| Full name: NIPA like domain containing 4 | Alias Symbol: ICHYN | ||
| Type: protein-coding gene | Cytoband: 5q33.3 | ||
| Entrez ID: 348938 | HGNC ID: HGNC:28018 | Ensembl Gene: ENSG00000172548 | OMIM ID: 609383 |
| Drug and gene relationship at DGIdb | |||
Expression of NIPAL4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NIPAL4 | 348938 | 230188_at | 0.3323 | 0.7501 | |
| GSE26886 | NIPAL4 | 348938 | 230188_at | -0.9607 | 0.0300 | |
| GSE45670 | NIPAL4 | 348938 | 230188_at | 0.8214 | 0.0067 | |
| GSE63941 | NIPAL4 | 348938 | 230188_at | 0.7473 | 0.0609 | |
| GSE77861 | NIPAL4 | 348938 | 230188_at | 0.4561 | 0.2084 | |
| GSE97050 | NIPAL4 | 348938 | A_33_P3415052 | 0.2451 | 0.6110 | |
| SRP007169 | NIPAL4 | 348938 | RNAseq | -0.4671 | 0.6579 | |
| SRP008496 | NIPAL4 | 348938 | RNAseq | -0.8414 | 0.3132 | |
| SRP064894 | NIPAL4 | 348938 | RNAseq | 0.4440 | 0.2765 | |
| SRP133303 | NIPAL4 | 348938 | RNAseq | 0.3093 | 0.5108 | |
| SRP159526 | NIPAL4 | 348938 | RNAseq | -1.1193 | 0.0312 | |
| SRP219564 | NIPAL4 | 348938 | RNAseq | 0.3530 | 0.7209 | |
| TCGA | NIPAL4 | 348938 | RNAseq | 1.0441 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by NIPAL4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of NIPAL4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NIPAL4 | 348938 | 0 | 11 | 19 | |
| GSE20123 | NIPAL4 | 348938 | 0 | 11 | 19 | |
| GSE43470 | NIPAL4 | 348938 | 2 | 11 | 30 | |
| GSE46452 | NIPAL4 | 348938 | 0 | 27 | 32 | |
| GSE47630 | NIPAL4 | 348938 | 0 | 20 | 20 | |
| GSE54993 | NIPAL4 | 348938 | 9 | 1 | 60 | |
| GSE54994 | NIPAL4 | 348938 | 1 | 16 | 36 | |
| GSE60625 | NIPAL4 | 348938 | 0 | 0 | 11 | |
| GSE74703 | NIPAL4 | 348938 | 2 | 8 | 26 | |
| GSE74704 | NIPAL4 | 348938 | 0 | 6 | 14 | |
| TCGA | NIPAL4 | 348938 | 5 | 36 | 55 |
Total number of gains: 19; Total number of losses: 147; Total Number of normals: 322.
Somatic mutations of NIPAL4:
Generating mutation plots.
Highly correlated genes for NIPAL4:
Showing top 20/288 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NIPAL4 | SCAMP1 | 0.740231 | 3 | 0 | 3 |
| NIPAL4 | CEACAM19 | 0.73407 | 4 | 0 | 4 |
| NIPAL4 | PNP | 0.727386 | 5 | 0 | 5 |
| NIPAL4 | TUBA4B | 0.72051 | 3 | 0 | 3 |
| NIPAL4 | SLC4A1AP | 0.699841 | 3 | 0 | 3 |
| NIPAL4 | FLVCR2 | 0.688208 | 3 | 0 | 3 |
| NIPAL4 | UBLCP1 | 0.686007 | 4 | 0 | 4 |
| NIPAL4 | MMP14 | 0.66813 | 3 | 0 | 3 |
| NIPAL4 | TRADD | 0.665339 | 4 | 0 | 4 |
| NIPAL4 | CERCAM | 0.66302 | 3 | 0 | 3 |
| NIPAL4 | NSFL1C | 0.659991 | 4 | 0 | 3 |
| NIPAL4 | GSDMC | 0.658257 | 5 | 0 | 5 |
| NIPAL4 | ARL6IP6 | 0.65645 | 3 | 0 | 3 |
| NIPAL4 | STK17A | 0.65328 | 4 | 0 | 4 |
| NIPAL4 | RAB13 | 0.65133 | 3 | 0 | 3 |
| NIPAL4 | CA2 | 0.646888 | 4 | 0 | 3 |
| NIPAL4 | SGPP1 | 0.645327 | 4 | 0 | 3 |
| NIPAL4 | SFN | 0.645009 | 7 | 0 | 5 |
| NIPAL4 | ISCA2 | 0.64273 | 3 | 0 | 3 |
| NIPAL4 | AKR1C1 | 0.642427 | 3 | 0 | 3 |
For details and further investigation, click here
