| Full name: methyltransferase like 7B | Alias Symbol: MGC17301|ALDI | ||
| Type: protein-coding gene | Cytoband: 12q13.2 | ||
| Entrez ID: 196410 | HGNC ID: HGNC:28276 | Ensembl Gene: ENSG00000170439 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of METTL7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | METTL7B | 196410 | 227055_at | 0.3787 | 0.1416 | |
| GSE26886 | METTL7B | 196410 | 227055_at | 0.4403 | 0.0223 | |
| GSE45670 | METTL7B | 196410 | 227055_at | 0.2402 | 0.0700 | |
| GSE53622 | METTL7B | 196410 | 45164 | 0.8541 | 0.0000 | |
| GSE53624 | METTL7B | 196410 | 45164 | 0.6808 | 0.0000 | |
| GSE63941 | METTL7B | 196410 | 227055_at | 0.8296 | 0.3163 | |
| GSE77861 | METTL7B | 196410 | 227055_at | 0.1946 | 0.4021 | |
| GSE97050 | METTL7B | 196410 | A_24_P64653 | 0.6858 | 0.2666 | |
| SRP159526 | METTL7B | 196410 | RNAseq | 5.4720 | 0.0000 | |
| TCGA | METTL7B | 196410 | RNAseq | -0.1125 | 0.7703 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by METTL7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of METTL7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | METTL7B | 196410 | 4 | 1 | 25 | |
| GSE20123 | METTL7B | 196410 | 4 | 1 | 25 | |
| GSE43470 | METTL7B | 196410 | 4 | 0 | 39 | |
| GSE46452 | METTL7B | 196410 | 8 | 1 | 50 | |
| GSE47630 | METTL7B | 196410 | 10 | 2 | 28 | |
| GSE54993 | METTL7B | 196410 | 0 | 5 | 65 | |
| GSE54994 | METTL7B | 196410 | 4 | 1 | 48 | |
| GSE60625 | METTL7B | 196410 | 0 | 0 | 11 | |
| GSE74703 | METTL7B | 196410 | 4 | 0 | 32 | |
| GSE74704 | METTL7B | 196410 | 3 | 1 | 16 | |
| TCGA | METTL7B | 196410 | 15 | 10 | 71 |
Total number of gains: 56; Total number of losses: 22; Total Number of normals: 410.
Somatic mutations of METTL7B:
Generating mutation plots.
Highly correlated genes for METTL7B:
Showing top 20/135 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| METTL7B | FMNL1 | 0.774628 | 3 | 0 | 3 |
| METTL7B | HCK | 0.724493 | 3 | 0 | 3 |
| METTL7B | CPXM1 | 0.722488 | 4 | 0 | 4 |
| METTL7B | RENBP | 0.69489 | 4 | 0 | 3 |
| METTL7B | NGFR | 0.686378 | 4 | 0 | 3 |
| METTL7B | WAS | 0.679883 | 3 | 0 | 3 |
| METTL7B | HOXD8 | 0.675281 | 3 | 0 | 3 |
| METTL7B | FAM124B | 0.662309 | 3 | 0 | 3 |
| METTL7B | WNT1 | 0.652826 | 3 | 0 | 3 |
| METTL7B | BMF | 0.650412 | 5 | 0 | 4 |
| METTL7B | AIFM3 | 0.645974 | 3 | 0 | 3 |
| METTL7B | IER5L | 0.645496 | 3 | 0 | 3 |
| METTL7B | ABCD1 | 0.639325 | 3 | 0 | 3 |
| METTL7B | MANBA | 0.636175 | 3 | 0 | 3 |
| METTL7B | CD7 | 0.635245 | 3 | 0 | 3 |
| METTL7B | B3GAT3 | 0.63507 | 3 | 0 | 3 |
| METTL7B | PTGIR | 0.634995 | 3 | 0 | 3 |
| METTL7B | IGFLR1 | 0.633684 | 4 | 0 | 3 |
| METTL7B | LAIR2 | 0.632372 | 3 | 0 | 3 |
| METTL7B | PAM16 | 0.631851 | 3 | 0 | 3 |
For details and further investigation, click here
