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Multi-Omics Database of ESCC

 

NUP205

 

Full name: nucleoporin 205 Alias Symbol: KIAA0225
Type: protein-coding gene Cytoband: 7q33
Entrez ID: 23165 HGNC ID: HGNC:18658 Ensembl Gene: ENSG00000155561 OMIM ID: 614352
Drug and gene relationship at DGIdb

 

Expression of NUP205:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NUP205 23165 212247_at 0.3229 0.6268
GSE20347 NUP205 23165 212247_at 0.6396 0.0005
GSE23400 NUP205 23165 212247_at 0.7823 0.0000
GSE26886 NUP205 23165 212247_at -0.1838 0.5278
GSE29001 NUP205 23165 212247_at 0.6835 0.0032
GSE38129 NUP205 23165 212247_at 0.8132 0.0000
GSE45670 NUP205 23165 212247_at 0.5156 0.0089
GSE53622 NUP205 23165 61371 0.6479 0.0000
GSE53624 NUP205 23165 61371 0.7229 0.0000
GSE63941 NUP205 23165 212247_at 0.9141 0.0533
GSE77861 NUP205 23165 212247_at 0.7023 0.0096
GSE97050 NUP205 23165 A_32_P51084 0.3174 0.2877
SRP007169 NUP205 23165 RNAseq 1.5699 0.0000
SRP008496 NUP205 23165 RNAseq 1.1718 0.0000
SRP064894 NUP205 23165 RNAseq 0.4564 0.0488
SRP133303 NUP205 23165 RNAseq 0.6881 0.0004
SRP159526 NUP205 23165 RNAseq 0.4603 0.1027
SRP193095 NUP205 23165 RNAseq 0.4168 0.0006
SRP219564 NUP205 23165 RNAseq -0.1183 0.6963
TCGA NUP205 23165 RNAseq 0.2095 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by NUP205 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NUP205:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NUP205 23165 5 2 23
GSE20123 NUP205 23165 5 2 23
GSE43470 NUP205 23165 2 3 38
GSE46452 NUP205 23165 7 2 50
GSE47630 NUP205 23165 7 4 29
GSE54993 NUP205 23165 3 5 62
GSE54994 NUP205 23165 6 8 39
GSE60625 NUP205 23165 0 0 11
GSE74703 NUP205 23165 2 3 31
GSE74704 NUP205 23165 2 2 16
TCGA NUP205 23165 28 23 45

Total number of gains: 67; Total number of losses: 54; Total Number of normals: 367.  


 

Somatic mutations of NUP205:

 

Generating mutation plots.

 

Highly correlated genes for NUP205:

 

Showing top 20/1474 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NUP205MKLN10.821051303
NUP205DNMBP0.789578303
NUP205NEDD10.771903303
NUP205YLPM10.770725505
NUP205DUS3L0.760641303
NUP205ATM0.740076303
NUP205C1QA0.729204303
NUP205HRH10.726849303
NUP205CEP550.72373610010
NUP205ZMYM60.723542303
NUP205SCRN10.722806404
NUP205TRAF70.719569404
NUP205NUP350.714169403
NUP205INHBB0.711636303
NUP205C1QB0.710485303
NUP205NIPA20.706736808
NUP205CEP410.706355403
NUP205PRPF38A0.705386303
NUP205PTK20.703132706
NUP205ANAPC10.701728303

For details and further investigation, click here