| Full name: zona pellucida binding protein | Alias Symbol: SP38|ZPBP1 | ||
| Type: protein-coding gene | Cytoband: 7p12.2 | ||
| Entrez ID: 11055 | HGNC ID: HGNC:15662 | Ensembl Gene: ENSG00000042813 | OMIM ID: 608498 |
| Drug and gene relationship at DGIdb | |||
Expression of ZPBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZPBP | 11055 | 207021_at | -0.1366 | 0.4954 | |
| GSE20347 | ZPBP | 11055 | 207021_at | 0.1390 | 0.0446 | |
| GSE23400 | ZPBP | 11055 | 207021_at | -0.0522 | 0.1233 | |
| GSE26886 | ZPBP | 11055 | 207021_at | -0.1403 | 0.0948 | |
| GSE29001 | ZPBP | 11055 | 207021_at | 0.0572 | 0.7773 | |
| GSE38129 | ZPBP | 11055 | 207021_at | 0.0239 | 0.7070 | |
| GSE45670 | ZPBP | 11055 | 207021_at | 0.1658 | 0.1513 | |
| GSE53622 | ZPBP | 11055 | 73951 | -0.0176 | 0.9128 | |
| GSE53624 | ZPBP | 11055 | 73951 | 0.0319 | 0.7710 | |
| GSE63941 | ZPBP | 11055 | 207021_at | -0.0825 | 0.6223 | |
| GSE77861 | ZPBP | 11055 | 207021_at | -0.0412 | 0.7183 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZPBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZPBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZPBP | 11055 | 12 | 0 | 18 | |
| GSE20123 | ZPBP | 11055 | 11 | 0 | 19 | |
| GSE43470 | ZPBP | 11055 | 4 | 1 | 38 | |
| GSE46452 | ZPBP | 11055 | 11 | 1 | 47 | |
| GSE47630 | ZPBP | 11055 | 8 | 1 | 31 | |
| GSE54993 | ZPBP | 11055 | 0 | 8 | 62 | |
| GSE54994 | ZPBP | 11055 | 18 | 2 | 33 | |
| GSE60625 | ZPBP | 11055 | 0 | 0 | 11 | |
| GSE74703 | ZPBP | 11055 | 4 | 1 | 31 | |
| GSE74704 | ZPBP | 11055 | 5 | 0 | 15 | |
| TCGA | ZPBP | 11055 | 48 | 10 | 38 |
Total number of gains: 121; Total number of losses: 24; Total Number of normals: 343.
Somatic mutations of ZPBP:
Generating mutation plots.
Highly correlated genes for ZPBP:
Showing top 20/315 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZPBP | CAPN11 | 0.706688 | 3 | 0 | 3 |
| ZPBP | CDH22 | 0.700132 | 3 | 0 | 3 |
| ZPBP | ADARB2-AS1 | 0.695846 | 3 | 0 | 3 |
| ZPBP | TBXA2R | 0.670113 | 3 | 0 | 3 |
| ZPBP | IFNA7 | 0.667 | 5 | 0 | 5 |
| ZPBP | FPR2 | 0.664553 | 4 | 0 | 4 |
| ZPBP | CDHR2 | 0.663784 | 3 | 0 | 3 |
| ZPBP | OBSL1 | 0.663522 | 3 | 0 | 3 |
| ZPBP | GABRG2 | 0.662321 | 4 | 0 | 4 |
| ZPBP | NCR3 | 0.658457 | 3 | 0 | 3 |
| ZPBP | FGL1 | 0.657327 | 3 | 0 | 3 |
| ZPBP | FBXL18 | 0.657025 | 3 | 0 | 3 |
| ZPBP | PIWIL2 | 0.655005 | 3 | 0 | 3 |
| ZPBP | SCGB1D1 | 0.654945 | 3 | 0 | 3 |
| ZPBP | CRYGC | 0.653658 | 3 | 0 | 3 |
| ZPBP | SSUH2 | 0.648423 | 4 | 0 | 4 |
| ZPBP | C1orf68 | 0.643722 | 3 | 0 | 3 |
| ZPBP | RPGRIP1 | 0.643642 | 4 | 0 | 3 |
| ZPBP | MAP1LC3C | 0.643465 | 3 | 0 | 3 |
| ZPBP | FBXO40 | 0.641495 | 4 | 0 | 4 |
For details and further investigation, click here
