| Full name: solute carrier family 9 member A5 | Alias Symbol: NHE5 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 6553 | HGNC ID: HGNC:11078 | Ensembl Gene: ENSG00000135740 | OMIM ID: 600477 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC9A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC9A5 | 6553 | 220650_s_at | 0.1045 | 0.7944 | |
| GSE20347 | SLC9A5 | 6553 | 220650_s_at | 0.1514 | 0.1011 | |
| GSE23400 | SLC9A5 | 6553 | 220650_s_at | -0.0295 | 0.4578 | |
| GSE26886 | SLC9A5 | 6553 | 1559092_at | -0.1028 | 0.2117 | |
| GSE29001 | SLC9A5 | 6553 | 220650_s_at | 0.0825 | 0.6385 | |
| GSE38129 | SLC9A5 | 6553 | 220650_s_at | 0.0559 | 0.5414 | |
| GSE45670 | SLC9A5 | 6553 | 220650_s_at | 0.1351 | 0.2207 | |
| GSE53622 | SLC9A5 | 6553 | 50666 | 0.2228 | 0.0000 | |
| GSE53624 | SLC9A5 | 6553 | 79269 | 0.4017 | 0.0000 | |
| GSE63941 | SLC9A5 | 6553 | 220650_s_at | -0.2265 | 0.2210 | |
| GSE77861 | SLC9A5 | 6553 | 1559092_at | -0.0203 | 0.8998 | |
| GSE97050 | SLC9A5 | 6553 | A_23_P129433 | 0.0746 | 0.8020 | |
| SRP064894 | SLC9A5 | 6553 | RNAseq | 1.8057 | 0.0000 | |
| SRP133303 | SLC9A5 | 6553 | RNAseq | 0.2570 | 0.3152 | |
| SRP193095 | SLC9A5 | 6553 | RNAseq | 1.1429 | 0.0000 | |
| SRP219564 | SLC9A5 | 6553 | RNAseq | 0.8061 | 0.0113 | |
| TCGA | SLC9A5 | 6553 | RNAseq | 0.4223 | 0.0340 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SLC9A5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC9A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC9A5 | 6553 | 9 | 2 | 19 | |
| GSE20123 | SLC9A5 | 6553 | 9 | 2 | 19 | |
| GSE43470 | SLC9A5 | 6553 | 1 | 9 | 33 | |
| GSE46452 | SLC9A5 | 6553 | 38 | 1 | 20 | |
| GSE47630 | SLC9A5 | 6553 | 10 | 8 | 22 | |
| GSE54993 | SLC9A5 | 6553 | 2 | 4 | 64 | |
| GSE54994 | SLC9A5 | 6553 | 8 | 10 | 35 | |
| GSE60625 | SLC9A5 | 6553 | 4 | 0 | 7 | |
| GSE74703 | SLC9A5 | 6553 | 1 | 6 | 29 | |
| GSE74704 | SLC9A5 | 6553 | 5 | 1 | 14 | |
| TCGA | SLC9A5 | 6553 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 55; Total Number of normals: 317.
Somatic mutations of SLC9A5:
Generating mutation plots.
Highly correlated genes for SLC9A5:
Showing top 20/446 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC9A5 | KSR1 | 0.75977 | 3 | 0 | 3 |
| SLC9A5 | NPY2R | 0.72044 | 3 | 0 | 3 |
| SLC9A5 | ADTRP | 0.691779 | 3 | 0 | 3 |
| SLC9A5 | SLC6A18 | 0.688614 | 3 | 0 | 3 |
| SLC9A5 | NOS2 | 0.678885 | 3 | 0 | 3 |
| SLC9A5 | NCR3 | 0.674089 | 5 | 0 | 4 |
| SLC9A5 | VPREB3 | 0.668613 | 3 | 0 | 3 |
| SLC9A5 | IL9R | 0.667135 | 5 | 0 | 4 |
| SLC9A5 | CHSY3 | 0.66511 | 3 | 0 | 3 |
| SLC9A5 | CACNA1I | 0.662277 | 5 | 0 | 5 |
| SLC9A5 | GNRHR | 0.660625 | 4 | 0 | 3 |
| SLC9A5 | GPR88 | 0.654638 | 4 | 0 | 4 |
| SLC9A5 | GFI1B | 0.654365 | 3 | 0 | 3 |
| SLC9A5 | PSMB11 | 0.654238 | 3 | 0 | 3 |
| SLC9A5 | LIM2 | 0.654165 | 4 | 0 | 3 |
| SLC9A5 | CSGALNACT2 | 0.653106 | 3 | 0 | 3 |
| SLC9A5 | AGRP | 0.651099 | 5 | 0 | 4 |
| SLC9A5 | SNAP25 | 0.650103 | 4 | 0 | 4 |
| SLC9A5 | CDRT15 | 0.648338 | 4 | 0 | 3 |
| SLC9A5 | FPR2 | 0.645979 | 4 | 0 | 3 |
For details and further investigation, click here
