| Full name: ring finger protein 7 | Alias Symbol: SAG|ROC2|CKBBP1 | ||
| Type: protein-coding gene | Cytoband: 3q23 | ||
| Entrez ID: 9616 | HGNC ID: HGNC:10070 | Ensembl Gene: ENSG00000114125 | OMIM ID: 603863 |
| Drug and gene relationship at DGIdb | |||
Expression of RNF7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RNF7 | 9616 | 224439_x_at | 0.5077 | 0.1476 | |
| GSE20347 | RNF7 | 9616 | 218286_s_at | 0.9468 | 0.0000 | |
| GSE23400 | RNF7 | 9616 | 218286_s_at | 0.7598 | 0.0000 | |
| GSE26886 | RNF7 | 9616 | 224439_x_at | 0.3232 | 0.0225 | |
| GSE29001 | RNF7 | 9616 | 218286_s_at | 0.7548 | 0.0285 | |
| GSE38129 | RNF7 | 9616 | 218286_s_at | 0.8907 | 0.0000 | |
| GSE45670 | RNF7 | 9616 | 218286_s_at | 0.6397 | 0.0009 | |
| GSE53622 | RNF7 | 9616 | 56057 | 0.6666 | 0.0000 | |
| GSE53624 | RNF7 | 9616 | 56057 | 0.8521 | 0.0000 | |
| GSE63941 | RNF7 | 9616 | 224439_x_at | 0.1557 | 0.7323 | |
| GSE77861 | RNF7 | 9616 | 224439_x_at | 0.6818 | 0.0181 | |
| GSE97050 | RNF7 | 9616 | A_23_P109768 | 0.3910 | 0.2243 | |
| SRP007169 | RNF7 | 9616 | RNAseq | 0.6482 | 0.0313 | |
| SRP008496 | RNF7 | 9616 | RNAseq | 1.0400 | 0.0000 | |
| SRP064894 | RNF7 | 9616 | RNAseq | 0.5979 | 0.0177 | |
| SRP133303 | RNF7 | 9616 | RNAseq | 0.6468 | 0.0006 | |
| SRP159526 | RNF7 | 9616 | RNAseq | 0.8841 | 0.0131 | |
| SRP193095 | RNF7 | 9616 | RNAseq | 0.4012 | 0.0214 | |
| SRP219564 | RNF7 | 9616 | RNAseq | 0.2322 | 0.3926 | |
| TCGA | RNF7 | 9616 | RNAseq | 0.2540 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RNF7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RNF7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF7 | 9616 | 20 | 0 | 10 | |
| GSE20123 | RNF7 | 9616 | 20 | 0 | 10 | |
| GSE43470 | RNF7 | 9616 | 22 | 0 | 21 | |
| GSE46452 | RNF7 | 9616 | 15 | 4 | 40 | |
| GSE47630 | RNF7 | 9616 | 19 | 3 | 18 | |
| GSE54993 | RNF7 | 9616 | 1 | 8 | 61 | |
| GSE54994 | RNF7 | 9616 | 34 | 1 | 18 | |
| GSE60625 | RNF7 | 9616 | 0 | 6 | 5 | |
| GSE74703 | RNF7 | 9616 | 19 | 0 | 17 | |
| GSE74704 | RNF7 | 9616 | 14 | 0 | 6 | |
| TCGA | RNF7 | 9616 | 63 | 4 | 29 |
Total number of gains: 227; Total number of losses: 26; Total Number of normals: 235.
Somatic mutations of RNF7:
Generating mutation plots.
Highly correlated genes for RNF7:
Showing top 20/1884 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF7 | ZNF142 | 0.782678 | 3 | 0 | 3 |
| RNF7 | AP2M1 | 0.778667 | 9 | 0 | 9 |
| RNF7 | TRIM59 | 0.76639 | 6 | 0 | 6 |
| RNF7 | ORAI1 | 0.745096 | 4 | 0 | 4 |
| RNF7 | NCBP2 | 0.734988 | 11 | 0 | 10 |
| RNF7 | UCK2 | 0.732007 | 3 | 0 | 3 |
| RNF7 | DVL3 | 0.727153 | 11 | 0 | 10 |
| RNF7 | SLC33A1 | 0.726915 | 11 | 0 | 9 |
| RNF7 | SMARCE1 | 0.726219 | 4 | 0 | 4 |
| RNF7 | MRPL38 | 0.725358 | 3 | 0 | 3 |
| RNF7 | PARL | 0.725334 | 13 | 0 | 12 |
| RNF7 | ATR | 0.724061 | 12 | 0 | 10 |
| RNF7 | U2SURP | 0.723509 | 10 | 0 | 9 |
| RNF7 | GNG10 | 0.723151 | 3 | 0 | 3 |
| RNF7 | RWDD2A | 0.719529 | 3 | 0 | 3 |
| RNF7 | FH | 0.717257 | 3 | 0 | 3 |
| RNF7 | HMCES | 0.71586 | 10 | 0 | 8 |
| RNF7 | UMPS | 0.71551 | 12 | 0 | 10 |
| RNF7 | DUS3L | 0.715034 | 4 | 0 | 3 |
| RNF7 | LEMD2 | 0.715025 | 3 | 0 | 3 |
For details and further investigation, click here
