| Full name: catenin alpha 3 | Alias Symbol: VR22|MGC26194 | ||
| Type: protein-coding gene | Cytoband: 10q21.3 | ||
| Entrez ID: 29119 | HGNC ID: HGNC:2511 | Ensembl Gene: ENSG00000183230 | OMIM ID: 607667 |
| Drug and gene relationship at DGIdb | |||
CTNNA3 involved pathways:
Expression of CTNNA3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CTNNA3 | 29119 | 241255_at | -0.6119 | 0.5943 | |
| GSE20347 | CTNNA3 | 29119 | 220815_at | 0.0438 | 0.6685 | |
| GSE23400 | CTNNA3 | 29119 | 220815_at | -0.0404 | 0.3287 | |
| GSE26886 | CTNNA3 | 29119 | 220815_at | -0.0599 | 0.6604 | |
| GSE29001 | CTNNA3 | 29119 | 220815_at | -0.1298 | 0.2769 | |
| GSE38129 | CTNNA3 | 29119 | 220815_at | -0.2343 | 0.0483 | |
| GSE45670 | CTNNA3 | 29119 | 236576_at | -0.9041 | 0.0014 | |
| GSE53622 | CTNNA3 | 29119 | 46780 | -2.4997 | 0.0000 | |
| GSE53624 | CTNNA3 | 29119 | 46780 | -1.6393 | 0.0000 | |
| GSE63941 | CTNNA3 | 29119 | 220815_at | 0.2695 | 0.0227 | |
| GSE77861 | CTNNA3 | 29119 | 220815_at | -0.0691 | 0.6251 | |
| GSE97050 | CTNNA3 | 29119 | A_33_P3302191 | -1.2342 | 0.1163 | |
| SRP133303 | CTNNA3 | 29119 | RNAseq | -2.7466 | 0.0000 | |
| SRP159526 | CTNNA3 | 29119 | RNAseq | -0.3748 | 0.6458 | |
| TCGA | CTNNA3 | 29119 | RNAseq | -1.5285 | 0.0846 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CTNNA3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CTNNA3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CTNNA3 | 29119 | 2 | 8 | 20 | |
| GSE20123 | CTNNA3 | 29119 | 2 | 8 | 20 | |
| GSE43470 | CTNNA3 | 29119 | 1 | 8 | 34 | |
| GSE46452 | CTNNA3 | 29119 | 0 | 11 | 48 | |
| GSE47630 | CTNNA3 | 29119 | 3 | 14 | 23 | |
| GSE54993 | CTNNA3 | 29119 | 8 | 0 | 62 | |
| GSE54994 | CTNNA3 | 29119 | 3 | 11 | 39 | |
| GSE60625 | CTNNA3 | 29119 | 0 | 0 | 11 | |
| GSE74703 | CTNNA3 | 29119 | 1 | 5 | 30 | |
| GSE74704 | CTNNA3 | 29119 | 1 | 6 | 13 | |
| TCGA | CTNNA3 | 29119 | 11 | 23 | 62 |
Total number of gains: 32; Total number of losses: 94; Total Number of normals: 362.
Somatic mutations of CTNNA3:
Generating mutation plots.
Highly correlated genes for CTNNA3:
Showing top 20/650 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CTNNA3 | IQUB | 0.842839 | 3 | 0 | 3 |
| CTNNA3 | RBPMS2 | 0.822383 | 5 | 0 | 5 |
| CTNNA3 | MYOM1 | 0.815457 | 5 | 0 | 5 |
| CTNNA3 | ANO5 | 0.810766 | 5 | 0 | 5 |
| CTNNA3 | SYNC | 0.808328 | 3 | 0 | 3 |
| CTNNA3 | FNDC5 | 0.797892 | 4 | 0 | 4 |
| CTNNA3 | NACC2 | 0.796188 | 5 | 0 | 5 |
| CTNNA3 | HSPB7 | 0.791426 | 6 | 0 | 5 |
| CTNNA3 | C9orf47 | 0.786828 | 3 | 0 | 3 |
| CTNNA3 | PDZRN4 | 0.78602 | 5 | 0 | 5 |
| CTNNA3 | FLNC | 0.777113 | 6 | 0 | 6 |
| CTNNA3 | CADM2 | 0.776823 | 5 | 0 | 5 |
| CTNNA3 | XKR4 | 0.775538 | 5 | 0 | 5 |
| CTNNA3 | PLN | 0.770722 | 5 | 0 | 5 |
| CTNNA3 | KCNMB1 | 0.770093 | 6 | 0 | 6 |
| CTNNA3 | SLMAP | 0.769258 | 5 | 0 | 5 |
| CTNNA3 | UBXN10 | 0.767872 | 4 | 0 | 3 |
| CTNNA3 | PPP1R14A | 0.767442 | 5 | 0 | 5 |
| CTNNA3 | PRR26 | 0.765678 | 4 | 0 | 4 |
| CTNNA3 | RAB9B | 0.761571 | 5 | 0 | 5 |
For details and further investigation, click here
