| TCGA | POM121 | 9883 | RNAseq | -0.0100 | 0.8084 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by POM121 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of POM121:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | POM121 | 9883 | 12 | 1 | 17 | |
| GSE20123 | POM121 | 9883 | 11 | 1 | 18 | |
| GSE43470 | POM121 | 9883 | 3 | 2 | 38 | |
| GSE46452 | POM121 | 9883 | 12 | 0 | 47 | |
| GSE47630 | POM121 | 9883 | 7 | 2 | 31 | |
| GSE54993 | POM121 | 9883 | 2 | 7 | 61 | |
| GSE54994 | POM121 | 9883 | 13 | 2 | 38 | |
| GSE60625 | POM121 | 9883 | 0 | 0 | 11 | |
| GSE74703 | POM121 | 9883 | 3 | 1 | 32 | |
| GSE74704 | POM121 | 9883 | 7 | 1 | 12 | |
| TCGA | POM121 | 9883 | 45 | 8 | 43 |
Total number of gains: 115; Total number of losses: 25; Total Number of normals: 348.
Somatic mutations of POM121:
Generating mutation plots.
Highly correlated genes for POM121:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| POM121 | SPDYE1 | 0.768002 | 3 | 0 | 3 |
| POM121 | DSCC1 | 0.759374 | 3 | 0 | 3 |
| POM121 | SMC3 | 0.745375 | 3 | 0 | 3 |
| POM121 | LSM14B | 0.741393 | 3 | 0 | 3 |
| POM121 | SMAD1 | 0.736299 | 3 | 0 | 3 |
| POM121 | MTBP | 0.733821 | 3 | 0 | 3 |
| POM121 | PSMB7 | 0.730956 | 3 | 0 | 3 |
| POM121 | KIAA1522 | 0.729553 | 3 | 0 | 3 |
| POM121 | PALB2 | 0.726073 | 3 | 0 | 3 |
| POM121 | CCNA2 | 0.725105 | 3 | 0 | 3 |
| POM121 | SPDYE5 | 0.724012 | 3 | 0 | 3 |
| POM121 | ANAPC10 | 0.717466 | 3 | 0 | 3 |
| POM121 | FASTKD3 | 0.716687 | 3 | 0 | 3 |
| POM121 | RAD18 | 0.712427 | 3 | 0 | 3 |
| POM121 | XPO5 | 0.710953 | 3 | 0 | 3 |
| POM121 | KDM1A | 0.705762 | 3 | 0 | 3 |
| POM121 | SPDYE3 | 0.704768 | 3 | 0 | 3 |
| POM121 | RSBN1L | 0.703804 | 3 | 0 | 3 |
| POM121 | PPIL4 | 0.703099 | 3 | 0 | 3 |
| POM121 | LEMD2 | 0.702623 | 3 | 0 | 3 |
For details and further investigation, click here
