| Full name: ER membrane protein complex subunit 8 | Alias Symbol: FAM158B | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 10328 | HGNC ID: HGNC:7864 | Ensembl Gene: ENSG00000131148 | OMIM ID: 604886 |
Expression of EMC8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMC8 | 10328 | 227363_s_at | 0.7081 | 0.0685 | |
| GSE20347 | EMC8 | 10328 | 218057_x_at | 0.5699 | 0.0008 | |
| GSE23400 | EMC8 | 10328 | 218057_x_at | 0.4774 | 0.0000 | |
| GSE26886 | EMC8 | 10328 | 227363_s_at | 0.8934 | 0.0000 | |
| GSE29001 | EMC8 | 10328 | 218057_x_at | 0.5209 | 0.0386 | |
| GSE38129 | EMC8 | 10328 | 218057_x_at | 0.7702 | 0.0000 | |
| GSE45670 | EMC8 | 10328 | 227363_s_at | 0.4108 | 0.0113 | |
| GSE53622 | EMC8 | 10328 | 163417 | 0.4108 | 0.0000 | |
| GSE53624 | EMC8 | 10328 | 163417 | 0.7364 | 0.0000 | |
| GSE63941 | EMC8 | 10328 | 227363_s_at | 0.5862 | 0.1241 | |
| GSE77861 | EMC8 | 10328 | 227363_s_at | 0.6091 | 0.0079 | |
| SRP007169 | EMC8 | 10328 | RNAseq | 0.3734 | 0.2828 | |
| SRP008496 | EMC8 | 10328 | RNAseq | 0.4183 | 0.0914 | |
| SRP064894 | EMC8 | 10328 | RNAseq | 0.4220 | 0.0228 | |
| SRP133303 | EMC8 | 10328 | RNAseq | 0.8163 | 0.0000 | |
| SRP159526 | EMC8 | 10328 | RNAseq | 0.7153 | 0.0332 | |
| SRP193095 | EMC8 | 10328 | RNAseq | 0.4864 | 0.0001 | |
| SRP219564 | EMC8 | 10328 | RNAseq | 0.2811 | 0.4646 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EMC8 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of EMC8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMC8 | 10328 | 4 | 4 | 22 | |
| GSE20123 | EMC8 | 10328 | 4 | 4 | 22 | |
| GSE43470 | EMC8 | 10328 | 2 | 10 | 31 | |
| GSE46452 | EMC8 | 10328 | 37 | 2 | 20 | |
| GSE47630 | EMC8 | 10328 | 11 | 9 | 20 | |
| GSE54993 | EMC8 | 10328 | 3 | 4 | 63 | |
| GSE54994 | EMC8 | 10328 | 9 | 10 | 34 | |
| GSE60625 | EMC8 | 10328 | 4 | 0 | 7 | |
| GSE74703 | EMC8 | 10328 | 1 | 7 | 28 | |
| GSE74704 | EMC8 | 10328 | 3 | 2 | 15 | |
| TCGA | EMC8 | 10328 | 26 | 16 | 54 |
Total number of gains: 104; Total number of losses: 68; Total Number of normals: 316.
Somatic mutations of EMC8:
Generating mutation plots.
Highly correlated genes for EMC8:
Showing top 20/1515 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMC8 | CMC2 | 0.756879 | 11 | 0 | 11 |
| EMC8 | NUP93 | 0.75099 | 10 | 0 | 9 |
| EMC8 | GINS2 | 0.7408 | 11 | 0 | 11 |
| EMC8 | CDT1 | 0.738091 | 11 | 0 | 11 |
| EMC8 | CENPN | 0.733464 | 11 | 0 | 11 |
| EMC8 | USP10 | 0.727312 | 10 | 0 | 10 |
| EMC8 | SDCCAG8 | 0.724554 | 3 | 0 | 3 |
| EMC8 | DCTPP1 | 0.721023 | 11 | 0 | 11 |
| EMC8 | DDX28 | 0.718898 | 9 | 0 | 8 |
| EMC8 | BIRC5 | 0.71095 | 9 | 0 | 8 |
| EMC8 | CTU2 | 0.709816 | 6 | 0 | 5 |
| EMC8 | PGP | 0.708713 | 5 | 0 | 5 |
| EMC8 | CCDC86 | 0.704359 | 7 | 0 | 6 |
| EMC8 | LRRC59 | 0.703474 | 7 | 0 | 7 |
| EMC8 | CDC6 | 0.699671 | 9 | 0 | 8 |
| EMC8 | PUS7 | 0.697573 | 9 | 0 | 9 |
| EMC8 | PNPT1 | 0.697485 | 5 | 0 | 5 |
| EMC8 | IMP4 | 0.695544 | 11 | 0 | 11 |
| EMC8 | DTYMK | 0.693096 | 11 | 0 | 10 |
| EMC8 | RUVBL1 | 0.692861 | 11 | 0 | 10 |
For details and further investigation, click here
