| Full name: spermatogenesis associated 18 | Alias Symbol: FLJ32906 | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 132671 | HGNC ID: HGNC:29579 | Ensembl Gene: ENSG00000163071 | OMIM ID: 612814 |
| Drug and gene relationship at DGIdb | |||
Expression of SPATA18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATA18 | 132671 | 229331_at | -1.5845 | 0.0298 | |
| GSE26886 | SPATA18 | 132671 | 229331_at | -1.8434 | 0.0000 | |
| GSE45670 | SPATA18 | 132671 | 229331_at | -1.2443 | 0.0082 | |
| GSE53622 | SPATA18 | 132671 | 10958 | -1.5643 | 0.0000 | |
| GSE53624 | SPATA18 | 132671 | 10958 | -1.9603 | 0.0000 | |
| GSE63941 | SPATA18 | 132671 | 230723_at | 0.0414 | 0.8690 | |
| GSE77861 | SPATA18 | 132671 | 230723_at | -0.1376 | 0.2624 | |
| GSE97050 | SPATA18 | 132671 | A_23_P407112 | -0.1397 | 0.6479 | |
| SRP007169 | SPATA18 | 132671 | RNAseq | -1.9071 | 0.0008 | |
| SRP064894 | SPATA18 | 132671 | RNAseq | -0.8474 | 0.0002 | |
| SRP133303 | SPATA18 | 132671 | RNAseq | -1.2991 | 0.0000 | |
| SRP159526 | SPATA18 | 132671 | RNAseq | -1.9166 | 0.0000 | |
| SRP193095 | SPATA18 | 132671 | RNAseq | -1.5724 | 0.0000 | |
| SRP219564 | SPATA18 | 132671 | RNAseq | -1.5744 | 0.0001 | |
| TCGA | SPATA18 | 132671 | RNAseq | -0.5347 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by SPATA18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPATA18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATA18 | 132671 | 4 | 11 | 15 | |
| GSE20123 | SPATA18 | 132671 | 3 | 11 | 16 | |
| GSE43470 | SPATA18 | 132671 | 0 | 14 | 29 | |
| GSE46452 | SPATA18 | 132671 | 1 | 36 | 22 | |
| GSE47630 | SPATA18 | 132671 | 1 | 18 | 21 | |
| GSE54993 | SPATA18 | 132671 | 7 | 0 | 63 | |
| GSE54994 | SPATA18 | 132671 | 2 | 10 | 41 | |
| GSE60625 | SPATA18 | 132671 | 0 | 0 | 11 | |
| GSE74703 | SPATA18 | 132671 | 0 | 12 | 24 | |
| GSE74704 | SPATA18 | 132671 | 2 | 6 | 12 | |
| TCGA | SPATA18 | 132671 | 17 | 29 | 50 |
Total number of gains: 37; Total number of losses: 147; Total Number of normals: 304.
Somatic mutations of SPATA18:
Generating mutation plots.
Highly correlated genes for SPATA18:
Showing top 20/1506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATA18 | RRAGD | 0.792522 | 6 | 0 | 6 |
| SPATA18 | LIN7C | 0.769648 | 3 | 0 | 3 |
| SPATA18 | CPEB3 | 0.768742 | 6 | 0 | 6 |
| SPATA18 | FCER1A | 0.76617 | 6 | 0 | 6 |
| SPATA18 | ROR1 | 0.764221 | 5 | 0 | 5 |
| SPATA18 | NAGK | 0.762983 | 6 | 0 | 6 |
| SPATA18 | PSCA | 0.760328 | 3 | 0 | 3 |
| SPATA18 | FAM214A | 0.756314 | 5 | 0 | 5 |
| SPATA18 | KAT2B | 0.750591 | 7 | 0 | 6 |
| SPATA18 | MAL | 0.749438 | 5 | 0 | 5 |
| SPATA18 | CAPN5 | 0.748341 | 6 | 0 | 6 |
| SPATA18 | PADI1 | 0.747834 | 3 | 0 | 3 |
| SPATA18 | FBXO8 | 0.745504 | 6 | 0 | 6 |
| SPATA18 | TFAP2B | 0.745115 | 5 | 0 | 5 |
| SPATA18 | TMPRSS11B | 0.739781 | 5 | 0 | 5 |
| SPATA18 | C18orf25 | 0.736827 | 6 | 0 | 6 |
| SPATA18 | GOLGA4 | 0.735376 | 4 | 0 | 4 |
| SPATA18 | SCIN | 0.731805 | 6 | 0 | 6 |
| SPATA18 | CA13 | 0.73129 | 3 | 0 | 3 |
| SPATA18 | CDKN2AIP | 0.730578 | 6 | 0 | 6 |
For details and further investigation, click here
