| Full name: solute carrier family 6 member 15 | Alias Symbol: hv7-3|NTT73|FLJ10316|V7-3|SBAT1 | ||
| Type: protein-coding gene | Cytoband: 12q21.31 | ||
| Entrez ID: 55117 | HGNC ID: HGNC:13621 | Ensembl Gene: ENSG00000072041 | OMIM ID: 607971 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC6A15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A15 | 55117 | 206376_at | 0.9048 | 0.5926 | |
| GSE20347 | SLC6A15 | 55117 | 206376_at | 0.8803 | 0.0198 | |
| GSE23400 | SLC6A15 | 55117 | 206376_at | 0.3186 | 0.0143 | |
| GSE26886 | SLC6A15 | 55117 | 206376_at | 0.3308 | 0.5434 | |
| GSE29001 | SLC6A15 | 55117 | 206376_at | 1.0787 | 0.1461 | |
| GSE38129 | SLC6A15 | 55117 | 206376_at | 0.7442 | 0.0135 | |
| GSE45670 | SLC6A15 | 55117 | 206376_at | -0.1356 | 0.8291 | |
| GSE53622 | SLC6A15 | 55117 | 48190 | 0.2382 | 0.5108 | |
| GSE53624 | SLC6A15 | 55117 | 48190 | -0.0168 | 0.9570 | |
| GSE63941 | SLC6A15 | 55117 | 232263_at | 0.3296 | 0.8625 | |
| GSE77861 | SLC6A15 | 55117 | 206376_at | 0.3013 | 0.5129 | |
| GSE97050 | SLC6A15 | 55117 | A_33_P3392320 | 0.7711 | 0.1242 | |
| SRP007169 | SLC6A15 | 55117 | RNAseq | 0.9576 | 0.1310 | |
| SRP008496 | SLC6A15 | 55117 | RNAseq | 1.5928 | 0.0781 | |
| SRP064894 | SLC6A15 | 55117 | RNAseq | 1.4038 | 0.0057 | |
| SRP133303 | SLC6A15 | 55117 | RNAseq | 1.4895 | 0.0000 | |
| SRP159526 | SLC6A15 | 55117 | RNAseq | 1.2213 | 0.2011 | |
| TCGA | SLC6A15 | 55117 | RNAseq | 1.1994 | 0.0010 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SLC6A15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A15 | 55117 | 3 | 3 | 24 | |
| GSE20123 | SLC6A15 | 55117 | 3 | 3 | 24 | |
| GSE43470 | SLC6A15 | 55117 | 3 | 1 | 39 | |
| GSE46452 | SLC6A15 | 55117 | 9 | 1 | 49 | |
| GSE47630 | SLC6A15 | 55117 | 10 | 1 | 29 | |
| GSE54993 | SLC6A15 | 55117 | 0 | 5 | 65 | |
| GSE54994 | SLC6A15 | 55117 | 7 | 1 | 45 | |
| GSE60625 | SLC6A15 | 55117 | 0 | 0 | 11 | |
| GSE74703 | SLC6A15 | 55117 | 3 | 1 | 32 | |
| GSE74704 | SLC6A15 | 55117 | 1 | 3 | 16 | |
| TCGA | SLC6A15 | 55117 | 18 | 10 | 68 |
Total number of gains: 57; Total number of losses: 29; Total Number of normals: 402.
Somatic mutations of SLC6A15:
Generating mutation plots.
Highly correlated genes for SLC6A15:
Showing top 20/348 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A15 | CXCL3 | 0.754333 | 4 | 0 | 4 |
| SLC6A15 | G0S2 | 0.739715 | 3 | 0 | 3 |
| SLC6A15 | FKBP11 | 0.739677 | 3 | 0 | 3 |
| SLC6A15 | SLC15A4 | 0.738054 | 4 | 0 | 4 |
| SLC6A15 | ARL5B | 0.735919 | 3 | 0 | 3 |
| SLC6A15 | CYP27C1 | 0.730621 | 3 | 0 | 3 |
| SLC6A15 | USP45 | 0.727995 | 3 | 0 | 3 |
| SLC6A15 | IL1B | 0.721658 | 3 | 0 | 3 |
| SLC6A15 | GINS4 | 0.714366 | 4 | 0 | 4 |
| SLC6A15 | PDE7A | 0.71315 | 3 | 0 | 3 |
| SLC6A15 | PCSK1 | 0.701689 | 3 | 0 | 3 |
| SLC6A15 | MBTPS2 | 0.697213 | 3 | 0 | 3 |
| SLC6A15 | MTRR | 0.696966 | 3 | 0 | 3 |
| SLC6A15 | ANGPT2 | 0.694078 | 3 | 0 | 3 |
| SLC6A15 | FCGR2A | 0.693283 | 4 | 0 | 4 |
| SLC6A15 | GPR158 | 0.692416 | 4 | 0 | 3 |
| SLC6A15 | CHMP7 | 0.688955 | 3 | 0 | 3 |
| SLC6A15 | HAS2 | 0.687116 | 4 | 0 | 3 |
| SLC6A15 | NPFFR2 | 0.683674 | 3 | 0 | 3 |
| SLC6A15 | MRPS5 | 0.681327 | 3 | 0 | 3 |
For details and further investigation, click here
