| Full name: adaptor related protein complex 5 subunit sigma 1 | Alias Symbol: FLJ11168 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 55317 | HGNC ID: HGNC:15875 | Ensembl Gene: ENSG00000125843 | OMIM ID: 614824 |
Expression of AP5S1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AP5S1 | 55317 | 219706_at | 0.2437 | 0.4482 | |
| GSE20347 | AP5S1 | 55317 | 219706_at | 0.3113 | 0.0069 | |
| GSE23400 | AP5S1 | 55317 | 219706_at | 0.1578 | 0.0005 | |
| GSE26886 | AP5S1 | 55317 | 219706_at | 0.7769 | 0.0002 | |
| GSE29001 | AP5S1 | 55317 | 219706_at | 0.2415 | 0.2611 | |
| GSE38129 | AP5S1 | 55317 | 219706_at | 0.3874 | 0.0014 | |
| GSE45670 | AP5S1 | 55317 | 219706_at | 0.5013 | 0.0043 | |
| GSE53622 | AP5S1 | 55317 | 43684 | 0.3252 | 0.0040 | |
| GSE53624 | AP5S1 | 55317 | 43684 | 0.7849 | 0.0000 | |
| GSE63941 | AP5S1 | 55317 | 219706_at | -1.1355 | 0.0124 | |
| GSE77861 | AP5S1 | 55317 | 219706_at | 0.1424 | 0.4101 | |
| SRP007169 | AP5S1 | 55317 | RNAseq | -0.6881 | 0.0860 | |
| SRP008496 | AP5S1 | 55317 | RNAseq | -0.4853 | 0.1800 | |
| SRP064894 | AP5S1 | 55317 | RNAseq | 0.9301 | 0.0002 | |
| SRP133303 | AP5S1 | 55317 | RNAseq | 0.1511 | 0.2152 | |
| SRP159526 | AP5S1 | 55317 | RNAseq | 0.5231 | 0.0659 | |
| SRP193095 | AP5S1 | 55317 | RNAseq | 0.1364 | 0.1702 | |
| SRP219564 | AP5S1 | 55317 | RNAseq | 0.5373 | 0.0333 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AP5S1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of AP5S1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AP5S1 | 55317 | 12 | 3 | 15 | |
| GSE20123 | AP5S1 | 55317 | 13 | 3 | 14 | |
| GSE43470 | AP5S1 | 55317 | 10 | 1 | 32 | |
| GSE46452 | AP5S1 | 55317 | 26 | 1 | 32 | |
| GSE47630 | AP5S1 | 55317 | 18 | 4 | 18 | |
| GSE54993 | AP5S1 | 55317 | 2 | 14 | 54 | |
| GSE54994 | AP5S1 | 55317 | 22 | 3 | 28 | |
| GSE60625 | AP5S1 | 55317 | 0 | 0 | 11 | |
| GSE74703 | AP5S1 | 55317 | 9 | 1 | 26 | |
| GSE74704 | AP5S1 | 55317 | 8 | 1 | 11 | |
| TCGA | AP5S1 | 55317 | 39 | 11 | 46 |
Total number of gains: 159; Total number of losses: 42; Total Number of normals: 287.
Somatic mutations of AP5S1:
Generating mutation plots.
Highly correlated genes for AP5S1:
Showing top 20/277 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AP5S1 | DOCK4 | 0.744679 | 3 | 0 | 3 |
| AP5S1 | RRBP1 | 0.69498 | 6 | 0 | 5 |
| AP5S1 | PTP4A2 | 0.681618 | 3 | 0 | 3 |
| AP5S1 | LTBP2 | 0.674405 | 3 | 0 | 3 |
| AP5S1 | STMN3 | 0.670569 | 3 | 0 | 3 |
| AP5S1 | SMIM3 | 0.667301 | 3 | 0 | 3 |
| AP5S1 | ABL1 | 0.665876 | 3 | 0 | 3 |
| AP5S1 | EVA1B | 0.662823 | 3 | 0 | 3 |
| AP5S1 | GPX8 | 0.655789 | 4 | 0 | 3 |
| AP5S1 | FAP | 0.653487 | 4 | 0 | 3 |
| AP5S1 | LRRC17 | 0.645105 | 4 | 0 | 4 |
| AP5S1 | PDGFRB | 0.639261 | 4 | 0 | 3 |
| AP5S1 | CLEC11A | 0.637573 | 5 | 0 | 4 |
| AP5S1 | PET117 | 0.634442 | 4 | 0 | 3 |
| AP5S1 | A1BG | 0.633879 | 3 | 0 | 3 |
| AP5S1 | EARS2 | 0.633409 | 3 | 0 | 3 |
| AP5S1 | HEXB | 0.633278 | 5 | 0 | 4 |
| AP5S1 | FOXL1 | 0.631813 | 4 | 0 | 4 |
| AP5S1 | CSGALNACT2 | 0.630956 | 4 | 0 | 3 |
| AP5S1 | CCM2 | 0.62884 | 5 | 0 | 4 |
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