| Full name: raftlin family member 2 | Alias Symbol: FLJ30574|Raftlin-2 | ||
| Type: protein-coding gene | Cytoband: 2q33.1 | ||
| Entrez ID: 130132 | HGNC ID: HGNC:26402 | Ensembl Gene: ENSG00000162944 | OMIM ID: 618215 |
| Drug and gene relationship at DGIdb | |||
Expression of RFTN2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFTN2 | 130132 | 238955_at | 0.1868 | 0.5327 | |
| GSE26886 | RFTN2 | 130132 | 238955_at | -0.2545 | 0.0920 | |
| GSE45670 | RFTN2 | 130132 | 238955_at | 0.0949 | 0.4004 | |
| GSE63941 | RFTN2 | 130132 | 238955_at | -0.1097 | 0.8497 | |
| GSE77861 | RFTN2 | 130132 | 238955_at | 0.1385 | 0.1499 | |
| GSE97050 | RFTN2 | 130132 | A_23_P363878 | 0.0253 | 0.9566 | |
| SRP007169 | RFTN2 | 130132 | RNAseq | 0.9587 | 0.0981 | |
| SRP064894 | RFTN2 | 130132 | RNAseq | 0.5309 | 0.1066 | |
| SRP133303 | RFTN2 | 130132 | RNAseq | -0.0306 | 0.8251 | |
| SRP159526 | RFTN2 | 130132 | RNAseq | 0.6575 | 0.1520 | |
| SRP193095 | RFTN2 | 130132 | RNAseq | 0.4026 | 0.0004 | |
| SRP219564 | RFTN2 | 130132 | RNAseq | 0.2254 | 0.6129 | |
| TCGA | RFTN2 | 130132 | RNAseq | -0.1776 | 0.2244 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RFTN2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of RFTN2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFTN2 | 130132 | 10 | 2 | 18 | |
| GSE20123 | RFTN2 | 130132 | 10 | 2 | 18 | |
| GSE43470 | RFTN2 | 130132 | 3 | 1 | 39 | |
| GSE46452 | RFTN2 | 130132 | 1 | 4 | 54 | |
| GSE47630 | RFTN2 | 130132 | 4 | 5 | 31 | |
| GSE54993 | RFTN2 | 130132 | 0 | 3 | 67 | |
| GSE54994 | RFTN2 | 130132 | 10 | 9 | 34 | |
| GSE60625 | RFTN2 | 130132 | 0 | 3 | 8 | |
| GSE74703 | RFTN2 | 130132 | 2 | 1 | 33 | |
| GSE74704 | RFTN2 | 130132 | 5 | 2 | 13 | |
| TCGA | RFTN2 | 130132 | 22 | 9 | 65 |
Total number of gains: 67; Total number of losses: 41; Total Number of normals: 380.
Somatic mutations of RFTN2:
Generating mutation plots.
Highly correlated genes for RFTN2:
Showing top 20/124 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFTN2 | SIVA1 | 0.830451 | 3 | 0 | 3 |
| RFTN2 | ITM2C | 0.820162 | 3 | 0 | 3 |
| RFTN2 | CHN1 | 0.812964 | 3 | 0 | 3 |
| RFTN2 | PRSS36 | 0.809935 | 3 | 0 | 3 |
| RFTN2 | PARVB | 0.794405 | 3 | 0 | 3 |
| RFTN2 | PKN1 | 0.791248 | 3 | 0 | 3 |
| RFTN2 | PDGFRB | 0.788442 | 3 | 0 | 3 |
| RFTN2 | RHOBTB2 | 0.78108 | 3 | 0 | 3 |
| RFTN2 | G0S2 | 0.769201 | 3 | 0 | 3 |
| RFTN2 | ENG | 0.763689 | 3 | 0 | 3 |
| RFTN2 | COL6A2 | 0.756863 | 3 | 0 | 3 |
| RFTN2 | MGAT5 | 0.756552 | 3 | 0 | 3 |
| RFTN2 | EMP3 | 0.74979 | 3 | 0 | 3 |
| RFTN2 | TNFAIP6 | 0.746375 | 3 | 0 | 3 |
| RFTN2 | RAB12 | 0.738401 | 3 | 0 | 3 |
| RFTN2 | GCLC | 0.73432 | 4 | 0 | 4 |
| RFTN2 | MRM1 | 0.730994 | 3 | 0 | 3 |
| RFTN2 | ADAM19 | 0.725408 | 3 | 0 | 3 |
| RFTN2 | CDC14A | 0.723613 | 3 | 0 | 3 |
| RFTN2 | CD99L2 | 0.723505 | 3 | 0 | 3 |
For details and further investigation, click here
