| Full name: SR-related CTD associated factor 1 | Alias Symbol: SR-A1|FLJ00034 | ||
| Type: protein-coding gene | Cytoband: 19q13.3-q13.4 | ||
| Entrez ID: 58506 | HGNC ID: HGNC:30403 | Ensembl Gene: ENSG00000126461 | OMIM ID: 617264 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SCAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCAF1 | 58506 | 225500_x_at | 0.2271 | 0.5430 | |
| GSE26886 | SCAF1 | 58506 | 225500_x_at | 0.0994 | 0.3937 | |
| GSE45670 | SCAF1 | 58506 | 225500_x_at | 0.0469 | 0.5991 | |
| GSE53622 | SCAF1 | 58506 | 2278 | -0.1740 | 0.0016 | |
| GSE53624 | SCAF1 | 58506 | 2278 | 0.0638 | 0.2501 | |
| GSE63941 | SCAF1 | 58506 | 225500_x_at | 0.7507 | 0.0008 | |
| GSE77861 | SCAF1 | 58506 | 225500_x_at | 0.0268 | 0.8832 | |
| GSE97050 | SCAF1 | 58506 | A_24_P117672 | -0.0447 | 0.8689 | |
| SRP007169 | SCAF1 | 58506 | RNAseq | 0.3494 | 0.3711 | |
| SRP008496 | SCAF1 | 58506 | RNAseq | -0.2783 | 0.3970 | |
| SRP064894 | SCAF1 | 58506 | RNAseq | 0.4584 | 0.0401 | |
| SRP133303 | SCAF1 | 58506 | RNAseq | 0.3409 | 0.1492 | |
| SRP159526 | SCAF1 | 58506 | RNAseq | 0.5962 | 0.0058 | |
| SRP193095 | SCAF1 | 58506 | RNAseq | 0.4816 | 0.0016 | |
| SRP219564 | SCAF1 | 58506 | RNAseq | 0.0293 | 0.8793 | |
| TCGA | SCAF1 | 58506 | RNAseq | 0.0569 | 0.1778 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SCAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCAF1 | 58506 | 4 | 4 | 22 | |
| GSE20123 | SCAF1 | 58506 | 4 | 3 | 23 | |
| GSE43470 | SCAF1 | 58506 | 4 | 11 | 28 | |
| GSE46452 | SCAF1 | 58506 | 45 | 1 | 13 | |
| GSE47630 | SCAF1 | 58506 | 10 | 6 | 24 | |
| GSE54993 | SCAF1 | 58506 | 17 | 4 | 49 | |
| GSE54994 | SCAF1 | 58506 | 4 | 14 | 35 | |
| GSE60625 | SCAF1 | 58506 | 9 | 0 | 2 | |
| GSE74703 | SCAF1 | 58506 | 4 | 7 | 25 | |
| GSE74704 | SCAF1 | 58506 | 4 | 1 | 15 | |
| TCGA | SCAF1 | 58506 | 14 | 19 | 63 |
Total number of gains: 119; Total number of losses: 70; Total Number of normals: 299.
Somatic mutations of SCAF1:
Generating mutation plots.
Highly correlated genes for SCAF1:
Showing top 20/359 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCAF1 | RPRD2 | 0.841114 | 3 | 0 | 3 |
| SCAF1 | ZNF384 | 0.805338 | 3 | 0 | 3 |
| SCAF1 | FKBP4 | 0.795764 | 3 | 0 | 3 |
| SCAF1 | ZNF747 | 0.784285 | 3 | 0 | 3 |
| SCAF1 | CHD3 | 0.775318 | 3 | 0 | 3 |
| SCAF1 | ATAT1 | 0.770196 | 3 | 0 | 3 |
| SCAF1 | DDX11 | 0.769949 | 3 | 0 | 3 |
| SCAF1 | SUGP1 | 0.767545 | 4 | 0 | 4 |
| SCAF1 | KRI1 | 0.764481 | 3 | 0 | 3 |
| SCAF1 | SELPLG | 0.758862 | 3 | 0 | 3 |
| SCAF1 | NDUFA3 | 0.758595 | 3 | 0 | 3 |
| SCAF1 | SPEN | 0.755598 | 3 | 0 | 3 |
| SCAF1 | KDELR1 | 0.754612 | 3 | 0 | 3 |
| SCAF1 | AKT1 | 0.754001 | 3 | 0 | 3 |
| SCAF1 | MRPL38 | 0.750422 | 3 | 0 | 3 |
| SCAF1 | PRDM15 | 0.742638 | 3 | 0 | 3 |
| SCAF1 | NOP2 | 0.737449 | 3 | 0 | 3 |
| SCAF1 | MLF2 | 0.736826 | 3 | 0 | 3 |
| SCAF1 | GRWD1 | 0.733973 | 3 | 0 | 3 |
| SCAF1 | PDAP1 | 0.733786 | 3 | 0 | 3 |
For details and further investigation, click here
