| Full name: regulator of G protein signaling 16 | Alias Symbol: A28-RGS14|RGS-r | ||
| Type: protein-coding gene | Cytoband: 1q25.3 | ||
| Entrez ID: 6004 | HGNC ID: HGNC:9997 | Ensembl Gene: ENSG00000143333 | OMIM ID: 602514 |
| Drug and gene relationship at DGIdb | |||
Expression of RGS16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGS16 | 6004 | 209324_s_at | 0.7904 | 0.4002 | |
| GSE20347 | RGS16 | 6004 | 209325_s_at | 0.4729 | 0.0000 | |
| GSE23400 | RGS16 | 6004 | 209325_s_at | 0.3073 | 0.0000 | |
| GSE26886 | RGS16 | 6004 | 209325_s_at | 0.4951 | 0.0014 | |
| GSE29001 | RGS16 | 6004 | 209325_s_at | 0.1352 | 0.5842 | |
| GSE38129 | RGS16 | 6004 | 209324_s_at | 0.6611 | 0.0192 | |
| GSE45670 | RGS16 | 6004 | 209324_s_at | -0.0801 | 0.7669 | |
| GSE53622 | RGS16 | 6004 | 44256 | 1.0640 | 0.0000 | |
| GSE53624 | RGS16 | 6004 | 44256 | 1.3556 | 0.0000 | |
| GSE63941 | RGS16 | 6004 | 209325_s_at | 0.6303 | 0.1207 | |
| GSE77861 | RGS16 | 6004 | 209324_s_at | 0.0864 | 0.4731 | |
| GSE97050 | RGS16 | 6004 | A_23_P217845 | 0.1563 | 0.8055 | |
| SRP007169 | RGS16 | 6004 | RNAseq | 2.2641 | 0.0001 | |
| SRP008496 | RGS16 | 6004 | RNAseq | 2.6760 | 0.0000 | |
| SRP064894 | RGS16 | 6004 | RNAseq | 1.9145 | 0.0000 | |
| SRP133303 | RGS16 | 6004 | RNAseq | 1.8314 | 0.0000 | |
| SRP159526 | RGS16 | 6004 | RNAseq | 1.8802 | 0.0000 | |
| SRP193095 | RGS16 | 6004 | RNAseq | 1.3942 | 0.0000 | |
| SRP219564 | RGS16 | 6004 | RNAseq | 0.9881 | 0.2234 | |
| TCGA | RGS16 | 6004 | RNAseq | 0.4058 | 0.0058 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by RGS16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RGS16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGS16 | 6004 | 12 | 0 | 18 | |
| GSE20123 | RGS16 | 6004 | 12 | 0 | 18 | |
| GSE43470 | RGS16 | 6004 | 7 | 1 | 35 | |
| GSE46452 | RGS16 | 6004 | 3 | 1 | 55 | |
| GSE47630 | RGS16 | 6004 | 14 | 0 | 26 | |
| GSE54993 | RGS16 | 6004 | 0 | 6 | 64 | |
| GSE54994 | RGS16 | 6004 | 15 | 0 | 38 | |
| GSE60625 | RGS16 | 6004 | 0 | 0 | 11 | |
| GSE74703 | RGS16 | 6004 | 7 | 1 | 28 | |
| GSE74704 | RGS16 | 6004 | 5 | 0 | 15 | |
| TCGA | RGS16 | 6004 | 40 | 3 | 53 |
Total number of gains: 115; Total number of losses: 12; Total Number of normals: 361.
Somatic mutations of RGS16:
Generating mutation plots.
Highly correlated genes for RGS16:
Showing top 20/343 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGS16 | BRF1 | 0.671092 | 3 | 0 | 3 |
| RGS16 | AGAP2 | 0.664315 | 3 | 0 | 3 |
| RGS16 | HAGLROS | 0.65654 | 3 | 0 | 3 |
| RGS16 | FAM219A | 0.650019 | 3 | 0 | 3 |
| RGS16 | TFEB | 0.6481 | 4 | 0 | 3 |
| RGS16 | BCORL1 | 0.64622 | 5 | 0 | 4 |
| RGS16 | YBX1 | 0.64621 | 3 | 0 | 3 |
| RGS16 | KSR2 | 0.641164 | 3 | 0 | 3 |
| RGS16 | ITGA11 | 0.637675 | 3 | 0 | 3 |
| RGS16 | C19orf12 | 0.637572 | 3 | 0 | 3 |
| RGS16 | RBFOX1 | 0.636635 | 3 | 0 | 3 |
| RGS16 | ZNF281 | 0.631894 | 6 | 0 | 5 |
| RGS16 | FCN1 | 0.628577 | 4 | 0 | 3 |
| RGS16 | BLM | 0.625061 | 3 | 0 | 3 |
| RGS16 | CSMD2 | 0.623165 | 3 | 0 | 3 |
| RGS16 | ICAM2 | 0.621981 | 3 | 0 | 3 |
| RGS16 | STX1A | 0.620412 | 5 | 0 | 5 |
| RGS16 | GLIS2 | 0.619052 | 4 | 0 | 4 |
| RGS16 | RGS3 | 0.618815 | 8 | 0 | 7 |
| RGS16 | LZTR1 | 0.613978 | 7 | 0 | 5 |
For details and further investigation, click here
