| Full name: nuclear receptor binding factor 2 | Alias Symbol: DKFZp564C1664|FLJ30395|COPR1|COPR2 | ||
| Type: protein-coding gene | Cytoband: 10q21.3 | ||
| Entrez ID: 29982 | HGNC ID: HGNC:19692 | Ensembl Gene: ENSG00000148572 | OMIM ID: 616477 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NRBF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRBF2 | 29982 | 221803_s_at | 0.1936 | 0.7610 | |
| GSE20347 | NRBF2 | 29982 | 221803_s_at | 0.0388 | 0.8900 | |
| GSE23400 | NRBF2 | 29982 | 221803_s_at | 0.1681 | 0.0221 | |
| GSE26886 | NRBF2 | 29982 | 221803_s_at | -0.2741 | 0.2499 | |
| GSE29001 | NRBF2 | 29982 | 221803_s_at | 0.0939 | 0.8381 | |
| GSE38129 | NRBF2 | 29982 | 221803_s_at | 0.3320 | 0.0838 | |
| GSE45670 | NRBF2 | 29982 | 221803_s_at | 0.6798 | 0.0230 | |
| GSE53622 | NRBF2 | 29982 | 56735 | 0.3655 | 0.0000 | |
| GSE53624 | NRBF2 | 29982 | 56735 | 0.4176 | 0.0000 | |
| GSE63941 | NRBF2 | 29982 | 223650_s_at | -0.4063 | 0.5190 | |
| GSE77861 | NRBF2 | 29982 | 223650_s_at | 0.4901 | 0.1871 | |
| GSE97050 | NRBF2 | 29982 | A_33_P3415895 | 0.1996 | 0.4529 | |
| SRP007169 | NRBF2 | 29982 | RNAseq | -0.2065 | 0.6806 | |
| SRP008496 | NRBF2 | 29982 | RNAseq | -0.3214 | 0.2330 | |
| SRP064894 | NRBF2 | 29982 | RNAseq | -0.0505 | 0.7736 | |
| SRP133303 | NRBF2 | 29982 | RNAseq | 0.6330 | 0.0009 | |
| SRP159526 | NRBF2 | 29982 | RNAseq | -0.4158 | 0.0651 | |
| SRP193095 | NRBF2 | 29982 | RNAseq | -0.0957 | 0.3970 | |
| SRP219564 | NRBF2 | 29982 | RNAseq | -0.1311 | 0.7229 | |
| TCGA | NRBF2 | 29982 | RNAseq | 0.1701 | 0.0134 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NRBF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRBF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRBF2 | 29982 | 3 | 7 | 20 | |
| GSE20123 | NRBF2 | 29982 | 3 | 7 | 20 | |
| GSE43470 | NRBF2 | 29982 | 2 | 5 | 36 | |
| GSE46452 | NRBF2 | 29982 | 0 | 11 | 48 | |
| GSE47630 | NRBF2 | 29982 | 4 | 12 | 24 | |
| GSE54993 | NRBF2 | 29982 | 9 | 0 | 61 | |
| GSE54994 | NRBF2 | 29982 | 4 | 10 | 39 | |
| GSE60625 | NRBF2 | 29982 | 0 | 0 | 11 | |
| GSE74703 | NRBF2 | 29982 | 2 | 3 | 31 | |
| GSE74704 | NRBF2 | 29982 | 2 | 5 | 13 | |
| TCGA | NRBF2 | 29982 | 12 | 22 | 62 |
Total number of gains: 41; Total number of losses: 82; Total Number of normals: 365.
Somatic mutations of NRBF2:
Generating mutation plots.
Highly correlated genes for NRBF2:
Showing top 20/523 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRBF2 | VPS35 | 0.761002 | 4 | 0 | 4 |
| NRBF2 | ABI1 | 0.740809 | 3 | 0 | 3 |
| NRBF2 | ODF2L | 0.722214 | 3 | 0 | 3 |
| NRBF2 | EZH2 | 0.714823 | 3 | 0 | 3 |
| NRBF2 | SEC22A | 0.714331 | 3 | 0 | 3 |
| NRBF2 | AP1AR | 0.708777 | 3 | 0 | 3 |
| NRBF2 | TTC39B | 0.708313 | 3 | 0 | 3 |
| NRBF2 | ATP6V0E1 | 0.707171 | 4 | 0 | 3 |
| NRBF2 | MRPL46 | 0.706986 | 3 | 0 | 3 |
| NRBF2 | XRCC5 | 0.7044 | 4 | 0 | 3 |
| NRBF2 | FAHD1 | 0.693228 | 3 | 0 | 3 |
| NRBF2 | CGRRF1 | 0.691853 | 3 | 0 | 3 |
| NRBF2 | SLC37A3 | 0.684587 | 3 | 0 | 3 |
| NRBF2 | STRN3 | 0.677876 | 4 | 0 | 3 |
| NRBF2 | ALG10 | 0.677577 | 4 | 0 | 4 |
| NRBF2 | FBXO39 | 0.676935 | 3 | 0 | 3 |
| NRBF2 | POLE3 | 0.674949 | 6 | 0 | 5 |
| NRBF2 | SMU1 | 0.672848 | 6 | 0 | 5 |
| NRBF2 | KCMF1 | 0.6726 | 3 | 0 | 3 |
| NRBF2 | JKAMP | 0.669041 | 5 | 0 | 4 |
For details and further investigation, click here
