| Full name: ficolin 1 | Alias Symbol: FCNM | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 2219 | HGNC ID: HGNC:3623 | Ensembl Gene: ENSG00000085265 | OMIM ID: 601252 |
| Drug and gene relationship at DGIdb | |||
Expression of FCN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCN1 | 2219 | 205237_at | -0.0218 | 0.9881 | |
| GSE20347 | FCN1 | 2219 | 205237_at | -0.0714 | 0.3008 | |
| GSE23400 | FCN1 | 2219 | 205237_at | -0.0830 | 0.0166 | |
| GSE26886 | FCN1 | 2219 | 205237_at | -0.1947 | 0.1164 | |
| GSE29001 | FCN1 | 2219 | 205237_at | 0.0155 | 0.9632 | |
| GSE38129 | FCN1 | 2219 | 205237_at | -0.1143 | 0.6100 | |
| GSE45670 | FCN1 | 2219 | 205237_at | -0.0532 | 0.7393 | |
| GSE53622 | FCN1 | 2219 | 72782 | -0.1210 | 0.1446 | |
| GSE53624 | FCN1 | 2219 | 72782 | -0.1860 | 0.0228 | |
| GSE63941 | FCN1 | 2219 | 205237_at | 0.0311 | 0.8437 | |
| GSE77861 | FCN1 | 2219 | 205237_at | -0.0912 | 0.5798 | |
| GSE97050 | FCN1 | 2219 | A_23_P157879 | 0.2781 | 0.3671 | |
| SRP007169 | FCN1 | 2219 | RNAseq | 0.1832 | 0.7753 | |
| SRP064894 | FCN1 | 2219 | RNAseq | -0.0297 | 0.9446 | |
| SRP133303 | FCN1 | 2219 | RNAseq | 0.0436 | 0.8589 | |
| SRP159526 | FCN1 | 2219 | RNAseq | 1.6771 | 0.0046 | |
| SRP193095 | FCN1 | 2219 | RNAseq | 0.5972 | 0.0028 | |
| SRP219564 | FCN1 | 2219 | RNAseq | 1.2501 | 0.0229 | |
| TCGA | FCN1 | 2219 | RNAseq | -0.7579 | 0.0877 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FCN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCN1 | 2219 | 4 | 7 | 19 | |
| GSE20123 | FCN1 | 2219 | 4 | 7 | 19 | |
| GSE43470 | FCN1 | 2219 | 3 | 8 | 32 | |
| GSE46452 | FCN1 | 2219 | 6 | 13 | 40 | |
| GSE47630 | FCN1 | 2219 | 6 | 15 | 19 | |
| GSE54993 | FCN1 | 2219 | 3 | 3 | 64 | |
| GSE54994 | FCN1 | 2219 | 11 | 9 | 33 | |
| GSE60625 | FCN1 | 2219 | 0 | 0 | 11 | |
| GSE74703 | FCN1 | 2219 | 3 | 6 | 27 | |
| GSE74704 | FCN1 | 2219 | 2 | 5 | 13 | |
| TCGA | FCN1 | 2219 | 28 | 25 | 43 |
Total number of gains: 70; Total number of losses: 98; Total Number of normals: 320.
Somatic mutations of FCN1:
Generating mutation plots.
Highly correlated genes for FCN1:
Showing top 20/129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCN1 | STAC2 | 0.665375 | 3 | 0 | 3 |
| FCN1 | THEMIS2 | 0.65207 | 4 | 0 | 4 |
| FCN1 | MOBP | 0.647559 | 3 | 0 | 3 |
| FCN1 | COMP | 0.644113 | 4 | 0 | 4 |
| FCN1 | PRDM8 | 0.64155 | 3 | 0 | 3 |
| FCN1 | PLA2G4D | 0.631201 | 3 | 0 | 3 |
| FCN1 | PLCL2 | 0.628592 | 4 | 0 | 3 |
| FCN1 | RGS16 | 0.628577 | 4 | 0 | 3 |
| FCN1 | LINC01215 | 0.627284 | 3 | 0 | 3 |
| FCN1 | C22orf31 | 0.625373 | 3 | 0 | 3 |
| FCN1 | GJA4 | 0.624038 | 5 | 0 | 4 |
| FCN1 | TSPAN33 | 0.621401 | 3 | 0 | 3 |
| FCN1 | CCRL2 | 0.621347 | 3 | 0 | 3 |
| FCN1 | LCN15 | 0.614299 | 3 | 0 | 3 |
| FCN1 | TBXAS1 | 0.611612 | 7 | 0 | 5 |
| FCN1 | HCST | 0.607117 | 4 | 0 | 3 |
| FCN1 | CCL13 | 0.605424 | 4 | 0 | 4 |
| FCN1 | CD40LG | 0.605132 | 3 | 0 | 3 |
| FCN1 | BATF3 | 0.593918 | 3 | 0 | 3 |
| FCN1 | HLA-DOA | 0.591956 | 5 | 0 | 4 |
For details and further investigation, click here
