| Full name: ribokinase | Alias Symbol: DKFZp686G13268|RBSK | ||
| Type: protein-coding gene | Cytoband: 2p23.2 | ||
| Entrez ID: 64080 | HGNC ID: HGNC:30325 | Ensembl Gene: ENSG00000171174 | OMIM ID: 611132 |
| Drug and gene relationship at DGIdb | |||
Expression of RBKS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RBKS | 64080 | 219222_at | -0.1693 | 0.6938 | |
| GSE20347 | RBKS | 64080 | 219222_at | -0.4743 | 0.0002 | |
| GSE23400 | RBKS | 64080 | 219222_at | -0.1287 | 0.0154 | |
| GSE26886 | RBKS | 64080 | 219222_at | -0.5408 | 0.0293 | |
| GSE29001 | RBKS | 64080 | 57540_at | -0.7945 | 0.0100 | |
| GSE38129 | RBKS | 64080 | 219222_at | -0.2981 | 0.0219 | |
| GSE45670 | RBKS | 64080 | 219222_at | -0.0338 | 0.8962 | |
| GSE53622 | RBKS | 64080 | 1778 | -0.0713 | 0.4473 | |
| GSE53624 | RBKS | 64080 | 1778 | -0.5414 | 0.0000 | |
| GSE63941 | RBKS | 64080 | 219222_at | 0.0696 | 0.9152 | |
| GSE77861 | RBKS | 64080 | 57540_at | -0.5837 | 0.0091 | |
| GSE97050 | RBKS | 64080 | A_23_P9523 | 0.1487 | 0.4815 | |
| SRP007169 | RBKS | 64080 | RNAseq | -2.1917 | 0.0062 | |
| SRP064894 | RBKS | 64080 | RNAseq | -0.4391 | 0.0571 | |
| SRP133303 | RBKS | 64080 | RNAseq | -0.2303 | 0.1613 | |
| SRP159526 | RBKS | 64080 | RNAseq | -0.5641 | 0.0614 | |
| SRP193095 | RBKS | 64080 | RNAseq | -0.8900 | 0.0000 | |
| SRP219564 | RBKS | 64080 | RNAseq | -0.7837 | 0.0228 | |
| TCGA | RBKS | 64080 | RNAseq | 0.1663 | 0.1561 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RBKS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RBKS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RBKS | 64080 | 11 | 2 | 17 | |
| GSE20123 | RBKS | 64080 | 11 | 2 | 17 | |
| GSE43470 | RBKS | 64080 | 3 | 1 | 39 | |
| GSE46452 | RBKS | 64080 | 2 | 4 | 53 | |
| GSE47630 | RBKS | 64080 | 8 | 0 | 32 | |
| GSE54993 | RBKS | 64080 | 0 | 6 | 64 | |
| GSE54994 | RBKS | 64080 | 10 | 0 | 43 | |
| GSE60625 | RBKS | 64080 | 0 | 3 | 8 | |
| GSE74703 | RBKS | 64080 | 3 | 0 | 33 | |
| GSE74704 | RBKS | 64080 | 9 | 1 | 10 | |
| TCGA | RBKS | 64080 | 36 | 2 | 58 |
Total number of gains: 93; Total number of losses: 21; Total Number of normals: 374.
Somatic mutations of RBKS:
Generating mutation plots.
Highly correlated genes for RBKS:
Showing top 20/812 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RBKS | USP32 | 0.802517 | 3 | 0 | 3 |
| RBKS | VDAC3 | 0.75357 | 3 | 0 | 3 |
| RBKS | TOM1L1 | 0.751587 | 3 | 0 | 3 |
| RBKS | PCSK5 | 0.74044 | 3 | 0 | 3 |
| RBKS | CETN3 | 0.738903 | 4 | 0 | 4 |
| RBKS | NCKAP1 | 0.73455 | 3 | 0 | 3 |
| RBKS | FOPNL | 0.725725 | 3 | 0 | 3 |
| RBKS | CCNYL1 | 0.722453 | 4 | 0 | 4 |
| RBKS | ADAM11 | 0.722422 | 3 | 0 | 3 |
| RBKS | KRT81 | 0.721496 | 3 | 0 | 3 |
| RBKS | STX3 | 0.720307 | 3 | 0 | 3 |
| RBKS | SLC30A4 | 0.718701 | 3 | 0 | 3 |
| RBKS | EPB41L5 | 0.716825 | 3 | 0 | 3 |
| RBKS | COPG2 | 0.716744 | 3 | 0 | 3 |
| RBKS | GYPC | 0.706865 | 3 | 0 | 3 |
| RBKS | WDR61 | 0.69894 | 4 | 0 | 3 |
| RBKS | EIF3J | 0.697494 | 3 | 0 | 3 |
| RBKS | KCNK6 | 0.696654 | 3 | 0 | 3 |
| RBKS | UBE2E2 | 0.691634 | 3 | 0 | 3 |
| RBKS | PDZD11 | 0.687417 | 3 | 0 | 3 |
For details and further investigation, click here
