| Full name: transmembrane protein 165 | Alias Symbol: TMPT27|TPARL|GDT1 | ||
| Type: protein-coding gene | Cytoband: 4q12 | ||
| Entrez ID: 55858 | HGNC ID: HGNC:30760 | Ensembl Gene: ENSG00000134851 | OMIM ID: 614726 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TMEM165:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM165 | 55858 | 226825_s_at | 0.3126 | 0.5383 | |
| GSE20347 | TMEM165 | 55858 | 218095_s_at | -0.4546 | 0.0005 | |
| GSE23400 | TMEM165 | 55858 | 218095_s_at | -0.2168 | 0.0224 | |
| GSE26886 | TMEM165 | 55858 | 218095_s_at | -0.2162 | 0.2563 | |
| GSE29001 | TMEM165 | 55858 | 218095_s_at | -0.1784 | 0.5954 | |
| GSE38129 | TMEM165 | 55858 | 218095_s_at | 0.0383 | 0.8638 | |
| GSE45670 | TMEM165 | 55858 | 226825_s_at | 0.0123 | 0.9650 | |
| GSE53622 | TMEM165 | 55858 | 87027 | -0.1870 | 0.0025 | |
| GSE53624 | TMEM165 | 55858 | 87027 | 0.0356 | 0.6809 | |
| GSE63941 | TMEM165 | 55858 | 226825_s_at | 0.2212 | 0.6283 | |
| GSE77861 | TMEM165 | 55858 | 226825_s_at | 0.1646 | 0.7694 | |
| GSE97050 | TMEM165 | 55858 | A_24_P43391 | -0.0693 | 0.7213 | |
| SRP007169 | TMEM165 | 55858 | RNAseq | -0.4999 | 0.1805 | |
| SRP008496 | TMEM165 | 55858 | RNAseq | -0.3192 | 0.1457 | |
| SRP064894 | TMEM165 | 55858 | RNAseq | 0.2694 | 0.1351 | |
| SRP133303 | TMEM165 | 55858 | RNAseq | 0.5420 | 0.0050 | |
| SRP159526 | TMEM165 | 55858 | RNAseq | -0.3091 | 0.2199 | |
| SRP193095 | TMEM165 | 55858 | RNAseq | -0.1008 | 0.4547 | |
| SRP219564 | TMEM165 | 55858 | RNAseq | -0.2352 | 0.2719 | |
| TCGA | TMEM165 | 55858 | RNAseq | 0.1041 | 0.0325 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM165 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM165:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM165 | 55858 | 3 | 11 | 16 | |
| GSE20123 | TMEM165 | 55858 | 2 | 11 | 17 | |
| GSE43470 | TMEM165 | 55858 | 0 | 14 | 29 | |
| GSE46452 | TMEM165 | 55858 | 1 | 36 | 22 | |
| GSE47630 | TMEM165 | 55858 | 1 | 18 | 21 | |
| GSE54993 | TMEM165 | 55858 | 7 | 0 | 63 | |
| GSE54994 | TMEM165 | 55858 | 2 | 10 | 41 | |
| GSE60625 | TMEM165 | 55858 | 0 | 0 | 11 | |
| GSE74703 | TMEM165 | 55858 | 0 | 12 | 24 | |
| GSE74704 | TMEM165 | 55858 | 1 | 6 | 13 | |
| TCGA | TMEM165 | 55858 | 20 | 27 | 49 |
Total number of gains: 37; Total number of losses: 145; Total Number of normals: 306.
Somatic mutations of TMEM165:
Generating mutation plots.
Highly correlated genes for TMEM165:
Showing top 20/351 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM165 | MBTPS1 | 0.732341 | 3 | 0 | 3 |
| TMEM165 | STT3B | 0.728637 | 3 | 0 | 3 |
| TMEM165 | SLFN12 | 0.721114 | 3 | 0 | 3 |
| TMEM165 | PSMD8 | 0.719234 | 3 | 0 | 3 |
| TMEM165 | CD38 | 0.717748 | 3 | 0 | 3 |
| TMEM165 | PSMB7 | 0.710221 | 3 | 0 | 3 |
| TMEM165 | UBR5 | 0.709664 | 3 | 0 | 3 |
| TMEM165 | CTDSPL2 | 0.707864 | 3 | 0 | 3 |
| TMEM165 | MFN1 | 0.707621 | 4 | 0 | 4 |
| TMEM165 | CSTF2 | 0.706812 | 3 | 0 | 3 |
| TMEM165 | MBNL3 | 0.703532 | 4 | 0 | 4 |
| TMEM165 | FMO4 | 0.694823 | 3 | 0 | 3 |
| TMEM165 | CCDC127 | 0.690068 | 3 | 0 | 3 |
| TMEM165 | HDAC3 | 0.690061 | 4 | 0 | 3 |
| TMEM165 | ECD | 0.688114 | 3 | 0 | 3 |
| TMEM165 | POLI | 0.68706 | 3 | 0 | 3 |
| TMEM165 | QSER1 | 0.686787 | 4 | 0 | 3 |
| TMEM165 | MAPK6 | 0.683864 | 5 | 0 | 5 |
| TMEM165 | ARMC10 | 0.682516 | 3 | 0 | 3 |
| TMEM165 | C2orf68 | 0.681874 | 4 | 0 | 3 |
For details and further investigation, click here
