| Full name: ubiquitin specific peptidase 38 | Alias Symbol: KIAA1891|HP43.8KD | ||
| Type: protein-coding gene | Cytoband: 4q31.21 | ||
| Entrez ID: 84640 | HGNC ID: HGNC:20067 | Ensembl Gene: ENSG00000170185 | OMIM ID: 618322 |
| Drug and gene relationship at DGIdb | |||
Expression of USP38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | USP38 | 84640 | 223288_at | 0.1446 | 0.7041 | |
| GSE26886 | USP38 | 84640 | 223288_at | -0.9310 | 0.0066 | |
| GSE45670 | USP38 | 84640 | 223288_at | 0.0090 | 0.9585 | |
| GSE53622 | USP38 | 84640 | 36680 | -0.2612 | 0.0000 | |
| GSE53624 | USP38 | 84640 | 36680 | -0.3890 | 0.0000 | |
| GSE63941 | USP38 | 84640 | 223288_at | -0.5996 | 0.0680 | |
| GSE77861 | USP38 | 84640 | 223288_at | -0.6282 | 0.0893 | |
| GSE97050 | USP38 | 84640 | A_33_P3378509 | 0.2673 | 0.3167 | |
| SRP007169 | USP38 | 84640 | RNAseq | -0.9370 | 0.0376 | |
| SRP008496 | USP38 | 84640 | RNAseq | -0.8291 | 0.0007 | |
| SRP064894 | USP38 | 84640 | RNAseq | -0.8251 | 0.0000 | |
| SRP133303 | USP38 | 84640 | RNAseq | 0.1905 | 0.1847 | |
| SRP159526 | USP38 | 84640 | RNAseq | -0.1303 | 0.5370 | |
| SRP193095 | USP38 | 84640 | RNAseq | -0.4440 | 0.0007 | |
| SRP219564 | USP38 | 84640 | RNAseq | -0.5548 | 0.0692 | |
| TCGA | USP38 | 84640 | RNAseq | -0.1019 | 0.0316 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by USP38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of USP38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | USP38 | 84640 | 0 | 12 | 18 | |
| GSE20123 | USP38 | 84640 | 0 | 12 | 18 | |
| GSE43470 | USP38 | 84640 | 0 | 13 | 30 | |
| GSE46452 | USP38 | 84640 | 1 | 36 | 22 | |
| GSE47630 | USP38 | 84640 | 0 | 22 | 18 | |
| GSE54993 | USP38 | 84640 | 10 | 0 | 60 | |
| GSE54994 | USP38 | 84640 | 2 | 11 | 40 | |
| GSE60625 | USP38 | 84640 | 0 | 1 | 10 | |
| GSE74703 | USP38 | 84640 | 0 | 11 | 25 | |
| GSE74704 | USP38 | 84640 | 0 | 6 | 14 | |
| TCGA | USP38 | 84640 | 14 | 30 | 52 |
Total number of gains: 27; Total number of losses: 154; Total Number of normals: 307.
Somatic mutations of USP38:
Generating mutation plots.
Highly correlated genes for USP38:
Showing top 20/754 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| USP38 | VCPIP1 | 0.854914 | 3 | 0 | 3 |
| USP38 | SNX30 | 0.815436 | 3 | 0 | 3 |
| USP38 | ARPC1A | 0.815422 | 3 | 0 | 3 |
| USP38 | MRFAP1L1 | 0.802308 | 3 | 0 | 3 |
| USP38 | CDYL | 0.796146 | 3 | 0 | 3 |
| USP38 | RMND1 | 0.794719 | 3 | 0 | 3 |
| USP38 | PPP1R2 | 0.792668 | 3 | 0 | 3 |
| USP38 | PEX2 | 0.791063 | 3 | 0 | 3 |
| USP38 | UGP2 | 0.787985 | 3 | 0 | 3 |
| USP38 | PSEN1 | 0.783939 | 3 | 0 | 3 |
| USP38 | SMURF1 | 0.776697 | 3 | 0 | 3 |
| USP38 | TANC1 | 0.768558 | 3 | 0 | 3 |
| USP38 | PRMT6 | 0.766845 | 3 | 0 | 3 |
| USP38 | PALB2 | 0.766385 | 3 | 0 | 3 |
| USP38 | IMPACT | 0.765337 | 3 | 0 | 3 |
| USP38 | TET2 | 0.764327 | 5 | 0 | 4 |
| USP38 | TM2D2 | 0.75816 | 3 | 0 | 3 |
| USP38 | SEC61B | 0.752738 | 3 | 0 | 3 |
| USP38 | PPM1L | 0.752473 | 3 | 0 | 3 |
| USP38 | GOLGA4 | 0.750145 | 4 | 0 | 4 |
For details and further investigation, click here
