| Full name: FCF1 rRNA-processing protein | Alias Symbol: CGI-35|Bka|UTP24 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 51077 | HGNC ID: HGNC:20220 | Ensembl Gene: ENSG00000119616 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FCF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FCF1 | 51077 | 240928_at | 0.3301 | 0.5397 | |
| GSE20347 | FCF1 | 51077 | 215567_at | 0.4382 | 0.0429 | |
| GSE23400 | FCF1 | 51077 | 215567_at | 0.1212 | 0.0001 | |
| GSE26886 | FCF1 | 51077 | 240928_at | 0.3141 | 0.0978 | |
| GSE29001 | FCF1 | 51077 | 215567_at | 0.7171 | 0.0035 | |
| GSE38129 | FCF1 | 51077 | 215567_at | 0.3395 | 0.1739 | |
| GSE45670 | FCF1 | 51077 | 240928_at | 0.2900 | 0.0715 | |
| GSE53622 | FCF1 | 51077 | 27793 | 0.6547 | 0.0000 | |
| GSE53624 | FCF1 | 51077 | 121524 | 0.7106 | 0.0000 | |
| GSE63941 | FCF1 | 51077 | 219927_at | 3.1879 | 0.0000 | |
| GSE77861 | FCF1 | 51077 | 240928_at | -0.0837 | 0.3681 | |
| GSE97050 | FCF1 | 51077 | A_33_P3264505 | 0.1526 | 0.6478 | |
| SRP007169 | FCF1 | 51077 | RNAseq | 0.2718 | 0.4232 | |
| SRP008496 | FCF1 | 51077 | RNAseq | 0.2471 | 0.1936 | |
| SRP064894 | FCF1 | 51077 | RNAseq | 0.4380 | 0.0114 | |
| SRP133303 | FCF1 | 51077 | RNAseq | 0.4874 | 0.0000 | |
| SRP159526 | FCF1 | 51077 | RNAseq | 0.0589 | 0.8460 | |
| SRP193095 | FCF1 | 51077 | RNAseq | 0.1420 | 0.0950 | |
| SRP219564 | FCF1 | 51077 | RNAseq | 0.2242 | 0.5516 | |
| TCGA | FCF1 | 51077 | RNAseq | 0.1888 | 0.0005 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by FCF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FCF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FCF1 | 51077 | 8 | 3 | 19 | |
| GSE20123 | FCF1 | 51077 | 8 | 3 | 19 | |
| GSE43470 | FCF1 | 51077 | 8 | 3 | 32 | |
| GSE46452 | FCF1 | 51077 | 16 | 3 | 40 | |
| GSE47630 | FCF1 | 51077 | 11 | 8 | 21 | |
| GSE54993 | FCF1 | 51077 | 3 | 8 | 59 | |
| GSE54994 | FCF1 | 51077 | 19 | 4 | 30 | |
| GSE60625 | FCF1 | 51077 | 0 | 2 | 9 | |
| GSE74703 | FCF1 | 51077 | 7 | 3 | 26 | |
| GSE74704 | FCF1 | 51077 | 3 | 3 | 14 | |
| TCGA | FCF1 | 51077 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of FCF1:
Generating mutation plots.
Highly correlated genes for FCF1:
Showing top 20/591 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FCF1 | RNASEH2B | 0.809443 | 3 | 0 | 3 |
| FCF1 | FKBPL | 0.797961 | 3 | 0 | 3 |
| FCF1 | FBXO11 | 0.774359 | 3 | 0 | 3 |
| FCF1 | DICER1 | 0.774238 | 5 | 0 | 4 |
| FCF1 | TRADD | 0.766575 | 3 | 0 | 3 |
| FCF1 | LRRC40 | 0.760506 | 3 | 0 | 3 |
| FCF1 | EIF3C | 0.75679 | 3 | 0 | 3 |
| FCF1 | CHD7 | 0.744772 | 3 | 0 | 3 |
| FCF1 | GRHL2 | 0.743369 | 3 | 0 | 3 |
| FCF1 | VGLL4 | 0.729635 | 3 | 0 | 3 |
| FCF1 | BAG6 | 0.728771 | 3 | 0 | 3 |
| FCF1 | EXOSC8 | 0.728411 | 4 | 0 | 3 |
| FCF1 | CTDSPL2 | 0.718534 | 3 | 0 | 3 |
| FCF1 | EBNA1BP2 | 0.715844 | 3 | 0 | 3 |
| FCF1 | E2F8 | 0.714465 | 3 | 0 | 3 |
| FCF1 | STRN4 | 0.712514 | 3 | 0 | 3 |
| FCF1 | BORA | 0.712058 | 4 | 0 | 4 |
| FCF1 | ZNF740 | 0.709713 | 3 | 0 | 3 |
| FCF1 | PPP2R5E | 0.706428 | 4 | 0 | 4 |
| FCF1 | SETD3 | 0.705578 | 3 | 0 | 3 |
For details and further investigation, click here
