| Full name: C-C motif chemokine receptor like 2 | Alias Symbol: HCR|CRAM-B|CKRX|CRAM-A|ACKR5 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 9034 | HGNC ID: HGNC:1612 | Ensembl Gene: ENSG00000121797 | OMIM ID: 608379 |
| Drug and gene relationship at DGIdb | |||
Expression of CCRL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCRL2 | 9034 | 211434_s_at | 0.5803 | 0.4262 | |
| GSE20347 | CCRL2 | 9034 | 211434_s_at | 0.0838 | 0.2928 | |
| GSE23400 | CCRL2 | 9034 | 211434_s_at | -0.0557 | 0.2688 | |
| GSE26886 | CCRL2 | 9034 | 211434_s_at | 0.1969 | 0.0919 | |
| GSE29001 | CCRL2 | 9034 | 211434_s_at | 0.2326 | 0.2883 | |
| GSE38129 | CCRL2 | 9034 | 211434_s_at | 0.1298 | 0.2302 | |
| GSE45670 | CCRL2 | 9034 | 211434_s_at | 0.0729 | 0.7045 | |
| GSE53622 | CCRL2 | 9034 | 120241 | 0.8519 | 0.0000 | |
| GSE53624 | CCRL2 | 9034 | 120241 | 0.9085 | 0.0000 | |
| GSE63941 | CCRL2 | 9034 | 211434_s_at | 0.3231 | 0.0869 | |
| GSE77861 | CCRL2 | 9034 | 211434_s_at | -0.0896 | 0.5491 | |
| GSE97050 | CCRL2 | 9034 | A_23_P69310 | 0.1813 | 0.5949 | |
| SRP007169 | CCRL2 | 9034 | RNAseq | 3.7212 | 0.0025 | |
| SRP064894 | CCRL2 | 9034 | RNAseq | 1.7565 | 0.0000 | |
| SRP133303 | CCRL2 | 9034 | RNAseq | 1.6990 | 0.0000 | |
| SRP159526 | CCRL2 | 9034 | RNAseq | 0.7439 | 0.3205 | |
| SRP219564 | CCRL2 | 9034 | RNAseq | 0.9916 | 0.0383 | |
| TCGA | CCRL2 | 9034 | RNAseq | -0.3028 | 0.1103 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CCRL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCRL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCRL2 | 9034 | 0 | 17 | 13 | |
| GSE20123 | CCRL2 | 9034 | 0 | 18 | 12 | |
| GSE43470 | CCRL2 | 9034 | 0 | 20 | 23 | |
| GSE46452 | CCRL2 | 9034 | 2 | 17 | 40 | |
| GSE47630 | CCRL2 | 9034 | 2 | 23 | 15 | |
| GSE54993 | CCRL2 | 9034 | 7 | 2 | 61 | |
| GSE54994 | CCRL2 | 9034 | 0 | 36 | 17 | |
| GSE60625 | CCRL2 | 9034 | 5 | 0 | 6 | |
| GSE74703 | CCRL2 | 9034 | 0 | 15 | 21 | |
| GSE74704 | CCRL2 | 9034 | 0 | 12 | 8 |
Total number of gains: 16; Total number of losses: 160; Total Number of normals: 216.
Somatic mutations of CCRL2:
Generating mutation plots.
Highly correlated genes for CCRL2:
Showing top 20/579 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCRL2 | FCGR3A | 0.796039 | 3 | 0 | 3 |
| CCRL2 | GPR84 | 0.744392 | 4 | 0 | 4 |
| CCRL2 | C19orf38 | 0.740565 | 3 | 0 | 3 |
| CCRL2 | MNDA | 0.729331 | 8 | 0 | 8 |
| CCRL2 | C5AR1 | 0.717362 | 8 | 0 | 8 |
| CCRL2 | CLEC4A | 0.715852 | 8 | 0 | 7 |
| CCRL2 | FKBP10 | 0.708617 | 4 | 0 | 4 |
| CCRL2 | GDF9 | 0.708603 | 3 | 0 | 3 |
| CCRL2 | FCGR2C | 0.702747 | 3 | 0 | 3 |
| CCRL2 | LCP2 | 0.695327 | 10 | 0 | 8 |
| CCRL2 | GAGE1 | 0.695144 | 3 | 0 | 3 |
| CCRL2 | CCR1 | 0.694612 | 9 | 0 | 8 |
| CCRL2 | GPR141 | 0.693948 | 3 | 0 | 3 |
| CCRL2 | BCL2A1 | 0.690851 | 8 | 0 | 6 |
| CCRL2 | KLRG1 | 0.690117 | 3 | 0 | 3 |
| CCRL2 | KTI12 | 0.68842 | 3 | 0 | 3 |
| CCRL2 | LILRB2 | 0.683676 | 10 | 0 | 9 |
| CCRL2 | RAB42 | 0.681379 | 3 | 0 | 3 |
| CCRL2 | SAMSN1 | 0.680324 | 8 | 0 | 7 |
| CCRL2 | PIK3AP1 | 0.678206 | 5 | 0 | 4 |
For details and further investigation, click here
