| Full name: myelin associated oligodendrocyte basic protein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 4336 | HGNC ID: HGNC:7189 | Ensembl Gene: ENSG00000168314 | OMIM ID: 600948 |
| Drug and gene relationship at DGIdb | |||
Expression of MOBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MOBP | 4336 | 235794_at | -0.1213 | 0.6363 | |
| GSE20347 | MOBP | 4336 | 207659_s_at | 0.0202 | 0.7490 | |
| GSE23400 | MOBP | 4336 | 207659_s_at | -0.0264 | 0.3411 | |
| GSE26886 | MOBP | 4336 | 235794_at | 0.1828 | 0.0398 | |
| GSE29001 | MOBP | 4336 | 207659_s_at | -0.2000 | 0.1585 | |
| GSE38129 | MOBP | 4336 | 207659_s_at | -0.0399 | 0.5855 | |
| GSE45670 | MOBP | 4336 | 235794_at | -0.0111 | 0.9071 | |
| GSE53622 | MOBP | 4336 | 36117 | -0.5104 | 0.0000 | |
| GSE53624 | MOBP | 4336 | 12465 | 0.3093 | 0.0021 | |
| GSE63941 | MOBP | 4336 | 210193_at | 0.0370 | 0.8209 | |
| GSE77861 | MOBP | 4336 | 241717_at | -0.1334 | 0.2924 | |
| SRP133303 | MOBP | 4336 | RNAseq | 0.1281 | 0.5821 | |
| SRP193095 | MOBP | 4336 | RNAseq | -0.0891 | 0.5942 | |
| SRP219564 | MOBP | 4336 | RNAseq | 0.6006 | 0.2924 | |
| TCGA | MOBP | 4336 | RNAseq | 2.7185 | 0.0021 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by MOBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MOBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MOBP | 4336 | 0 | 19 | 11 | |
| GSE20123 | MOBP | 4336 | 0 | 19 | 11 | |
| GSE43470 | MOBP | 4336 | 0 | 20 | 23 | |
| GSE46452 | MOBP | 4336 | 2 | 17 | 40 | |
| GSE47630 | MOBP | 4336 | 1 | 25 | 14 | |
| GSE54993 | MOBP | 4336 | 7 | 2 | 61 | |
| GSE54994 | MOBP | 4336 | 0 | 34 | 19 | |
| GSE60625 | MOBP | 4336 | 5 | 0 | 6 | |
| GSE74703 | MOBP | 4336 | 0 | 16 | 20 | |
| GSE74704 | MOBP | 4336 | 0 | 13 | 7 | |
| TCGA | MOBP | 4336 | 1 | 71 | 24 |
Total number of gains: 16; Total number of losses: 236; Total Number of normals: 236.
Somatic mutations of MOBP:
Generating mutation plots.
Highly correlated genes for MOBP:
Showing top 20/443 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MOBP | NUDT7 | 0.695614 | 3 | 0 | 3 |
| MOBP | CPA1 | 0.671986 | 3 | 0 | 3 |
| MOBP | CAPN11 | 0.669178 | 5 | 0 | 4 |
| MOBP | GAD2 | 0.667996 | 3 | 0 | 3 |
| MOBP | PAX7 | 0.66565 | 4 | 0 | 3 |
| MOBP | RPL27A | 0.66224 | 3 | 0 | 3 |
| MOBP | CIITA | 0.649387 | 4 | 0 | 3 |
| MOBP | SLC4A1 | 0.648521 | 5 | 0 | 5 |
| MOBP | FCN1 | 0.647559 | 3 | 0 | 3 |
| MOBP | ACR | 0.645749 | 4 | 0 | 3 |
| MOBP | ARHGEF38 | 0.645173 | 4 | 0 | 4 |
| MOBP | CCL24 | 0.640372 | 3 | 0 | 3 |
| MOBP | KLF1 | 0.640148 | 3 | 0 | 3 |
| MOBP | RHO | 0.637002 | 5 | 0 | 5 |
| MOBP | AMBN | 0.636904 | 5 | 0 | 5 |
| MOBP | SLC22A14 | 0.636809 | 5 | 0 | 4 |
| MOBP | LRRC29 | 0.63567 | 3 | 0 | 3 |
| MOBP | NTRK3 | 0.635543 | 4 | 0 | 3 |
| MOBP | ATOH1 | 0.634373 | 4 | 0 | 4 |
| MOBP | OR6A2 | 0.634122 | 5 | 0 | 3 |
For details and further investigation, click here
