| Full name: NFU1 iron-sulfur cluster scaffold | Alias Symbol: CGI-33|NifU|NIFUC | ||
| Type: protein-coding gene | Cytoband: 2p13.3 | ||
| Entrez ID: 27247 | HGNC ID: HGNC:16287 | Ensembl Gene: ENSG00000169599 | OMIM ID: 608100 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NFU1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFU1 | 27247 | 218946_at | -0.5753 | 0.4150 | |
| GSE20347 | NFU1 | 27247 | 218946_at | 0.1054 | 0.7035 | |
| GSE23400 | NFU1 | 27247 | 218946_at | 0.1753 | 0.0129 | |
| GSE26886 | NFU1 | 27247 | 218946_at | 0.3232 | 0.2140 | |
| GSE29001 | NFU1 | 27247 | 218946_at | 0.1075 | 0.7593 | |
| GSE38129 | NFU1 | 27247 | 218946_at | -0.0329 | 0.8970 | |
| GSE45670 | NFU1 | 27247 | 218946_at | 0.0674 | 0.7341 | |
| GSE53622 | NFU1 | 27247 | 98520 | -0.0632 | 0.3365 | |
| GSE53624 | NFU1 | 27247 | 98520 | 0.0927 | 0.0589 | |
| GSE63941 | NFU1 | 27247 | 218946_at | -0.1620 | 0.7547 | |
| GSE77861 | NFU1 | 27247 | 218946_at | 0.3443 | 0.2355 | |
| GSE97050 | NFU1 | 27247 | A_23_P147296 | -0.2021 | 0.4637 | |
| SRP007169 | NFU1 | 27247 | RNAseq | -0.7597 | 0.0486 | |
| SRP008496 | NFU1 | 27247 | RNAseq | -0.5366 | 0.0370 | |
| SRP064894 | NFU1 | 27247 | RNAseq | 0.1214 | 0.5331 | |
| SRP133303 | NFU1 | 27247 | RNAseq | 0.2397 | 0.0527 | |
| SRP159526 | NFU1 | 27247 | RNAseq | 0.1122 | 0.6936 | |
| SRP193095 | NFU1 | 27247 | RNAseq | -0.1820 | 0.2158 | |
| SRP219564 | NFU1 | 27247 | RNAseq | -0.1632 | 0.6934 | |
| TCGA | NFU1 | 27247 | RNAseq | -0.0806 | 0.1673 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NFU1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFU1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFU1 | 27247 | 11 | 0 | 19 | |
| GSE20123 | NFU1 | 27247 | 11 | 0 | 19 | |
| GSE43470 | NFU1 | 27247 | 5 | 0 | 38 | |
| GSE46452 | NFU1 | 27247 | 2 | 3 | 54 | |
| GSE47630 | NFU1 | 27247 | 7 | 0 | 33 | |
| GSE54993 | NFU1 | 27247 | 0 | 6 | 64 | |
| GSE54994 | NFU1 | 27247 | 12 | 0 | 41 | |
| GSE60625 | NFU1 | 27247 | 0 | 3 | 8 | |
| GSE74703 | NFU1 | 27247 | 5 | 0 | 31 | |
| GSE74704 | NFU1 | 27247 | 9 | 0 | 11 | |
| TCGA | NFU1 | 27247 | 36 | 2 | 58 |
Total number of gains: 98; Total number of losses: 14; Total Number of normals: 376.
Somatic mutations of NFU1:
Generating mutation plots.
Highly correlated genes for NFU1:
Showing top 20/358 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFU1 | EIF2B4 | 0.701254 | 3 | 0 | 3 |
| NFU1 | AEBP2 | 0.700695 | 3 | 0 | 3 |
| NFU1 | HSPA9 | 0.699215 | 3 | 0 | 3 |
| NFU1 | FHOD3 | 0.698694 | 4 | 0 | 4 |
| NFU1 | WDR92 | 0.692716 | 3 | 0 | 3 |
| NFU1 | RTN3 | 0.687627 | 3 | 0 | 3 |
| NFU1 | ZDHHC2 | 0.68645 | 3 | 0 | 3 |
| NFU1 | CDNF | 0.673547 | 4 | 0 | 3 |
| NFU1 | MRPL39 | 0.668203 | 3 | 0 | 3 |
| NFU1 | PACSIN2 | 0.666128 | 4 | 0 | 3 |
| NFU1 | DCTN4 | 0.665737 | 4 | 0 | 3 |
| NFU1 | NDUFS4 | 0.665621 | 4 | 0 | 4 |
| NFU1 | MYH3 | 0.65525 | 3 | 0 | 3 |
| NFU1 | SNX13 | 0.654404 | 4 | 0 | 3 |
| NFU1 | COMMD10 | 0.64725 | 5 | 0 | 4 |
| NFU1 | SKAP2 | 0.644386 | 4 | 0 | 3 |
| NFU1 | ATL2 | 0.643805 | 4 | 0 | 3 |
| NFU1 | RBKS | 0.642411 | 3 | 0 | 3 |
| NFU1 | COMMD1 | 0.641391 | 4 | 0 | 3 |
| NFU1 | CYCS | 0.641183 | 4 | 0 | 3 |
For details and further investigation, click here
