| Full name: partner of NOB1 homolog | Alias Symbol: RRP20 | ||
| Type: protein-coding gene | Cytoband: 2p14 | ||
| Entrez ID: 56902 | HGNC ID: HGNC:32790 | Ensembl Gene: ENSG00000115946 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PNO1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PNO1 | 56902 | 203622_s_at | 0.9043 | 0.0657 | |
| GSE20347 | PNO1 | 56902 | 211697_x_at | 0.2594 | 0.1052 | |
| GSE23400 | PNO1 | 56902 | 211697_x_at | 0.2006 | 0.0004 | |
| GSE26886 | PNO1 | 56902 | 211697_x_at | -0.1709 | 0.4081 | |
| GSE29001 | PNO1 | 56902 | 203622_s_at | 0.8751 | 0.0236 | |
| GSE38129 | PNO1 | 56902 | 211697_x_at | 0.1943 | 0.1191 | |
| GSE45670 | PNO1 | 56902 | 203622_s_at | 0.7736 | 0.0057 | |
| GSE53622 | PNO1 | 56902 | 65148 | 0.8355 | 0.0000 | |
| GSE53624 | PNO1 | 56902 | 65148 | 0.7329 | 0.0000 | |
| GSE63941 | PNO1 | 56902 | 203622_s_at | 1.1974 | 0.0111 | |
| GSE77861 | PNO1 | 56902 | 211697_x_at | 0.0527 | 0.7438 | |
| GSE97050 | PNO1 | 56902 | A_24_P336853 | 0.7531 | 0.1949 | |
| SRP007169 | PNO1 | 56902 | RNAseq | 1.0595 | 0.0051 | |
| SRP008496 | PNO1 | 56902 | RNAseq | 1.4448 | 0.0000 | |
| SRP064894 | PNO1 | 56902 | RNAseq | 0.4189 | 0.0187 | |
| SRP133303 | PNO1 | 56902 | RNAseq | 0.8271 | 0.0000 | |
| SRP159526 | PNO1 | 56902 | RNAseq | 1.1523 | 0.0019 | |
| SRP193095 | PNO1 | 56902 | RNAseq | 0.6234 | 0.0000 | |
| SRP219564 | PNO1 | 56902 | RNAseq | 0.3995 | 0.2111 | |
| TCGA | PNO1 | 56902 | RNAseq | 0.2148 | 0.0001 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by PNO1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PNO1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PNO1 | 56902 | 11 | 0 | 19 | |
| GSE20123 | PNO1 | 56902 | 11 | 0 | 19 | |
| GSE43470 | PNO1 | 56902 | 6 | 0 | 37 | |
| GSE46452 | PNO1 | 56902 | 2 | 3 | 54 | |
| GSE47630 | PNO1 | 56902 | 7 | 0 | 33 | |
| GSE54993 | PNO1 | 56902 | 0 | 6 | 64 | |
| GSE54994 | PNO1 | 56902 | 12 | 0 | 41 | |
| GSE60625 | PNO1 | 56902 | 0 | 3 | 8 | |
| GSE74703 | PNO1 | 56902 | 6 | 0 | 30 | |
| GSE74704 | PNO1 | 56902 | 9 | 0 | 11 | |
| TCGA | PNO1 | 56902 | 36 | 2 | 58 |
Total number of gains: 100; Total number of losses: 14; Total Number of normals: 374.
Somatic mutations of PNO1:
Generating mutation plots.
Highly correlated genes for PNO1:
Showing top 20/1198 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PNO1 | CDCA2 | 0.838574 | 3 | 0 | 3 |
| PNO1 | NUDT5 | 0.753754 | 4 | 0 | 4 |
| PNO1 | POLR2D | 0.751102 | 7 | 0 | 7 |
| PNO1 | IMP4 | 0.743545 | 7 | 0 | 7 |
| PNO1 | WDR92 | 0.739032 | 3 | 0 | 3 |
| PNO1 | TRNT1 | 0.737946 | 3 | 0 | 3 |
| PNO1 | EME1 | 0.737505 | 4 | 0 | 4 |
| PNO1 | GEMIN6 | 0.732332 | 7 | 0 | 7 |
| PNO1 | TNFAIP1 | 0.731825 | 3 | 0 | 3 |
| PNO1 | CTU2 | 0.728893 | 5 | 0 | 5 |
| PNO1 | FBXO28 | 0.723863 | 3 | 0 | 3 |
| PNO1 | CD163 | 0.723318 | 3 | 0 | 3 |
| PNO1 | KTI12 | 0.720626 | 3 | 0 | 3 |
| PNO1 | NIPA2 | 0.720447 | 4 | 0 | 4 |
| PNO1 | DHX33 | 0.71774 | 6 | 0 | 6 |
| PNO1 | USE1 | 0.714442 | 3 | 0 | 3 |
| PNO1 | ISCA1 | 0.713276 | 3 | 0 | 3 |
| PNO1 | WDR54 | 0.713059 | 5 | 0 | 5 |
| PNO1 | ANLN | 0.711523 | 5 | 0 | 5 |
| PNO1 | ARL6IP6 | 0.710493 | 5 | 0 | 4 |
For details and further investigation, click here
