| Full name: core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | Alias Symbol: C1GALT|T-synthase | ||
| Type: protein-coding gene | Cytoband: 7p22.1-p21.3 | ||
| Entrez ID: 56913 | HGNC ID: HGNC:24337 | Ensembl Gene: ENSG00000106392 | OMIM ID: 610555 |
Screen Evidence:
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Expression of C1GALT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C1GALT1 | 56913 | 219439_at | -0.7700 | 0.3827 | |
| GSE20347 | C1GALT1 | 56913 | 219439_at | -1.2001 | 0.0000 | |
| GSE23400 | C1GALT1 | 56913 | 219439_at | -0.4235 | 0.0000 | |
| GSE26886 | C1GALT1 | 56913 | 219439_at | -1.1255 | 0.0001 | |
| GSE29001 | C1GALT1 | 56913 | 219439_at | -0.9220 | 0.0427 | |
| GSE38129 | C1GALT1 | 56913 | 219439_at | -0.6651 | 0.0059 | |
| GSE45670 | C1GALT1 | 56913 | 219439_at | -0.2236 | 0.3763 | |
| GSE53622 | C1GALT1 | 56913 | 18677 | -0.6745 | 0.0000 | |
| GSE53624 | C1GALT1 | 56913 | 18677 | -1.0170 | 0.0000 | |
| GSE63941 | C1GALT1 | 56913 | 219439_at | 0.2288 | 0.7602 | |
| GSE77861 | C1GALT1 | 56913 | 219439_at | -1.1157 | 0.0073 | |
| GSE97050 | C1GALT1 | 56913 | A_23_P252145 | 0.1234 | 0.8589 | |
| SRP007169 | C1GALT1 | 56913 | RNAseq | -1.3047 | 0.0001 | |
| SRP008496 | C1GALT1 | 56913 | RNAseq | -1.0393 | 0.0000 | |
| SRP064894 | C1GALT1 | 56913 | RNAseq | -1.0417 | 0.0000 | |
| SRP133303 | C1GALT1 | 56913 | RNAseq | -0.4193 | 0.0421 | |
| SRP159526 | C1GALT1 | 56913 | RNAseq | -0.8940 | 0.0564 | |
| SRP193095 | C1GALT1 | 56913 | RNAseq | -1.1341 | 0.0000 | |
| SRP219564 | C1GALT1 | 56913 | RNAseq | -0.6219 | 0.2735 | |
| TCGA | C1GALT1 | 56913 | RNAseq | -0.0977 | 0.2908 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by C1GALT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C1GALT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C1GALT1 | 56913 | 15 | 1 | 14 | |
| GSE20123 | C1GALT1 | 56913 | 15 | 1 | 14 | |
| GSE43470 | C1GALT1 | 56913 | 8 | 0 | 35 | |
| GSE46452 | C1GALT1 | 56913 | 11 | 1 | 47 | |
| GSE47630 | C1GALT1 | 56913 | 9 | 1 | 30 | |
| GSE54993 | C1GALT1 | 56913 | 0 | 6 | 64 | |
| GSE54994 | C1GALT1 | 56913 | 21 | 1 | 31 | |
| GSE60625 | C1GALT1 | 56913 | 0 | 0 | 11 | |
| GSE74703 | C1GALT1 | 56913 | 8 | 0 | 28 | |
| GSE74704 | C1GALT1 | 56913 | 9 | 0 | 11 | |
| TCGA | C1GALT1 | 56913 | 56 | 4 | 36 |
Total number of gains: 152; Total number of losses: 15; Total Number of normals: 321.
Somatic mutations of C1GALT1:
Generating mutation plots.
Highly correlated genes for C1GALT1:
Showing top 20/1248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C1GALT1 | GALE | 0.739927 | 11 | 0 | 10 |
| C1GALT1 | UBE2E2 | 0.732646 | 3 | 0 | 3 |
| C1GALT1 | TMOD3 | 0.729962 | 12 | 0 | 11 |
| C1GALT1 | CWH43 | 0.728571 | 10 | 0 | 10 |
| C1GALT1 | FRMD4B | 0.728094 | 11 | 0 | 11 |
| C1GALT1 | PTK6 | 0.721062 | 10 | 0 | 10 |
| C1GALT1 | WWC1 | 0.712594 | 11 | 0 | 11 |
| C1GALT1 | ALS2CL | 0.712237 | 10 | 0 | 10 |
| C1GALT1 | SH3GL1 | 0.710899 | 10 | 0 | 10 |
| C1GALT1 | TP53I3 | 0.710636 | 11 | 0 | 11 |
| C1GALT1 | ZDHHC12 | 0.710228 | 3 | 0 | 3 |
| C1GALT1 | PDCD6IP | 0.709939 | 11 | 0 | 10 |
| C1GALT1 | KRT78 | 0.709809 | 6 | 0 | 6 |
| C1GALT1 | C6orf132 | 0.699383 | 6 | 0 | 6 |
| C1GALT1 | DHRS1 | 0.698183 | 10 | 0 | 9 |
| C1GALT1 | ABHD5 | 0.697265 | 11 | 0 | 11 |
| C1GALT1 | EPS8L2 | 0.696039 | 10 | 0 | 10 |
| C1GALT1 | SESN2 | 0.692872 | 7 | 0 | 7 |
| C1GALT1 | GRPEL2 | 0.692629 | 7 | 0 | 7 |
| C1GALT1 | ZNRF1 | 0.69258 | 4 | 0 | 3 |
For details and further investigation, click here
