| Full name: forkhead box D2 | Alias Symbol: FREAC9 | ||
| Type: protein-coding gene | Cytoband: 1p33 | ||
| Entrez ID: 2306 | HGNC ID: HGNC:3803 | Ensembl Gene: ENSG00000186564 | OMIM ID: 602211 |
| Drug and gene relationship at DGIdb | |||
Expression of FOXD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FOXD2 | 2306 | 207653_at | 0.2285 | 0.6197 | |
| GSE20347 | FOXD2 | 2306 | 207653_at | 0.0430 | 0.4771 | |
| GSE23400 | FOXD2 | 2306 | 207653_at | 0.0520 | 0.0593 | |
| GSE26886 | FOXD2 | 2306 | 207653_at | 0.3131 | 0.0023 | |
| GSE29001 | FOXD2 | 2306 | 207653_at | -0.0084 | 0.9582 | |
| GSE38129 | FOXD2 | 2306 | 207653_at | -0.0031 | 0.9654 | |
| GSE45670 | FOXD2 | 2306 | 207653_at | 0.1486 | 0.0989 | |
| GSE53622 | FOXD2 | 2306 | 4853 | 2.1071 | 0.0000 | |
| GSE53624 | FOXD2 | 2306 | 4853 | 1.5593 | 0.0000 | |
| GSE63941 | FOXD2 | 2306 | 207653_at | 0.2675 | 0.2806 | |
| GSE77861 | FOXD2 | 2306 | 207653_at | 0.0006 | 0.9951 | |
| SRP133303 | FOXD2 | 2306 | RNAseq | 1.8779 | 0.0000 | |
| SRP219564 | FOXD2 | 2306 | RNAseq | 3.2037 | 0.0001 | |
| TCGA | FOXD2 | 2306 | RNAseq | 0.7460 | 0.0001 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by FOXD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FOXD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FOXD2 | 2306 | 4 | 3 | 23 | |
| GSE20123 | FOXD2 | 2306 | 4 | 2 | 24 | |
| GSE43470 | FOXD2 | 2306 | 5 | 1 | 37 | |
| GSE46452 | FOXD2 | 2306 | 2 | 1 | 56 | |
| GSE47630 | FOXD2 | 2306 | 8 | 4 | 28 | |
| GSE54993 | FOXD2 | 2306 | 0 | 1 | 69 | |
| GSE54994 | FOXD2 | 2306 | 11 | 2 | 40 | |
| GSE60625 | FOXD2 | 2306 | 0 | 0 | 11 | |
| GSE74703 | FOXD2 | 2306 | 4 | 1 | 31 | |
| GSE74704 | FOXD2 | 2306 | 2 | 0 | 18 | |
| TCGA | FOXD2 | 2306 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 32; Total Number of normals: 406.
Somatic mutations of FOXD2:
Generating mutation plots.
Highly correlated genes for FOXD2:
Showing top 20/618 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FOXD2 | CENPI | 0.78572 | 3 | 0 | 3 |
| FOXD2 | MMP11 | 0.78456 | 3 | 0 | 3 |
| FOXD2 | MMP1 | 0.777776 | 3 | 0 | 3 |
| FOXD2 | C1QTNF6 | 0.755881 | 3 | 0 | 3 |
| FOXD2 | BGN | 0.752772 | 3 | 0 | 3 |
| FOXD2 | LOXL2 | 0.752313 | 3 | 0 | 3 |
| FOXD2 | TGFBI | 0.751695 | 3 | 0 | 3 |
| FOXD2 | COL5A1 | 0.749162 | 3 | 0 | 3 |
| FOXD2 | COL5A2 | 0.747339 | 3 | 0 | 3 |
| FOXD2 | COL1A1 | 0.743537 | 4 | 0 | 4 |
| FOXD2 | CTHRC1 | 0.740932 | 3 | 0 | 3 |
| FOXD2 | XPO1 | 0.736569 | 3 | 0 | 3 |
| FOXD2 | ITGA6 | 0.732411 | 3 | 0 | 3 |
| FOXD2 | ACLY | 0.731359 | 3 | 0 | 3 |
| FOXD2 | CBX3 | 0.729116 | 3 | 0 | 3 |
| FOXD2 | LTB4R2 | 0.714704 | 3 | 0 | 3 |
| FOXD2 | ZFP64 | 0.713027 | 4 | 0 | 3 |
| FOXD2 | DNMT1 | 0.706238 | 4 | 0 | 4 |
| FOXD2 | ADAMTS2 | 0.705746 | 4 | 0 | 4 |
| FOXD2 | LPCAT1 | 0.705471 | 3 | 0 | 3 |
For details and further investigation, click here
