| Full name: formyl peptide receptor 2 | Alias Symbol: LXA4R|HM63|FPRH2|FMLPX|FPR2A|FMLP-R-II|ALXR | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 2358 | HGNC ID: HGNC:3827 | Ensembl Gene: ENSG00000171049 | OMIM ID: 136538 |
| Drug and gene relationship at DGIdb | |||
FPR2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05150 | Staphylococcus aureus infection |
Expression of FPR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FPR2 | 2358 | 210773_s_at | 0.9458 | 0.3119 | |
| GSE20347 | FPR2 | 2358 | 210773_s_at | 0.0577 | 0.4404 | |
| GSE23400 | FPR2 | 2358 | 210773_s_at | -0.0194 | 0.6277 | |
| GSE26886 | FPR2 | 2358 | 210773_s_at | 0.0986 | 0.4558 | |
| GSE29001 | FPR2 | 2358 | 210773_s_at | -0.0240 | 0.9104 | |
| GSE38129 | FPR2 | 2358 | 210773_s_at | 0.0136 | 0.8576 | |
| GSE45670 | FPR2 | 2358 | 210773_s_at | 0.0461 | 0.7408 | |
| GSE63941 | FPR2 | 2358 | 210773_s_at | 0.2818 | 0.1331 | |
| GSE77861 | FPR2 | 2358 | 210772_at | -0.0311 | 0.7843 | |
| SRP007169 | FPR2 | 2358 | RNAseq | 4.9917 | 0.0005 | |
| SRP133303 | FPR2 | 2358 | RNAseq | 2.8366 | 0.0000 | |
| TCGA | FPR2 | 2358 | RNAseq | 0.4376 | 0.2381 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by FPR2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of FPR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FPR2 | 2358 | 3 | 4 | 23 | |
| GSE20123 | FPR2 | 2358 | 3 | 3 | 24 | |
| GSE43470 | FPR2 | 2358 | 3 | 12 | 28 | |
| GSE46452 | FPR2 | 2358 | 45 | 1 | 13 | |
| GSE47630 | FPR2 | 2358 | 10 | 6 | 24 | |
| GSE54993 | FPR2 | 2358 | 17 | 4 | 49 | |
| GSE54994 | FPR2 | 2358 | 4 | 14 | 35 | |
| GSE60625 | FPR2 | 2358 | 9 | 0 | 2 | |
| GSE74703 | FPR2 | 2358 | 3 | 8 | 25 | |
| GSE74704 | FPR2 | 2358 | 3 | 1 | 16 | |
| TCGA | FPR2 | 2358 | 14 | 20 | 62 |
Total number of gains: 114; Total number of losses: 73; Total Number of normals: 301.
Somatic mutations of FPR2:
Generating mutation plots.
Highly correlated genes for FPR2:
Showing top 20/357 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FPR2 | FCGR2C | 0.728015 | 3 | 0 | 3 |
| FPR2 | OBSL1 | 0.716115 | 3 | 0 | 3 |
| FPR2 | BRS3 | 0.703596 | 3 | 0 | 3 |
| FPR2 | SYT13 | 0.693237 | 3 | 0 | 3 |
| FPR2 | ZPBP | 0.664553 | 4 | 0 | 4 |
| FPR2 | CDH4 | 0.661389 | 3 | 0 | 3 |
| FPR2 | LINC01361 | 0.659408 | 3 | 0 | 3 |
| FPR2 | ADAMTS12 | 0.658586 | 5 | 0 | 4 |
| FPR2 | TTR | 0.656629 | 3 | 0 | 3 |
| FPR2 | CYP7A1 | 0.652673 | 3 | 0 | 3 |
| FPR2 | LGALS14 | 0.649064 | 3 | 0 | 3 |
| FPR2 | SLC9A5 | 0.645979 | 4 | 0 | 3 |
| FPR2 | MAGEA8 | 0.644674 | 3 | 0 | 3 |
| FPR2 | IFNA17 | 0.642434 | 3 | 0 | 3 |
| FPR2 | FOXN3-AS2 | 0.642358 | 5 | 0 | 5 |
| FPR2 | RUNDC3A | 0.640525 | 4 | 0 | 3 |
| FPR2 | CPA2 | 0.639765 | 4 | 0 | 3 |
| FPR2 | CDC25C | 0.638223 | 4 | 0 | 4 |
| FPR2 | FOXD2 | 0.636476 | 3 | 0 | 3 |
| FPR2 | IFNA10 | 0.63379 | 3 | 0 | 3 |
For details and further investigation, click here
