| Full name: proteasome subunit beta 5 | Alias Symbol: MB1 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 5693 | HGNC ID: HGNC:9542 | Ensembl Gene: ENSG00000100804 | OMIM ID: 600306 |
| Drug and gene relationship at DGIdb | |||
Expression of PSMB5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMB5 | 5693 | 208799_at | 0.5886 | 0.4256 | |
| GSE20347 | PSMB5 | 5693 | 208799_at | 0.6255 | 0.0043 | |
| GSE23400 | PSMB5 | 5693 | 208799_at | 0.6807 | 0.0000 | |
| GSE26886 | PSMB5 | 5693 | 208799_at | -0.3213 | 0.2331 | |
| GSE29001 | PSMB5 | 5693 | 208799_at | 0.5720 | 0.1836 | |
| GSE38129 | PSMB5 | 5693 | 208799_at | 0.7013 | 0.0000 | |
| GSE45670 | PSMB5 | 5693 | 208799_at | 0.6823 | 0.0003 | |
| GSE53622 | PSMB5 | 5693 | 3448 | 0.4740 | 0.0000 | |
| GSE53624 | PSMB5 | 5693 | 3448 | 0.5243 | 0.0000 | |
| GSE63941 | PSMB5 | 5693 | 208799_at | -0.2979 | 0.5893 | |
| GSE77861 | PSMB5 | 5693 | 208799_at | 0.7824 | 0.0464 | |
| GSE97050 | PSMB5 | 5693 | A_23_P37191 | 0.1161 | 0.6806 | |
| SRP007169 | PSMB5 | 5693 | RNAseq | 0.2039 | 0.5511 | |
| SRP008496 | PSMB5 | 5693 | RNAseq | 0.1278 | 0.4864 | |
| SRP064894 | PSMB5 | 5693 | RNAseq | 0.6314 | 0.0042 | |
| SRP133303 | PSMB5 | 5693 | RNAseq | 0.8495 | 0.0007 | |
| SRP159526 | PSMB5 | 5693 | RNAseq | 0.6189 | 0.0086 | |
| SRP193095 | PSMB5 | 5693 | RNAseq | 0.3450 | 0.0588 | |
| SRP219564 | PSMB5 | 5693 | RNAseq | 0.4287 | 0.1796 | |
| TCGA | PSMB5 | 5693 | RNAseq | 0.2093 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMB5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMB5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMB5 | 5693 | 9 | 2 | 19 | |
| GSE20123 | PSMB5 | 5693 | 9 | 2 | 19 | |
| GSE43470 | PSMB5 | 5693 | 7 | 2 | 34 | |
| GSE46452 | PSMB5 | 5693 | 17 | 2 | 40 | |
| GSE47630 | PSMB5 | 5693 | 11 | 10 | 19 | |
| GSE54993 | PSMB5 | 5693 | 3 | 11 | 56 | |
| GSE54994 | PSMB5 | 5693 | 18 | 5 | 30 | |
| GSE60625 | PSMB5 | 5693 | 0 | 2 | 9 | |
| GSE74703 | PSMB5 | 5693 | 6 | 2 | 28 | |
| GSE74704 | PSMB5 | 5693 | 4 | 1 | 15 | |
| TCGA | PSMB5 | 5693 | 27 | 15 | 54 |
Total number of gains: 111; Total number of losses: 54; Total Number of normals: 323.
Somatic mutations of PSMB5:
Generating mutation plots.
Highly correlated genes for PSMB5:
Showing top 20/338 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMB5 | C14orf119 | 0.767528 | 5 | 0 | 4 |
| PSMB5 | POC1A | 0.724221 | 4 | 0 | 4 |
| PSMB5 | SFT2D1 | 0.709419 | 5 | 0 | 5 |
| PSMB5 | MRPS2 | 0.697869 | 9 | 0 | 9 |
| PSMB5 | LTB4R | 0.696059 | 4 | 0 | 3 |
| PSMB5 | GPRIN1 | 0.691396 | 4 | 0 | 4 |
| PSMB5 | LRR1 | 0.690394 | 6 | 0 | 6 |
| PSMB5 | PRMT5 | 0.681035 | 12 | 0 | 10 |
| PSMB5 | PLEKHG4 | 0.675916 | 3 | 0 | 3 |
| PSMB5 | RANBP1 | 0.674531 | 9 | 0 | 8 |
| PSMB5 | NPW | 0.673343 | 4 | 0 | 4 |
| PSMB5 | ZNF114 | 0.670595 | 3 | 0 | 3 |
| PSMB5 | BMS1 | 0.669739 | 5 | 0 | 4 |
| PSMB5 | PSMD11 | 0.668661 | 11 | 0 | 11 |
| PSMB5 | RUVBL1 | 0.668655 | 9 | 0 | 7 |
| PSMB5 | POU6F2-AS2 | 0.668325 | 3 | 0 | 3 |
| PSMB5 | AHSA1 | 0.668198 | 10 | 0 | 9 |
| PSMB5 | UBE2S | 0.668172 | 8 | 0 | 7 |
| PSMB5 | TMEM251 | 0.66481 | 8 | 0 | 7 |
| PSMB5 | SH2D5 | 0.664346 | 4 | 0 | 4 |
For details and further investigation, click here
