TAS2R38

 

Full name: taste 2 receptor member 38 Alias Symbol: T2R61
Type: protein-coding gene Cytoband: 7q34
Entrez ID: 5726 HGNC ID: HGNC:9584 Ensembl Gene: ENSG00000257138 OMIM ID: 607751
Drug and gene relationship at DGIdb

 

Expression of TAS2R38:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TAS2R38 5726 1553555_at -0.0663 0.7985
GSE26886 TAS2R38 5726 1553555_at -0.1464 0.0849
GSE45670 TAS2R38 5726 1553555_at 0.1971 0.0214
GSE53622 TAS2R38 5726 22450 0.4864 0.0018
GSE53624 TAS2R38 5726 22450 0.4149 0.0348
GSE63941 TAS2R38 5726 1553555_at -0.0984 0.4676
GSE77861 TAS2R38 5726 1553555_at -0.0913 0.2652
GSE97050 TAS2R38 5726 A_23_P359746 -0.0412 0.8840
TCGA TAS2R38 5726 RNAseq 4.1102 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by TAS2R38 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TAS2R38:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TAS2R38 5726 5 2 23
GSE20123 TAS2R38 5726 5 2 23
GSE43470 TAS2R38 5726 2 4 37
GSE46452 TAS2R38 5726 7 2 50
GSE47630 TAS2R38 5726 6 7 27
GSE54993 TAS2R38 5726 3 5 62
GSE54994 TAS2R38 5726 5 8 40
GSE60625 TAS2R38 5726 0 0 11
GSE74703 TAS2R38 5726 2 4 30
GSE74704 TAS2R38 5726 1 2 17
TCGA TAS2R38 5726 29 23 44

Total number of gains: 65; Total number of losses: 59; Total Number of normals: 364.  


 

Somatic mutations of TAS2R38:

 

Generating mutation plots.

 

Highly correlated genes for TAS2R38:

 

Showing top 20/67 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TAS2R38TBC1D150.707655303
TAS2R38CCDC1540.695301303
TAS2R38KLF140.681226403
TAS2R38DNAH10.678552303
TAS2R38GRIA40.676271303
TAS2R38AJAP10.676246403
TAS2R38AKR1E20.675926403
TAS2R38PODN0.670089303
TAS2R38PORCN0.653929303
TAS2R38IER30.645178303
TAS2R38FLVCR20.642122303
TAS2R38SRR0.639618303
TAS2R38OR2B20.631706303
TAS2R38PDE10A0.630838303
TAS2R38ZNF6190.625268504
TAS2R38CASC60.61865303
TAS2R38RAPGEF30.618182303
TAS2R38EHD10.617535403
TAS2R38CTXN10.617081303
TAS2R38SAMD150.610224504

For details and further investigation, click here